Overexpression of the V3 variant of versican alters arterial smooth muscle cell adhesion, migration, and proliferation in vitro.
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Versican degradation and vascular diseaseRhoGDI2 suppresses lung metastasis in mice by reducing tumor versican expression and macrophage infiltration.CCN5 is a growth arrest-specific gene that regulates smooth muscle cell proliferation and motilityCCN5 modulates the antiproliferative effect of heparin and regulates cell motility in vascular smooth muscle cellsVersican and the regulation of cell phenotype in diseaseExpression of versican isoform V3 in the absence of ascorbate improves elastogenesis in engineered vascular constructs.Versican and the control of inflammation.Transforming growth factor beta3 regulates the versican variants in the extracellular matrix-rich uterine leiomyomas.Versican regulates metastasis of epithelial ovarian carcinoma cells and spheroids.Expression of versican V3 by arterial smooth muscle cells alters tumor growth factor β (TGFβ)-, epidermal growth factor (EGF)-, and nuclear factor κB (NFκB)-dependent signaling pathways, creating a microenvironment that resists monocyte adhesion.Retrovirally mediated overexpression of versican v3 reverses impaired elastogenesis and heightened proliferation exhibited by fibroblasts from Costello syndrome and Hurler disease patients.Versican isoforms modulate expression and function of nicotinic acetylcholine receptorsNeointima formed by arterial smooth muscle cells expressing versican variant V3 is resistant to lipid and macrophage accumulationInterleukin-11 promotes the progress of gastric carcinoma via abnormally expressed versican.Expression of V3 Versican by Rat Arterial Smooth Muscle Cells Promotes Differentiated and Anti-inflammatory PhenotypesMitral valvular interstitial cells demonstrate regional, adhesional, and synthetic heterogeneity.Novel VCAN mutations and evidence for unbalanced alternative splicing in the pathogenesis of Wagner syndrome.ADAMTS-1 and ADAMTS-4 levels are elevated in thoracic aortic aneurysms and dissections.Retrovirally mediated overexpression of glycosaminoglycan-deficient biglycan in arterial smooth muscle cells induces tropoelastin synthesis and elastic fiber formation in vitro and in neointimae after vascular injuryVersican accumulates in vascular lesions in pulmonary arterial hypertension.Pro-inflammatory phenotype of COPD fibroblasts not compatible with repair in COPD lung.Versican V2 isoform enhances angiogenesis by regulating endothelial cell activities and fibronectin expression.Versican V1 isoform regulates cell-associated matrix formation and cell behavior differentially from aggrecan in Swarm rat chondrosarcoma cells.V3 versican isoform alters the behavior of human melanoma cells by interfering with CD44/ErbB-dependent signaling.Structure and regulation of the versican promoter: the versican promoter is regulated by AP-1 and TCF transcription factors in invasive human melanoma cells.V3 versican isoform expression has a dual role in human melanoma tumor growth and metastasis.Versican G3 domain promotes blood coagulation through suppressing the activity of tissue factor pathway inhibitor-1.Versican/PG-M regulates chondrogenesis as an extracellular matrix molecule crucial for mesenchymal condensation.Versican G1 domain and V3 isoform overexpression results in increased chondrogenesis in the developing chick limb in ovo.Critical Role of ADAMTS-4 in the Development of Sporadic Aortic Aneurysm and Dissection in Mice.Differentiation of cardiomyocytes from human embryonic stem cells is accompanied by changes in the extracellular matrix production of versican and hyaluronan.Mechanical properties and compositions of tissue engineered and native arteries.Distribution of PG-M/versican variants in human tissues and de novo expression of isoform V3 upon endothelial cell activation, migration, and neoangiogenesis in vitro.Versican in epithelial ovarian cancer: relation to hyaluronan, clinicopathologic factors and prognosis.Stromal Versican Regulates Tumor Growth by Promoting Angiogenesis.Analogous effects of recombinant human full-length amelogenin expressed by Pichia pastoris yeast and enamel matrix derivative in vitro.Massive aggrecan and versican accumulation in thoracic aortic aneurysm and dissection.ADAMTS9-Regulated Pericellular Matrix Dynamics Governs Focal Adhesion-Dependent Smooth Muscle Differentiation.Use of versican variant V3 and versican antisense expression to engineer cultured human skin containing increased content of insoluble elastin.Versican upregulation in Sézary cells alters growth, motility and resistance to chemotherapy.
P2860
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P2860
Overexpression of the V3 variant of versican alters arterial smooth muscle cell adhesion, migration, and proliferation in vitro.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh-hant
name
Overexpression of the V3 varia ...... n, and proliferation in vitro.
@en
Overexpression of the V3 varia ...... n, and proliferation in vitro.
@nl
type
label
Overexpression of the V3 varia ...... n, and proliferation in vitro.
@en
Overexpression of the V3 varia ...... n, and proliferation in vitro.
@nl
prefLabel
Overexpression of the V3 varia ...... n, and proliferation in vitro.
@en
Overexpression of the V3 varia ...... n, and proliferation in vitro.
@nl
P2093
P2860
P356
P1476
Overexpression of the V3 varia ...... on, and proliferation in vitro
@en
P2093
Kathleen R Braun
Mervyn J Merrilees
Thomas N Wight
P2860
P356
10.1002/JCP.10043
P577
2002-01-01T00:00:00Z