Computer modeling of three-dimensional structure of DNA-packaging RNA (pRNA) monomer, dimer, and hexamer of Phi29 DNA packaging motor.
about
The emerging field of RNA nanotechnologyBinding of pRNA to the N-terminal 14 amino acids of connector protein of bacteriophage phi29Structure and assembly of the essential RNA ring component of a viral DNA packaging motorCrystal structure of 3WJ core revealing divalent ion-promoted thermostability and assembly of the Phi29 hexameric motor pRNADiscovery of a new motion mechanism of biomotors similar to the earth revolving around the sun without rotation.Controllable self-assembly of nanoparticles for specific delivery of multiple therapeutic molecules to cancer cells using RNA nanotechnologyNovel mechanism of hexamer ring assembly in protein/RNA interactions revealed by single molecule imaging.Construction of bacteriophage phi29 DNA packaging motor and its applications in nanotechnology and therapyGlobal structure of a three-way junction in a phi29 packaging RNA dimer determined using site-directed spin labeling.RNA nanotechnology: engineering, assembly and applications in detection, gene delivery and therapyAptamer-targeted cell-specific RNA interferenceDual-channel single-molecule fluorescence resonance energy transfer to establish distance parameters for RNA nanoparticles.Fabrication of stable and RNase-resistant RNA nanoparticles active in gearing the nanomotors for viral DNA packaging.Dual functional RNA nanoparticles containing phi29 motor pRNA and anti-gp120 aptamer for cell-type specific delivery and HIV-1 inhibitionPharmacological characterization of chemically synthesized monomeric phi29 pRNA nanoparticles for systemic delivery.Evaluation of end-capped DNA modules for pRNA capture and functionalization.Instrumentation and metrology for single RNA counting in biological complexes or nanoparticles by a single-molecule dual-view system.Progress on RNAi-based molecular medicines.Analysis of intermolecular base pair formation of prohead RNA of the phage phi29 DNA packaging motor using NMR spectroscopyViral nanomotors for packaging of dsDNA and dsRNAThree-way junction conformation dictates self-association of phage packaging RNAsRNA nanotechnology for computer design and in vivo computation.Stable RNA nanoparticles as potential new generation drugs for cancer therapy.Nanobiosystems.Thermodynamic stabilities of three-way junction nanomotifs in prohead RNA.Insights into the structure and assembly of the bacteriophage 29 double-stranded DNA packaging motorAssembly of multifunctional phi29 pRNA nanoparticles for specific delivery of siRNA and other therapeutics to targeted cellsAssembly mechanism of the sixty-subunit nanoparticles via interaction of RNA with the reengineered protein connector of phi29 DNA-packaging motor.Specific delivery of therapeutic RNAs to cancer cells via the dimerization mechanism of phi29 motor pRNA.Construction of folate-conjugated pRNA of bacteriophage phi29 DNA packaging motor for delivery of chimeric siRNA to nasopharyngeal carcinoma cells.Structural characterization of an intermolecular RNA-RNA interaction involved in the transcription regulation element of a bipartite plant virus.Bottom-up Assembly of RNA Arrays and Superstructures as Potential Parts in Nanotechnology.Defining molecular and domain boundaries in the bacteriophage phi29 DNA packaging motor.Diverse self-association properties within a family of phage packaging RNAs.Alanine scanning and Fe-BABE probing of the bacteriophage ø29 prohead RNA-connector interaction.A boost for the emerging field of RNA nanotechnologyA viral RNA that binds ATP and contains a motif similar to an ATP-binding aptamer from SELEX.Bacterial virus phi29 pRNA as a hammerhead ribozyme escort to destroy hepatitis B virus.
P2860
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P2860
Computer modeling of three-dimensional structure of DNA-packaging RNA (pRNA) monomer, dimer, and hexamer of Phi29 DNA packaging motor.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh-hant
name
Computer modeling of three-dim ...... of Phi29 DNA packaging motor.
@en
Computer modeling of three-dim ...... of Phi29 DNA packaging motor.
@nl
type
label
Computer modeling of three-dim ...... of Phi29 DNA packaging motor.
@en
Computer modeling of three-dim ...... of Phi29 DNA packaging motor.
@nl
prefLabel
Computer modeling of three-dim ...... of Phi29 DNA packaging motor.
@en
Computer modeling of three-dim ...... of Phi29 DNA packaging motor.
@nl
P2860
P356
P1476
Computer modeling of three-dim ...... of Phi29 DNA packaging motor.
@en
P2093
Peixuan Guo
Stephen Hoeprich
P2860
P304
20794-20803
P356
10.1074/JBC.M112061200
P407
P577
2002-03-08T00:00:00Z