Protection against acute lung injury by intravenous or intratracheal pretreatment with EPI-HNE-4, a new potent neutrophil elastase inhibitor.
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The Role of Serine Proteases and Antiproteases in the Cystic Fibrosis LungInterleukin-6 via sputum induction as biomarker of inflammation for indoor particulate matter among primary school children in Klang Valley, Malaysia.The small GTPase Rap1b negatively regulates neutrophil chemotaxis and transcellular diapedesis by inhibiting Akt activation.Neutrophil elastase cleaves epithelial cadherin in acutely injured lung epitheliumStructural characterization of mouse neutrophil serine proteases and identification of their substrate specificities: relevance to mouse models of human inflammatory diseasesNeutrophil elastase inhibitors as treatment for COPD.Cloning and Characterization of Two Potent Kunitz Type Protease Inhibitors from Echinococcus granulosusRole of neutrophil elastase in LTB4-induced neutrophil transmigration in vivo assessed with a specific inhibitor and neutrophil elastase deficient miceVenular basement membranes contain specific matrix protein low expression regions that act as exit points for emigrating neutrophilsTransepithelial migration of neutrophils: mechanisms and implications for acute lung injuryAnti-inflammatory therapies for cystic fibrosis-related lung disease.Proteases and antiproteases in chronic neutrophilic lung disease - relevance to drug discovery.Regulation of the epithelial Na+ channel and airway surface liquid volume by serine proteases.Contribution of neutrophils to acute lung injuryInhibitors of cathepsin G: a patent review (2005 to present).Mammalian short palate lung and nasal epithelial clone 1 (SPLUNC1) in pH-dependent airway hydrationShark variable new antigen receptor biologics - a novel technology platform for therapeutic drug development.Neutrophil elastase is needed for neutrophil emigration into lungs in ventilator-induced lung injuryNeutrophil elastase activates near-silent epithelial Na+ channels and increases airway epithelial Na+ transport.Determinants of culture success in an airway epithelium sampling program of young children with cystic fibrosis.Neutrophil elastase modulates cytokine expression: contribution to host defense against Pseudomonas aeruginosa-induced pneumonia.Kinetics of the inhibition of neutrophil proteinases by recombinant elafin and pre-elafin (trappin-2) expressed in Pichia pastoris.Neutrophil elastase activity compensates for a genetic lack of matrix metalloproteinase-9 (MMP-9) in leukocyte infiltration in a model of experimental peritonitis.The involvement of nitric oxide, nitric oxide synthase, neutrophil elastase, myeloperoxidase and proinflammatory cytokines in the acute lung injury caused by phorbol myristate acetate.Nocturnal hypoxic stress activates invasive ability of monocytes in patients with obstructive sleep apnoea syndrome.A novel neutrophil elastase inhibitor prevents elastase activation and surface cleavage of the epithelial sodium channel expressed in Xenopus laevis oocytes.Deficiency in neutrophil elastase does not impair neutrophil recruitment to inflamed sites.
P2860
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P2860
Protection against acute lung injury by intravenous or intratracheal pretreatment with EPI-HNE-4, a new potent neutrophil elastase inhibitor.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh-hant
name
Protection against acute lung ...... neutrophil elastase inhibitor.
@en
Protection against acute lung ...... neutrophil elastase inhibitor.
@nl
type
label
Protection against acute lung ...... neutrophil elastase inhibitor.
@en
Protection against acute lung ...... neutrophil elastase inhibitor.
@nl
prefLabel
Protection against acute lung ...... neutrophil elastase inhibitor.
@en
Protection against acute lung ...... neutrophil elastase inhibitor.
@nl
P2093
P2860
P356
P1476
Protection against acute lung ...... neutrophil elastase inhibitor.
@en
P2093
Alain Harf
Alain Poncin
Chantal Lafuma
Christophe Delacourt
Christophe Delclaux
François Saudubray
Micheline Levame
Sabine Hérigault
P2860
P304
P356
10.1165/AJRCMB.26.3.4611
P577
2002-03-01T00:00:00Z