Trimeric membrane-anchored gp41 inhibits HIV membrane fusion.
about
Viral and developmental cell fusion mechanisms: conservation and divergenceStructure of the HIV-1 gp41 Membrane-Proximal Ectodomain Region in a Putative Prefusion Conformation † , ‡A gp41 MPER-specific Llama VHH Requires a Hydrophobic CDR3 for Neutralization but not for Antigen RecognitionStructure of an HIV-1-neutralizing antibody target, the lipid-bound gp41 envelope membrane proximal region trimerBroad neutralization of human immunodeficiency virus type 1 (HIV-1) elicited from human rhinoviruses that display the HIV-1 gp41 ELDKWA epitopeBinding of anti-membrane-proximal gp41 monoclonal antibodies to CD4-liganded and -unliganded human immunodeficiency virus type 1 and simian immunodeficiency virus virionsNeutralizing epitopes in the membrane-proximal external region of HIV-1 gp41 are influenced by the transmembrane domain and the plasma membrane.In vivo and in vitro escape from neutralizing antibodies 2G12, 2F5, and 4E10.Antibodies generated in cats by a lipopeptide reproducing the membrane-proximal external region of the feline immunodeficiency virus transmembrane enhance virus infectivity.The membrane-proximal external region of the human immunodeficiency virus type 1 envelope: dominant site of antibody neutralization and target for vaccine designProtein-driven membrane stresses in fusion and fission.Immunogenicity of recombinant human immunodeficiency virus type 1-like particles expressing gp41 derivatives in a pre-fusion stateRole of lipid structure in the humoral immune response in mice to covalent lipid-peptides from the membrane proximal region of HIV-1 gp41.Transcytosis-blocking abs elicited by an oligomeric immunogen based on the membrane proximal region of HIV-1 gp41 target non-neutralizing epitopes.The cholesterol-binding motif of the HIV-1 glycoprotein gp41 regulates lateral sorting and oligomerization.Hepatitis B virus surface antigen assembly function persists when entire transmembrane domains 1 and 3 are replaced by a heterologous transmembrane sequence.Fusion Stage of HIV-1 Entry Depends on Virus-Induced Cell Surface Exposure of Phosphatidylserine.Membrane-anchored inhibitory peptides capture human immunodeficiency virus type 1 gp41 conformations that engage the target membrane prior to fusion.Development and immunological assessment of VLP-based immunogens exposing the membrane-proximal region of the HIV-1 gp41 protein.A botulinum neurotoxin-like function of Potentilla chinensis extract that inhibits neuronal SNARE complex formation, membrane fusion, neuroexocytosis, and muscle contraction.
P2860
Q24631787-C75F447D-6F45-4C81-82B7-C62008D482BBQ27653846-3A7A6C1C-FF22-4A00-A865-C36D3E03E304Q27676864-DF74E311-00EC-421E-BE07-9AC9443D2ACAQ27681501-05B22AFB-8B39-4FAC-BC1B-915DB9BDC676Q33417195-E172CA26-35E2-483E-BA84-BDBA4549D744Q35689608-35600B9D-4FD0-4549-9327-21668EEAB5BCQ35826306-18B1F046-0F92-43B5-BED8-5EE530515104Q35947769-6B738FAE-7F3C-4DA8-A49C-30972B1B64CFQ36097111-CDA37283-3311-4208-A938-FD63DE1836D1Q36497712-52A34A4F-B222-48CE-B225-F34C9E3A3595Q36566327-F0F69E58-5C61-40B6-95CC-14BEDE05B985Q37250899-5B6DA84E-0547-4C62-8FD2-460F0FC5B166Q37316019-82D85167-3009-4F88-8AFF-7DFD310467D5Q37348636-FBB12159-E502-414C-9E88-6B915ABC6693Q38993416-62FBEBCD-CB66-41DC-873B-CB0BCBC71B12Q39617158-D098A0C6-C3E1-4959-8F7C-ACA0DA88A6D6Q40124025-502AC586-D59D-48E6-89C3-CAA4F982A2D6Q40304999-C62E9995-BE60-4D7A-8C9E-1204E83A44C6Q42197619-15D46D9C-1E05-438A-964C-1772CDBDF4EEQ53152149-A226E2C6-73E8-476B-9B2E-F5CD0B6DF43F
P2860
Trimeric membrane-anchored gp41 inhibits HIV membrane fusion.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
@zh-hant
name
Trimeric membrane-anchored gp41 inhibits HIV membrane fusion.
@en
Trimeric membrane-anchored gp41 inhibits HIV membrane fusion.
@nl
type
label
Trimeric membrane-anchored gp41 inhibits HIV membrane fusion.
@en
Trimeric membrane-anchored gp41 inhibits HIV membrane fusion.
@nl
prefLabel
Trimeric membrane-anchored gp41 inhibits HIV membrane fusion.
@en
Trimeric membrane-anchored gp41 inhibits HIV membrane fusion.
@nl
P2093
P2860
P356
P1476
Trimeric membrane-anchored gp41 inhibits HIV membrane fusion
@en
P2093
Andreas Wagner
Gabriela Stiegler
Matthias T Dittmar
Oliver Lenz
Winfried Weissenhorn
P2860
P304
P356
10.1074/JBC.M411088200
P407
P577
2004-12-01T00:00:00Z