Hepatic covalent adduct formation with zomepirac in the CD26-deficient mouse.

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Drug bioactivation, covalent binding to target proteins and toxicity relevance.The in vivo expression of dipeptidyl peptidases 8 and 9.

P2860

Q36061821-D301D1CE-6677-469D-9CB4-D05F39FE6531 Q37389403-C78C4BBF-52D5-45AB-8C32-D70F9C84DC47

P2860

Hepatic covalent adduct formation with zomepirac in the CD26-deficient mouse.

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http://www.wikidata.org/entity/Q43918476

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2002 nî lūn-bûn

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2002年の論文

@ja

2002年学术文章

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2002年学术文章

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2002年学术文章

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@zh-hans

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@zh-my

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@zh-sg

2002年學術文章

@yue

2002年學術文章

@zh-hant

name

Hepatic covalent adduct formation with zomepirac in the CD26-deficient mouse.

@en

Hepatic covalent adduct formation with zomepirac in the CD26-deficient mouse.

@nl

type

Item

label

Hepatic covalent adduct formation with zomepirac in the CD26-deficient mouse.

@en

Hepatic covalent adduct formation with zomepirac in the CD26-deficient mouse.

@nl

prefLabel

Hepatic covalent adduct formation with zomepirac in the CD26-deficient mouse.

@en

Hepatic covalent adduct formation with zomepirac in the CD26-deficient mouse.

@nl

P1476

Hepatic covalent adduct formation with zomepirac in the CD26-deficient mouse.

@en

P2093

Didier Marguet

http://www.w3.org/2001/XMLSchema#string

Min Wang

http://www.w3.org/2001/XMLSchema#string

Rene Jaggi

http://www.w3.org/2001/XMLSchema#string

Ronald G Dickinson

http://www.w3.org/2001/XMLSchema#string

P2860

Cloning, expression and chromosomal localization of a novel human dipeptidyl peptidase (DPP) IV homolog, DPP8

Irreversible binding of zomepirac to plasma protein in vitro and in vivo

Dipeptidyl peptidase IV is a target for covalent adduct formation with the acyl glucuronide metabolite of the anti-inflammatory drug zomepirac.

CD26, let it cut or cut it down.

Dipeptidyl-peptidase IV (CD26)--role in the inactivation of regulatory peptides.

Molecular pathogenesis of liver disease: an approach to hepatic inflammation, cirrhosis and liver transplant tolerance.

Post-proline-cleaving peptidases having DP IV like enzyme activity. Post-proline peptidases.

CD26: a multifunctional integral membrane and secreted protein of activated lymphocytes.

Enhanced insulin secretion and improved glucose tolerance in mice lacking CD26.

Acyl glucuronides revisited: is the glucuronidation process a toxification as well as a detoxification mechanism?

P304

66-71

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P31

scholarly article

P356

10.1046/J.1440-1746.2002.02662.X

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P433

http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

P50

Mark D. Gorrell

Catherine A. Abbott

P577

2002-01-01T00:00:00Z

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P5875

11467277

http://www.w3.org/2001/XMLSchema#string

P698

11895555

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Hepatic covalent adduct formation with zomepirac in the CD26-deficient mouse.

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P2860

P2860

Hepatic covalent adduct formation with zomepirac in the CD26-deficient mouse.

description

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type

label

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P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P50

P577

P5875

P698

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P50

P577

P5875

P698