Telomerase overexpression in K562 leukemia cells protects against apoptosis by serum deprivation and double-stranded DNA break inducing agents, but not against DNA synthesis inhibitors.
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The role of the JAK-STAT pathway and related signal cascades in telomerase activation during the development of hematologic malignanciesThe MAPK pathway signals telomerase modulation in response to isothiocyanate-induced DNA damage of human liver cancer cellsEpidermal growth factor induction of phenotype-dependent cell cycle arrest in vascular smooth muscle cells is through the mitogen-activated protein kinase pathwayTelomerase contributes to fludarabine resistance in primary human leukemic lymphocytes.Expression of (NES-)hTERT in cancer cells delays cell cycle progression and increases sensitivity to genotoxic stressTelomere DNA deficiency is associated with development of human embryonic aneuploidyMechanism of telomerase activation by v-Rel and its contribution to transformation.Telomere profiling: toward glioblastoma personalized medicine.Telomere shortening unrelated to smoking, body weight, physical activity, and alcohol intake: 4,576 general population individuals with repeat measurements 10 years apart.A chemical enucleation method for the transfer of mitochondrial DNA to rho(o) cells.Telomeres, telomerase, and apoptosis.Enhanced inhibition of clonogenic survival of human medulloblastoma cells by multimodal treatment with ionizing irradiation, epigenetic modifiers, and differentiation-inducing drugsTea polyphenols, their biological effects and potential molecular targets.Cellular players in the herpes simplex virus dependent apoptosis balancing act.Resistance to the short term antiproliferative activity of the G-quadruplex ligand 12459 is associated with telomerase overexpression and telomere capping alteration.Targeting telomerase with radiolabeled inhibitors.Omacetaxine mepesuccinate induces apoptosis and cell cycle arrest, promotes cell differentiation, and reduces telomerase activity in diffuse large B‑cell lymphoma cells.The isothiocyanate erucin abrogates telomerase in hepatocellular carcinoma cells in vitro and in an orthotopic xenograft tumour model of HCC.Radiation-induced upregulation of telomerase activity escapes PI3-kinase inhibition in two malignant glioma cell lines.Knockdown of hTERT alters biophysical properties of K562 cells resulting in decreased migration rate in vitro.Synergistic/additive interaction of valproic acid with bortezomib on proliferation and apoptosis of acute myeloid leukemia cells.Telomerase inhibition improves tumor response to radiotherapy in a murine orthotopic model of human glioblastoma.Single cell measurement of telomerase expression and splicing using microfluidic emulsion culturesLeukemic cells with increased telomerase activity exhibit resistance to imatinib.
P2860
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P2860
Telomerase overexpression in K562 leukemia cells protects against apoptosis by serum deprivation and double-stranded DNA break inducing agents, but not against DNA synthesis inhibitors.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
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2002年學術文章
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2002年學術文章
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name
Telomerase overexpression in K ...... inst DNA synthesis inhibitors.
@en
Telomerase overexpression in K ...... inst DNA synthesis inhibitors.
@nl
type
label
Telomerase overexpression in K ...... inst DNA synthesis inhibitors.
@en
Telomerase overexpression in K ...... inst DNA synthesis inhibitors.
@nl
prefLabel
Telomerase overexpression in K ...... inst DNA synthesis inhibitors.
@en
Telomerase overexpression in K ...... inst DNA synthesis inhibitors.
@nl
P2093
P1433
P1476
Telomerase overexpression in K ...... inst DNA synthesis inhibitors.
@en
P2093
Hideaki Mizoguchi
Hisashi Yamada
Masaharu Akiyama
Naotoshi Kanda
Osamu Yamada
Shinobu Akita
Takeshi Kawano
Tsuneya Ohno
Yoshikatsu Eto
P304
P356
10.1016/S0304-3835(01)00838-2
P407
P577
2002-04-01T00:00:00Z