Analysis of the L116K variant of CooA, the heme-containing CO sensor, suggests the presence of an unusual heme ligand resulting in novel activity.
about
CO-sensing mechanismsDual roles of an E-helix residue, Glu167, in the transcriptional activator function of CooA.Functionally critical elements of CooA-related CO sensors.Heme displacement mechanism of CooA activation: mutational and Raman spectroscopic evidence.CO and NO bind to Fe(II) DiGeorge critical region 8 heme but do not restore primary microRNA processing activity.The role of the hydrophobic distal heme pocket of CooA in ligand sensing and response.Activation mechanism of the CO sensor CooA. Mutational and resonance Raman spectroscopic studies.The C-helix in CooA rolls upon CO binding to ferrous heme.Changing the ligand specificity of CooA, a highly specific heme-based CO sensor.
P2860
Q24562799-B7E89D2E-CD7D-4F44-AE7A-20B3907C40F5Q33726887-FCB7B8D3-ECC8-4D1D-AF6E-E8BBC5323C35Q36239761-6602CDBD-7D57-4C39-B7CD-CABD1AA7BEA5Q37373615-6C9297FC-788A-4DED-916E-789ECECF3E17Q39264165-15598B37-29BF-4C11-A014-762DD909E454Q44217986-C71B4A4A-9204-48DA-A58C-B1BE9846FE82Q44471603-A5EC463A-B09C-40C4-AFA9-77756A125154Q45028081-7DBC4CBE-7473-4DEF-B662-2FB8360EAA90Q45028099-4A5B75C1-5485-42C3-A2CE-28A093D48087
P2860
Analysis of the L116K variant of CooA, the heme-containing CO sensor, suggests the presence of an unusual heme ligand resulting in novel activity.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh
2002年學術文章
@zh-hant
name
Analysis of the L116K variant ...... d resulting in novel activity.
@en
Analysis of the L116K variant ...... d resulting in novel activity.
@nl
type
label
Analysis of the L116K variant ...... d resulting in novel activity.
@en
Analysis of the L116K variant ...... d resulting in novel activity.
@nl
prefLabel
Analysis of the L116K variant ...... d resulting in novel activity.
@en
Analysis of the L116K variant ...... d resulting in novel activity.
@nl
P2093
P2860
P356
P1476
Analysis of the L116K variant ...... d resulting in novel activity.
@en
P2093
Gary P Roberts
Judith N Burstyn
Marc V Thorsteinsson
Robert L Kerby
Robert W Clark
P2860
P304
33616-33623
P356
10.1074/JBC.M203684200
P407
P577
2002-07-16T00:00:00Z