T7 DNA helicase: a molecular motor that processively and unidirectionally translocates along single-stranded DNA.
about
Active and passive mechanisms of helicasesSingle-molecule studies reveal dynamics of DNA unwinding by the ring-shaped T7 helicaseDynamic coupling between the motors of DNA replication: hexameric helicase, DNA polymerase, and primaseNS3 helicase actively separates RNA strands and senses sequence barriers ahead of the opening forkKinetic mechanism for single-stranded DNA binding and translocation by Saccharomyces cerevisiae Isw2.Kinetic model for the ATP-dependent translocation of Saccharomyces cerevisiae RSC along double-stranded DNA.Simulating the electrostatic guidance of the vectorial translocations in hexameric helicases and translocases.Hexameric helicase deconstructed: interplay of conformational changes and substrate couplingResidues in the central beta-hairpin of the DNA helicase of bacteriophage T7 are important in DNA unwinding.The protease domain increases the translocation stepping efficiency of the hepatitis C virus NS3-4A helicase.The DNA-unwinding mechanism of the ring helicase of bacteriophage T7.Mechanisms of helicases.Opening of nucleic-acid double strands by helicases: active versus passive opening.DNA unwinding and protein displacement by superfamily 1 and superfamily 2 helicases.Simultaneous amplification and screening of whole plasmids using the T7 bacteriophage replisome.Helicase-DNA polymerase interaction is critical to initiate leading-strand DNA synthesis.The glutamate switch of bacteriophage T7 DNA helicase: role in coupling nucleotide triphosphate (NTP) and DNA binding to NTP hydrolysis.Coupling dTTP hydrolysis with DNA unwinding by the DNA helicase of bacteriophage T7.Cooperative base pair melting by helicase and polymerase positioned one nucleotide from each other.Dda helicase tightly couples translocation on single-stranded DNA to unwinding of duplex DNA: Dda is an optimally active helicase.Helicase processivity and not the unwinding velocity exhibits universal increase with force.Heterohexamer of 56- and 63-kDa Gene 4 Helicase-Primase of Bacteriophage T7 in DNA Replication.An interaction between DNA polymerase and helicase is essential for the high processivity of the bacteriophage T7 replisome.Mechanisms of a ring shaped helicaseKinetic mechanism of DNA translocation by the RSC molecular motor.Coupling of DNA unwinding to nucleotide hydrolysis in a ring-shaped helicase.Switching from single-stranded to double-stranded DNA limits the unwinding processivity of ring-shaped T7 DNA helicaseFunctional interaction between the herpes simplex virus type 1 polymerase processivity factor and origin-binding proteins: enhancement of UL9 helicase activityDiscrete interactions between bacteriophage T7 primase-helicase and DNA polymerase drive the formation of a priming complex containing two copies of DNA polymerase.Experimental and computational analysis of DNA unwinding and polymerization kinetics.The arginine finger of bacteriophage T7 gene 4 helicase: role in energy coupling.Effect of single-stranded DNA-binding proteins on the helicase and primase activities of the bacteriophage T7 gene 4 protein.The macroscopic rate of nucleic acid translocation by hepatitis C virus helicase NS3h is dependent on both sugar and base moieties.Helicase and polymerase move together close to the fork junction and copy DNA in one-nucleotide steps.Processivity of nucleic acid unwinding and translocation by helicases.Promiscuous usage of nucleotides by the DNA helicase of bacteriophage T7: determinants of nucleotide specificity.The primary and secondary translocase activities within E. coli RecBC helicase are tightly coupled to ATP hydrolysis by the RecB motorDNA synthesis provides the driving force to accelerate DNA unwinding by a helicase.Discovery of hepatitis C virus NS3 helicase inhibitors by a multiplexed, high-throughput helicase activity assay based on graphene oxide.Nucleic acid unwinding by hepatitis C virus and bacteriophage t7 helicases is sensitive to base pair stability.
P2860
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P2860
T7 DNA helicase: a molecular motor that processively and unidirectionally translocates along single-stranded DNA.
description
2002 nî lūn-bûn
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2002年の論文
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2002年学术文章
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2002年学术文章
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2002年学术文章
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2002年学术文章
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name
T7 DNA helicase: a molecular m ...... tes along single-stranded DNA.
@en
T7 DNA helicase: a molecular m ...... tes along single-stranded DNA.
@nl
type
label
T7 DNA helicase: a molecular m ...... tes along single-stranded DNA.
@en
T7 DNA helicase: a molecular m ...... tes along single-stranded DNA.
@nl
prefLabel
T7 DNA helicase: a molecular m ...... tes along single-stranded DNA.
@en
T7 DNA helicase: a molecular m ...... tes along single-stranded DNA.
@nl
P1476
T7 DNA helicase: a molecular m ...... ates along single-stranded DNA
@en
P2093
Murli Narayan
Smita S Patel
P304
P356
10.1016/S0022-2836(02)00733-7
P407
P50
P577
2002-08-01T00:00:00Z