Phosphorylation of human estrogen receptor alpha at serine 118 by two distinct signal transduction pathways revealed by phosphorylation-specific antisera.
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SPBP is a phosphoserine-specific repressor of estrogen receptor alpha.An alpha-fetoprotein-derived peptide reduces the uterine hyperplasia and increases the antitumour effect of tamoxifenPhosphorylation of estrogen receptor alpha serine 167 is predictive of response to endocrine therapy and increases postrelapse survival in metastatic breast cancer.Endocrinology and hormone therapy in breast cancer: new insight into estrogen receptor-alpha function and its implication for endocrine therapy resistance in breast cancerCooperating transcription factors mediate the function of estrogen receptorLoss of Rho GDIα and resistance to tamoxifen via effects on estrogen receptor αThe prolyl isomerase Pin1 acts synergistically with CDK2 to regulate the basal activity of estrogen receptor α in breast cancerERK-mediated NF-κB activation through ASIC1 in response to acidosisPathways to tamoxifen resistance.Identification of four novel phosphorylation sites in estrogen receptor alpha: impact on receptor-dependent gene expression and phosphorylation by protein kinase CK2.Both XPD alleles contribute to the phenotype of compound heterozygote xeroderma pigmentosum patients.The cyclin-like protein, SPY1, regulates the ERα and ERK1/2 pathways promoting tamoxifen resistance.Phosphorylation of steroidogenic factor 1 is mediated by cyclin-dependent kinase 7Essential role of endogenous prolactin and CDK7 in estrogen-induced upregulation of the prolactin receptor in breast cancer cellsIcariin protects against bone loss induced by oestrogen deficiency and activates oestrogen receptor-dependent osteoblastic functions in UMR 106 cells.Crosstalk between nicotine and estrogen-induced estrogen receptor activation induces α9-nicotinic acetylcholine receptor expression in human breast cancer cells.Corticosteroids: way upstreamp38 mitogen-activated protein kinase activates eNOS in endothelial cells by an estrogen receptor alpha-dependent pathway in response to black tea polyphenols.Oestrogen receptor-alpha regulates non-canonical Hedgehog-signalling in the mammary gland.Ron receptor tyrosine kinase activation confers resistance to tamoxifen in breast cancer cell linesNaringin improves bone properties in ovariectomized mice and exerts oestrogen-like activities in rat osteoblast-like (UMR-106) cells.Growth factor stimulation induces a distinct ER(alpha) cistrome underlying breast cancer endocrine resistanceActivation of central, but not peripheral, estrogen receptors is necessary for estradiol's anorexigenic effect in ovariectomized rats.Estrogen receptors alpha and beta in rat placenta: detection by RT-PCR, real time PCR and Western blotting.Application of phosphorylation site-specific antibodies to measure nuclear receptor signaling: characterization of novel phosphoantibodies for estrogen receptor alpha.Non-nuclear estrogen receptor signaling in the endothelium.The Coffey Lecture: steroidogenic enzyme inhibitors and hormone dependent cancerAromatase inhibitors and xenograft studies.The ovarian hormone estradiol plays a crucial role in the control of food intake in females.New insights into estrogen receptor function in human breast cancer.Headway in resistance to endocrine therapy in breast cancer.A role for estrogen receptor phosphorylation in the resistance to tamoxifen.Kinases and protein phosphorylation as regulators of steroid hormone actionActivation of estrogen receptor-alpha reduces aortic smooth muscle differentiationp38γ mitogen-activated protein kinase (MAPK) confers breast cancer hormone sensitivity by switching estrogen receptor (ER) signaling from classical to nonclassical pathway via stimulating ER phosphorylation and c-Jun transcription.The Effects of Estrogen Receptors' Antagonist on Brain Edema, Intracranial Pressure and Neurological Outcomes after Traumatic Brain Injury in Rat.The role of S6K1 in ER-positive breast cancer.Hedgehog Acyltransferase as a target in estrogen receptor positive, HER2 amplified, and tamoxifen resistant breast cancer cells.Clinical trials update: endocrine and biological therapy combinations in the treatment of breast cancer.Phosphorylation at serines 104 and 106 by Erk1/2 MAPK is important for estrogen receptor-alpha activity.
P2860
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P2860
Phosphorylation of human estrogen receptor alpha at serine 118 by two distinct signal transduction pathways revealed by phosphorylation-specific antisera.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh
2002年學術文章
@zh-hant
name
Phosphorylation of human estro ...... phorylation-specific antisera.
@en
Phosphorylation of human estro ...... phorylation-specific antisera.
@nl
type
label
Phosphorylation of human estro ...... phorylation-specific antisera.
@en
Phosphorylation of human estro ...... phorylation-specific antisera.
@nl
prefLabel
Phosphorylation of human estro ...... phorylation-specific antisera.
@en
Phosphorylation of human estro ...... phorylation-specific antisera.
@nl
P2093
P2860
P356
P1433
P1476
Phosphorylation of human estro ...... phorylation-specific antisera.
@en
P2093
Dongsheng Chen
Elinor Washbrook
Frances V Fuller-Pace
Gaynor J Bates
Jacqueline Taylor
Jean-Marc Egly
Naveed Sarwar
Paul E Pace
R Charles Coombes
Richard J Epstein
P2860
P2888
P304
P356
10.1038/SJ.ONC.1205420
P407
P577
2002-07-01T00:00:00Z