Synthesis and characterization of oligodeoxynucleotides containing formamidopyrimidine lesions and nonhydrolyzable analogues.
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Excision of formamidopyrimidine lesions by endonucleases III and VIII is not a major DNA repair pathway in Escherichia coliThe formamidopyrimidines: purine lesions formed in competition with 8-oxopurines from oxidative stressSolution Structure of Duplex DNA Containing a β-Carba-Fapy-dG LesionBiological properties of single chemical-DNA adducts: a twenty year perspectiveReactive oxygen species (ROS) inducible DNA cross-linking agents and their effect on cancer cells and normal lymphocytes.Accumulation of true single strand breaks and AP sites in base excision repair deficient cellsMolecular mechanics parameters for the FapydG DNA lesionGenetic effects of oxidative DNA damages: comparative mutagenesis of the imidazole ring-opened formamidopyrimidines (Fapy lesions) and 8-oxo-purines in simian kidney cells.Mutagenic potentials of damaged nucleic acids produced by reactive oxygen/nitrogen species: approaches using synthetic oligonucleotides and nucleotides: survey and summaryNovel post-synthetic generation, isomeric resolution, and characterization of Fapy-dG within oligodeoxynucleotides: differential anomeric impacts on DNA duplex propertiesSynthesis, DNA polymerase incorporation, and enzymatic phosphate hydrolysis of formamidopyrimidine nucleoside triphosphates.Hydrogen peroxide inducible DNA cross-linking agents: targeted anticancer prodrugs.Sequence-dependent variation in the reactivity of 8-Oxo-7,8-dihydro-2'-deoxyguanosine toward oxidation.DNA damage by C1027 involves hydrogen atom abstraction and addition to nucleobases.ROS-inducible DNA cross-linking agent as a new anticancer prodrug building block.Chemical synthesis of oligonucleotides containing damaged bases for biological studies.DNA polymerase bypass in vitro and in E. coli of a C-nucleotide analogue of Fapy-dG.Efficient removal of formamidopyrimidines by 8-oxoguanine glycosylases.Interstrand cross-link formation in duplex and triplex DNA by modified pyrimidinesRegulation of DNA glycosylases and their role in limiting disease.Nucleophilic addition to silyl-protected five-membered ring oxocarbenium ions governed by stereoelectronic effects.Biologically relevant oxidants and terminology, classification and nomenclature of oxidatively generated damage to nucleobases and 2-deoxyribose in nucleic acids.An overview of chemical processes that damage cellular DNA: spontaneous hydrolysis, alkylation, and reactions with radicals.The leaving group strongly affects H₂O₂-induced DNA cross-linking by arylboronates.Harmonising measurements of 8-oxo-7,8-dihydro-2'-deoxyguanosine in cellular DNA and urine.Chemical and biological consequences of oxidatively damaged guanine in DNA.DNA sequence context as a determinant of the quantity and chemistry of guanine oxidation produced by hydroxyl radicals and one-electron oxidants.Syntheses of new spirocarbocyclic nucleoside analogs using iminonitroso Diels-Alder reactions.D-Arabinose-based synthesis of homo-C-d4T and homo-C-thymidine.Aromatic nitrogen mustard-based prodrugs: activity, selectivity, and the mechanism of DNA cross-linking.Free terminal amines in DNA-binding peptides alter the product distribution from guanine radicals produced by single electron oxidation.Synthetic studies on formamidopyrimidines related to clofarabine.Error-prone replication bypass of the imidazole ring-opened formamidopyrimidine deoxyguanosine adduct.Guanine-thymine intrastrand cross-linked lesion containing oligonucleotides: from chemical synthesis to in vitro enzymatic replication.
P2860
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P2860
Synthesis and characterization of oligodeoxynucleotides containing formamidopyrimidine lesions and nonhydrolyzable analogues.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh-hant
name
Synthesis and characterization ...... and nonhydrolyzable analogues.
@en
Synthesis and characterization ...... and nonhydrolyzable analogues.
@nl
type
label
Synthesis and characterization ...... and nonhydrolyzable analogues.
@en
Synthesis and characterization ...... and nonhydrolyzable analogues.
@nl
prefLabel
Synthesis and characterization ...... and nonhydrolyzable analogues.
@en
Synthesis and characterization ...... and nonhydrolyzable analogues.
@nl
P2093
P356
P1476
Synthesis and characterization ...... and nonhydrolyzable analogues.
@en
P2093
Aruna Sambandam
Carissa J Wiederholt
Kazuhiro Haraguchi
Marc M Greenberg
Michael O Delaney
Zsolt Hantosi
P304
P356
10.1021/JA012135Q
P407
P577
2002-04-01T00:00:00Z