Cyclic nucleotide research -- still expanding after half a century.
about
Structure-guided design of selective Epac1 and Epac2 agonistsCyclic nucleotide binding proteins in the Arabidopsis thaliana and Oryza sativa genomesProtein kinase A phosphorylation of human phosphodiesterase 3B promotes 14-3-3 protein binding and inhibits phosphatase-catalyzed inactivationMdm2 directs the ubiquitination of beta-arrestin-sequestered cAMP phosphodiesterase-4D5An anchored PKA and PDE4 complex regulates subplasmalemmal cAMP dynamicsThe protein kinase A anchoring protein mAKAP coordinates two integrated cAMP effector pathways.Binding of cyclic nucleotides to phosphodiesterase 10A and 11A GAF domains does not stimulate catalytic activityOne hundred years of hormonesRolipram: a specific phosphodiesterase 4 inhibitor with potential antipsychotic activity.AKAP18 contains a phosphoesterase domain that binds AMPImpairment of LTD and cerebellar learning by Purkinje cell-specific ablation of cGMP-dependent protein kinase IPhosphodiesterase genes are associated with susceptibility to major depression and antidepressant treatment responseBiomarkers for sporadic Creutzfeldt-Jakob diseaseRegulatory T-Cell-Mediated Suppression of Conventional T-Cells and Dendritic Cells by Different cAMP Intracellular PathwaysThe cAMP Pathway as Therapeutic Target in Autoimmune and Inflammatory DiseasesGenetically-encoded tools for cAMP probing and modulation in living systemsCardiac cAMP: production, hydrolysis, modulation and detectionAlterations of cAMP-dependent signaling in dystrophic skeletal muscleRole of guanine-nucleotide exchange factor Epac in renal physiology and pathophysiologyCrosstalk between Mycobacterium tuberculosis and the host cell"cAMP sponge": a buffer for cyclic adenosine 3', 5'-monophosphateCrystal structure of the GAF-B domain from human phosphodiesterase 10A complexed with its ligand, cAMPSolution Structure of the cGMP Binding GAF Domain from Phosphodiesterase 5: INSIGHTS INTO NUCLEOTIDE SPECIFICITY, DIMERIZATION, AND cGMP-DEPENDENT CONFORMATIONAL CHANGEStructural basis for the catalytic mechanism of human phosphodiesterase 9Structural Basis for Cyclic-Nucleotide Selectivity and cGMP-Selective Activation of PKG IModulation of Compartmentalised Cyclic Nucleotide Signalling via Local Inhibition of Phosphodiesterase ActivityCharacterization of the MRP4- and MRP5-mediated transport of cyclic nucleotides from intact cellsHuman PDE4A8, a novel brain-expressed PDE4 cAMP-specific phosphodiesterase that has undergone rapid evolutionary changecAMP is a ligand for the tandem GAF domain of human phosphodiesterase 10 and cGMP for the tandem GAF domain of phosphodiesterase 11Upregulation of endothelial adhesion molecules by lysophosphatidylcholine. Involvement of G protein-coupled receptor GPR4FRET measurements of intracellular cAMP concentrations and cAMP analog permeability in intact cellsIdentification of Rare Variants in ATP8B4 as a Risk Factor for Systemic Sclerosis by Whole-Exome Sequencing.CbpA: a polarly localized novel cyclic AMP-binding protein in Pseudomonas aeruginosaAn entirely specific type I A-kinase anchoring protein that can sequester two molecules of protein kinase A at mitochondriaCatalytic activity of cGMP-dependent protein kinase type I in intact cells is independent of N-terminal autophosphorylationOccurrence of A-kinase anchor protein and associated cAMP-dependent protein kinase in the inner compartment of mammalian mitochondriaAttenuation of the activity of the cAMP-specific phosphodiesterase PDE4A5 by interaction with the immunophilin XAP2Cyclic nucleotide phosphodiesterase 1A: a key regulator of cardiac fibroblast activation and extracellular matrix remodeling in the heartbeta-Arrestin-mediated PDE4 cAMP phosphodiesterase recruitment regulates beta-adrenoceptor switching from Gs to GiExchange protein activated by cAMP (Epac) mediates cAMP-dependent but protein kinase A-insensitive modulation of vascular ATP-sensitive potassium channels
P2860
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P2860
Cyclic nucleotide research -- still expanding after half a century.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh
2002年學術文章
@zh-hant
name
Cyclic nucleotide research -- still expanding after half a century.
@en
Cyclic nucleotide research -- still expanding after half a century.
@nl
type
label
Cyclic nucleotide research -- still expanding after half a century.
@en
Cyclic nucleotide research -- still expanding after half a century.
@nl
prefLabel
Cyclic nucleotide research -- still expanding after half a century.
@en
Cyclic nucleotide research -- still expanding after half a century.
@nl
P2860
P356
P1476
Cyclic nucleotide research -- still expanding after half a century.
@en
P2093
Joseph A Beavo
Laurence L Brunton
P2860
P2888
P304
P356
10.1038/NRM911
P577
2002-09-01T00:00:00Z
P5875
P6179
1002577496