Heterogeneous expression of Ca(2+) handling proteins in rabbit sinoatrial node.
about
Dysfunction in ankyrin-B-dependent ion channel and transporter targeting causes human sinus node diseaseSinus node dysfunction following targeted disruption of the murine cardiac sodium channel gene Scn5aHierarchical clustering of ryanodine receptors enables emergence of a calcium clock in sinoatrial node cells.A coupled SYSTEM of intracellular Ca2+ clocks and surface membrane voltage clocks controls the timekeeping mechanism of the heart's pacemaker.Self-beating atypically shaped cardiomyocytes survive a long-term postnatal development while preserving the expression of fetal cardiac genes in mice.The mouse sino-atrial node expresses both the type 2 and type 3 Ca(2+) release channels/ryanodine receptors.Synchronization of stochastic Ca²(+) release units creates a rhythmic Ca²(+) clock in cardiac pacemaker cellsModern perspectives on numerical modeling of cardiac pacemaker cellNumerical models based on a minimal set of sarcolemmal electrogenic proteins and an intracellular Ca(2+) clock generate robust, flexible, and energy-efficient cardiac pacemaking.What keeps us ticking: a funny current, a calcium clock, or both?Resurgence of cardiac t-tubule research.Ca(2+)-Clock-Dependent Pacemaking in the Sinus Node Is Impaired in Mice with a Cardiac Specific Reduction in SERCA2 AbundanceThe missing link in the mystery of normal automaticity of cardiac pacemaker cells.Genesis and regulation of the heart automaticity.Regulation of basal and reserve cardiac pacemaker function by interactions of cAMP-mediated PKA-dependent Ca2+ cycling with surface membrane channels.Expression of connexin 43, ion channels and Ca2+-handling proteins in rat pulmonary vein cardiomyocytes.Regulation of calcium clock-mediated pacemaking by inositol-1,4,5-trisphosphate receptors in mouse sinoatrial nodal cells.Altered Na/Ca exchange distribution in ventricular myocytes from failing hearts.Regional difference in dynamical property of sinoatrial node pacemaking: role of na+ channel current.Stabilization of diastolic calcium signal via calcium pump regulation of complex local calcium releases and transient decay in a computational model of cardiac pacemaker cell with individual release channels.Ca(2+) cycling properties are conserved despite bradycardic effects of heart failure in sinoatrial node cells.Electrophysiological heterogeneity of pacemaker cells in rabbit intercaval region, including SA node: insights from recording multiple ion currents in each cell.Local control of Ca2+-induced Ca2+ release in mouse sinoatrial node cells.Effect of hyperpolarization-activated current I(f) on robustness of sinoatrial node pacemaking: theoretical study on influence of intracellular Na(+) concentration.Effects of ACh and adenosine mediated by Kir3.1 and Kir3.4 on ferret ventricular cells.Intracellular Ca2+ and pacemaking within the rabbit sinoatrial node: heterogeneity of role and control.P2 purinergic receptor mRNA in rat and human sinoatrial node and other heart regions.Effects of streptozotocin-induced diabetes on connexin43 mRNA and protein expression in ventricular muscle.Heterogeneous functional expression of the sustained inward Na+ current in guinea pig sinoatrial node cells.Roles of sarcoplasmic reticulum Ca2+ cycling and Na+/Ca2+ exchanger in sinoatrial node pacemaking: insights from bifurcation analysis of mathematical models.Minor contribution of cytosolic Ca2+ transients to the pacemaker rhythm in guinea pig sinoatrial node cells.The Subcellular Distribution of Ryanodine Receptors and L-Type Ca Channels Modulates Ca-Transient Properties and Spontaneous Ca-Release Events in Atrial Cardiomyocytes
P2860
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P2860
Heterogeneous expression of Ca(2+) handling proteins in rabbit sinoatrial node.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh-hant
name
Heterogeneous expression of Ca
@nl
Heterogeneous expression of Ca(2+) handling proteins in rabbit sinoatrial node.
@en
type
label
Heterogeneous expression of Ca
@nl
Heterogeneous expression of Ca(2+) handling proteins in rabbit sinoatrial node.
@en
prefLabel
Heterogeneous expression of Ca
@nl
Heterogeneous expression of Ca(2+) handling proteins in rabbit sinoatrial node.
@en
P2093
P2860
P1476
Heterogeneous expression of Ca(2+) handling proteins in rabbit sinoatrial node.
@en
P2093
Halina Dobrzynski
Hanny Musa
Hauro Honjo
Itsuo Kodama
Mark R Boyett
Mathew K Lancaster
Sandra A Jones
Yoshiko Takagishi
Zaineb Henderson
P2860
P304
P356
10.1177/002215540205000303
P50
P577
2002-03-01T00:00:00Z