about
Attenuation of acute rejection in a rat liver transplantation model by a liver-targeted dextran prodrug of methylprednisolone.Recent trends in the use of polysaccharides for improved delivery of therapeutic agents: pharmacokinetic and pharmacodynamic perspectives.Stereoselectivity in the pharmacodynamics and pharmacokinetics of the chiral antimalarial drugs.Effects of methylprednisolone and its liver-targeted dextran prodrug on ischemia-reperfusion injury in a rat liver transplantation model.Synthesis and in vitro characterization of novel dextran-methylprednisolone conjugates with peptide linkers: effects of linker length on hydrolytic and enzymatic release of methylprednisolone and its peptidyl intermediates.Rate and extent of drug accumulation after multiple dosing revisited.Effects of hepatic ischemia-reperfusion injury on the blood-brain barrier permeability to [(14)C] and [(13)C]sucrose.Evaluation of [14C] and [13C]Sucrose as Blood-Brain Barrier Permeability Markers.Metabolic bioactivation and toxicity of ethyl 4-hydroxybenzoate in human SK-MEL-28 melanoma cells.Human pharmacokinetics of ibuprofen enantiomers following different doses and formulations: intestinal chiral inversion.Development and application of an isolated perfused rat liver model to study the stimulation and inhibition of tumor necrosis factor-alpha production ex vivo.Effects of transient overexpression or knockdown of cytochrome P450 reductase on reactive oxygen species generation and hypoxia reoxygenation injury in liver cells.Cytochrome P450 induction by phenobarbital exacerbates warm hepatic ischemia-reperfusion injury in rat livers.Dextran-methylprednisolone succinate as a prodrug of methylprednisolone: dose-dependent pharmacokinetics in rats.Dextran-methylprednisolone succinate as a prodrug of methylprednisolone: plasma and tissue disposition.High-performance liquid chromatographic analysis of cyclosporin A in rat blood and liver using a commercially available internal standard.Effects of short-term portacaval anastomosis on the peripheral and brain disposition of the blood-brain barrier permeability marker sodium fluorescein in rats.Microsomal cytochrome P450 levels and activities of isolated rat livers perfused with albumin.Dextran-methylprednisolone succinate as a prodrug of methylprednisolone: local immunosuppressive effects in liver after systemic administration to rats.Liquid chromatographic analysis of the enantiomeric impurities in various (+)-pseudoephedrine samples.Attenuation of Kupffer cell activation in cold-preserved livers after pretreatment of rats with methylprednisolone or its macromolecular prodrug.Fractional clearance for verapamil N-demethylation in the isolated rat liver preparation.Effects of duration of ischemia and donor pretreatment with methylprednisolone or its macromolecular prodrug on the disposition of indocyanine green in cold-preserved rat livers.Short-term inhibitory effects of nitric oxide on cytochrome P450-mediated drug metabolism: time dependency and reversibility profiles in isolated perfused rat livers.Apparent stereoselectivity in propafenone uptake by human and rat erythrocytes.Effects of cytochrome p450 inhibition by cimetidine on the warm hepatic ischemia-reperfusion injury in rats.Effects of P-glycoprotein and Mrp2 inhibitors on the hepatobiliary disposition of Rhodamine 123 and its glucuronidated metabolite in isolated perfused rat livers.Simultaneous UPLC-MS/MS analysis of two stable isotope labeled versions of sucrose in mouse plasma and brain samples as markers of blood-brain barrier permeability and brain vascular space.Enzyme-selective effects of nitric oxide on affinity and maximum velocity of various rat cytochromes P450.Protective effects of diallyl sulfide, a garlic constituent, on the warm hepatic ischemia-reperfusion injury in a rat model.Effects of atazanavir/ritonavir or fosamprenavir/ritonavir on the pharmacokinetics of rosuvastatin.Effects of hepatic ischemia-reperfusion injury on the P-glycoprotein activity at the liver canalicular membrane and blood-brain barrier determined by in vivo administration of rhodamine 123 in rats.Enantioselective determination of tramadol and its main phase I metabolites in human plasma by high-performance liquid chromatography.Synthesis, analysis, in vitro characterization, and in vivo disposition of a lamivudine-dextran conjugate for selective antiviral delivery to the liver.Simultaneous analysis of dextran-methylprednisolone succinate, methylprednisolone succinate, and methylprednisolone by size-exclusion chromatography.Effects of storage and homogenization methods on the hepatic recovery of dextrans determined by size-exclusion chromatography.Dose dependency of the kinetics of dextrans in rats: effects of molecular weight.Molecular weight dependent tissue accumulation of dextrans: in vivo studies in rats.Hepatic disposition and effects of nitric oxide donors: rapid and concentration-dependent reduction in the cytochrome P450-mediated drug metabolism in isolated perfused rat livers.Effects of Pringle maneuver and partial hepatectomy on the pharmacokinetics and blood-brain barrier permeability of sodium fluorescein in rats.
P50
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P50
description
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Reza Mehvar
@ast
Reza Mehvar
@en
Reza Mehvar
@es
Reza Mehvar
@nl
Reza Mehvar
@sl
type
label
Reza Mehvar
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Reza Mehvar
@en
Reza Mehvar
@es
Reza Mehvar
@nl
Reza Mehvar
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prefLabel
Reza Mehvar
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Reza Mehvar
@en
Reza Mehvar
@es
Reza Mehvar
@nl
Reza Mehvar
@sl
P106
P31
P496
0000-0002-1770-0391