The HMG-CoA reductase inhibitor, atorvastatin, promotes a Th2 bias and reverses paralysis in central nervous system autoimmune disease.
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Oral high-dose atorvastatin treatment in relapsing-remitting multiple sclerosisAtorvastatin added to interferon beta for relapsing multiple sclerosis: 12-month treatment extension of the randomized multicenter SWABIMS trialStatins for multiple sclerosisStatins for multiple sclerosisStatins for multiple sclerosisInterferon-gamma induces major histocompatibility class II transactivator (CIITA), which mediates collagen repression and major histocompatibility class II activation by human aortic smooth muscle cellsPleiotropic effects of statinsThe bisphosphonate acute phase response: rapid and copious production of proinflammatory cytokines by peripheral blood gd T cells in response to aminobisphosphonates is inhibited by statinsThe "Statinth" wonder of the world: a panacea for all illnesses or a bubble about to burst.N-acetyl-L-cysteine ameliorates the inflammatory disease process in experimental autoimmune encephalomyelitis in Lewis ratsDo the pleiotropic effects of statins in the vasculature predict a role in inflammatory diseases?Put your heart into the joint benefits of statins!TCR Signal Strength Alters T-DC Activation and Interaction Times and Directs the Outcome of DifferentiationMacrophage Heterogeneity and Plasticity: Impact of Macrophage Biomarkers on AtherosclerosisT cell metabolism drives immunityCell Fusion along the Anterior-Posterior Neuroaxis in Mice with Experimental Autoimmune EncephalomyelitisCurrent and Emerging Uses of Statins in Clinical Therapeutics: A ReviewRegulation of Adaptive Immunity in Health and Disease by Cholesterol MetabolismMicrobial isoprenoid biosynthesis and human gammadelta T cell activationOngoing clinical trials of the pleiotropic effects of statinsStatins reduce the neurofibrillary tangle burden in a mouse model of tauopathyStatin therapy and autoimmune disease: from protein prenylation to immunomodulationAstrocytes in multiple sclerosis: a product of their environmentThe blood-brain-barrier in multiple sclerosis: functional roles and therapeutic targetingIron behaving badly: inappropriate iron chelation as a major contributor to the aetiology of vascular and other progressive inflammatory and degenerative diseasesPharmacological prion protein silencing accelerates central nervous system autoimmune disease via T cell receptor signallingMHC2TA is associated with differential MHC molecule expression and susceptibility to rheumatoid arthritis, multiple sclerosis and myocardial infarctionImproved preservation of residual beta cell function by atorvastatin in patients with recent onset type 1 diabetes and high CRP levels (DIATOR trial)Residual beta cell function in newly diagnosed type 1 diabetes after treatment with atorvastatin: the Randomized DIATOR TrialActivation of PPAR-γ and PTEN cascade participates in lovastatin-mediated accelerated differentiation of oligodendrocyte progenitor cells.p21-dependent inhibition of colon cancer cell growth by mevastatin is independent of inhibition of G1 cyclin-dependent kinases.New tricks for old dogs: countering antibiotic resistance in tuberculosis with host-directed therapeuticsA large Rab GTPase encoded by CRACR2A is a component of subsynaptic vesicles that transmit T cell activation signals.Statin treatment in multiple sclerosis: a systematic review and meta-analysis.Emerging therapies in multiple sclerosis.Importance of microbial natural products and the need to revitalize their discovery.The effects of atorvastatin in experimental autoimmune uveitisTREM2-transduced myeloid precursors mediate nervous tissue debris clearance and facilitate recovery in an animal model of multiple sclerosis.Transient decrease in circulating dendritic cell precursors after acute stroke: potential recruitment into the brain.Effect of HMG-CoA reductase inhibitors on activation of human gammadeltaT cells induced by Mycobacterium tuberculosis antigens.
P2860
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P2860
The HMG-CoA reductase inhibitor, atorvastatin, promotes a Th2 bias and reverses paralysis in central nervous system autoimmune disease.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh-hant
name
The HMG-CoA reductase inhibito ...... ous system autoimmune disease.
@en
The HMG-CoA reductase inhibito ...... ous system autoimmune disease.
@nl
type
label
The HMG-CoA reductase inhibito ...... ous system autoimmune disease.
@en
The HMG-CoA reductase inhibito ...... ous system autoimmune disease.
@nl
prefLabel
The HMG-CoA reductase inhibito ...... ous system autoimmune disease.
@en
The HMG-CoA reductase inhibito ...... ous system autoimmune disease.
@nl
P2093
P356
P1433
P1476
The HMG-CoA reductase inhibito ...... ous system autoimmune disease.
@en
P2093
Dennis J Mitchell
Eun Mi Hur
Jennifer L Radosevich
Juan C Patarroyo
Lawrence Steinman
Manuel Bravo
Pedro J Ruiz
Raymond A Sobel
Sawsan Youssef
Scott S Zamvil
P2888
P356
10.1038/NATURE01158
P407
P50
P577
2002-11-01T00:00:00Z
P5875
P6179
1001566151