Cyclooxygenase 2-dependent prostaglandin E2 modulates cartilage proteoglycan degradation in human osteoarthritis explants.
about
Contribution of H3K4 methylation by SET-1A to interleukin-1-induced cyclooxygenase 2 and inducible nitric oxide synthase expression in human osteoarthritis chondrocytesMembrane-associated prostaglandin E synthase-1 is upregulated by proinflammatory cytokines in chondrocytes from patients with osteoarthritisA current review of molecular mechanisms regarding osteoarthritis and painDifferential direct effects of cyclo-oxygenase-1/2 inhibition on proteoglycan turnover of human osteoarthritic cartilage: an in vitro studyMechanical compression of cartilage explants induces multiple time-dependent gene expression patterns and involves intracellular calcium and cyclic AMPShear and compression differentially regulate clusters of functionally related temporal transcription patterns in cartilage tissueA Novel Synthesized Sulfonamido-Based Gallate-JEZ-C as Potential Therapeutic Agents for OsteoarthritisEvidence for cyclooxygenase-2 association with caveolin-3 in primary cultured rat chondrocytesGenome-wide association scan identifies a prostaglandin-endoperoxide synthase 2 variant involved in risk of knee osteoarthritisRole of fibroblast growth factor 8 (FGF8) in animal models of osteoarthritis.Sphingosine-1-phosphate attenuates proteoglycan aggrecan expression via production of prostaglandin E2 from human articular chondrocytes.The role of inflammatory and anti-inflammatory cytokines in the pathogenesis of osteoarthritis.Dynamic loading enhances integrative meniscal repair in the presence of interleukin-1.Prostaglandin E2 induces interleukin-6 expression in human chondrocytes via cAMP/protein kinase A- and phosphatidylinositol 3-kinase-dependent NF-kappaB activation.Interleukin-6 synthesis in human chondrocytes is regulated via the antagonistic actions of prostaglandin (PG)E2 and 15-deoxy-Δ(12,14)-PGJ2.Endoplasmic reticulum stress (ER-stress) by 2-deoxy-D-glucose (2DG) reduces cyclooxygenase-2 (COX-2) expression and N-glycosylation and induces a loss of COX-2 activity via a Src kinase-dependent pathway in rabbit articular chondrocytes.Transforming growth factor-beta2 suppresses collagen cleavage in cultured human osteoarthritic cartilage, reduces expression of genes associated with chondrocyte hypertrophy and degradation, and increases prostaglandin E(2) production.Low-level laser therapy in IL-1β, COX-2, and PGE2 modulation in partially injured Achilles tendon.Effects of BIS076 in a model of osteoarthritis induced by anterior cruciate ligament transection in ovariectomised rats.Study of osteoarthritis treatment with anti-inflammatory drugs: cyclooxygenase-2 inhibitor and steroids.Long term NSAID treatment inhibits COX-2 synthesis in the knee synovial membrane of patients with osteoarthritis: differential proinflammatory cytokine profile between celecoxib and aceclofenacA prospective randomised multicentre study comparing continuous and intermittent treatment with celecoxib in patients with osteoarthritis of the knee or hip.Celecoxib: considerations regarding its potential disease-modifying properties in osteoarthritisEffects of short-term glucocorticoid treatment on changes in cartilage matrix degradation and chondrocyte gene expression induced by mechanical injury and inflammatory cytokines.Celecoxib can suppress expression of genes associated with PGE2 pathway in chondrocytes under inflammatory conditions.Therapeutic Effect of Chenodeoxycholic Acid in an Experimental Rabbit Model of OsteoarthritisInvolvement of the p38 MAPK-NF-kappaB signal transduction pathway and COX-2 in the pathobiology of meniscus degeneration in humansConnexin43 hemichannels mediate small molecule exchange between chondrocytes and matrix in biomechanically-stimulated temporomandibular joint cartilage.Standardized butanol fraction of WIN-34B suppresses cartilage destruction via inhibited production of matrix metalloproteinase and inflammatory mediator in osteoarthritis human cartilage explants culture and chondrocytes.Effect of Hijikia fusiforme extracts on degenerative osteoarthritis in vitro and in vivo models.Prostaglandin E2 and its cognate EP receptors control human adult articular cartilage homeostasis and are linked to the pathophysiology of osteoarthritisIntegrative repair of the meniscus: lessons from in vitro studies.A suppressive effect of prostaglandin E2 on the expression of SERPINE1/plasminogen activator inhibitor-1 in human articular chondrocytes: An in vitro pilot study.Conditioned media from adipose-tissue-derived mesenchymal stem cells downregulate degradative mediators induced by interleukin-1β in osteoarthritic chondrocytes.JNK activation is essential for activation of MEK/ERK signaling in IL-1β-induced COX-2 expression in synovial fibroblasts.Inhibitors of microsomal prostaglandin E2 synthase-1 enzyme as emerging anti-inflammatory candidates.TLR4 signalling in osteoarthritis--finding targets for candidate DMOADs.Effects of Dexamethasone Concentration and Timing of Exposure on Chondrogenesis of Equine Bone Marrow-Derived Mesenchymal Stem Cells.COX-2-selective NSAIDs and risk of hip or knee replacements: a population-based case-control study.Apoptosis signaling pathways in osteoarthritis and possible protective role of melatonin.
P2860
Q24300761-686C1650-7B6F-4C63-9A34-060C7B1F35A5Q24805523-477B35FB-DD43-44FD-8243-D6917C9601ECQ27023006-4FF37D05-2BFA-4780-8FEA-2BD7175FAF7AQ28193949-AF2C2AC4-ACCD-4D61-A171-9FCC4FB5EFF1Q28244888-B52F2606-DE7C-4479-9C4A-CA48DAE04955Q28246792-7F647D22-E07A-4E85-91B5-EA1D8CF8FFF7Q28548654-D82D464D-EFC4-45B5-A3A2-B55B7ACA90D6Q28577098-1429725C-DBFE-476E-B65A-483A2052045CQ28943498-A029324F-82CE-4DB2-ABB9-5791AAC8A265Q30492900-617A880D-8997-48B7-AEAE-994B1BBE1772Q33279463-B333AC71-D7CF-4C3A-99B1-742270849EACQ33614316-F8609C52-0694-4206-BD4E-3377A0E74D06Q33860663-F747E1D9-9901-4CC9-BBD1-C93342207D44Q33929745-EC8B6053-7A97-4846-B04B-E77E242DB1E2Q34077992-9006176E-2D54-42DC-A5E6-8302520D1F1AQ34355831-C348E777-F69B-4FE3-B00B-7AF37F304AFBQ35070721-55D32801-A138-4BEC-837E-FADD23B51BCFQ35214596-524E8079-C114-4C25-8C36-A782E9807516Q35530155-464AD33D-8576-4FE2-ABCE-BE5C40E5AC89Q35592094-E0CAEC78-CEA3-4318-9A8A-A20ECFE53449Q35637500-4DF7A640-6387-47C5-AB95-FBD55F85AF64Q35638355-7C1BD46B-5FCE-42B9-89C0-11E749738770Q35840709-F1D1B4BA-39D1-4EB6-A18E-E1B1BD32AB5FQ35840719-BA9F8307-250C-4549-9201-E3AC687D9A60Q36046336-41DB656F-D55B-4611-98B9-EF98E9E715D8Q36204519-3320163E-4959-4D53-A4A2-549AA33BD056Q36405454-D87F9FB6-771D-4692-88F2-4917729C98C7Q36446463-2EC63B66-7995-4284-BD2B-404E3FB060D3Q36574611-7D4B6DF2-B342-4477-8649-A1EB57089DBEQ36936823-44ACA163-9406-4508-BA6A-1FAC40F99003Q37137531-741661F5-CA97-43C9-8DD5-4CA8276A8351Q37310030-10725A77-E763-4C5E-971B-FFE368F6E760Q37358095-21AEE832-44FD-4C78-8CEA-DBCEF0E31E66Q37394547-CA5A6F18-9D92-4548-93D8-96B48DA4C390Q37560064-D67193D6-A9B6-4897-8511-E37F55723CBBQ38229056-FF455B5B-B6FD-404D-B15C-29778BBDA6F4Q38289811-315AADED-8A5B-4FC4-B72B-881AF2D1CF41Q38362150-6428E0EF-D4C9-4DC4-8327-485B02BF0E35Q38429953-1CDDF5A9-11CB-4240-A26F-9A95F02966F8Q38935714-760F2354-1961-4140-838A-1856A404F4AC
P2860
Cyclooxygenase 2-dependent prostaglandin E2 modulates cartilage proteoglycan degradation in human osteoarthritis explants.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh
2002年學術文章
@zh-hant
name
Cyclooxygenase 2-dependent pro ...... human osteoarthritis explants.
@en
Cyclooxygenase 2-dependent pro ...... human osteoarthritis explants.
@nl
type
label
Cyclooxygenase 2-dependent pro ...... human osteoarthritis explants.
@en
Cyclooxygenase 2-dependent pro ...... human osteoarthritis explants.
@nl
prefLabel
Cyclooxygenase 2-dependent pro ...... human osteoarthritis explants.
@en
Cyclooxygenase 2-dependent pro ...... human osteoarthritis explants.
@nl
P2093
P2860
P356
P1476
Cyclooxygenase 2-dependent pro ...... human osteoarthritis explants.
@en
P2093
Alane Koki
B Mark Woerner
Catherine S Tripp
Dorothy Edwards
Karen Seibert
Mark G Currie
Medora M Hardy
Pamela T Manning
P2860
P304
P356
10.1002/ART.10356
P577
2002-07-01T00:00:00Z