Minocycline slows disease progression in a mouse model of amyotrophic lateral sclerosis.
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Progressive changes in microglia and macrophages in spinal cord and peripheral nerve in the transgenic rat model of amyotrophic lateral sclerosisMuscle atrophy and motor neuron degeneration in human NEDL1 transgenic miceMinocycline attenuates microglial activation but fails to mitigate striatal dopaminergic neurotoxicity: role of tumor necrosis factor- alphaMinocycline for amyotrophic lateral sclerosis or motor neuron diseaseTherapeutic vaccine for acute and chronic motor neuron diseases: implications for amyotrophic lateral sclerosis.Low dose intravenous minocycline is neuroprotective after middle cerebral artery occlusion-reperfusion in ratsTherapeutic neuroprotective agents for amyotrophic lateral sclerosisDesign, power, and interpretation of studies in the standard murine model of ALSDeletion of the hemopexin or heme oxygenase-2 gene aggravates brain injury following stroma-free hemoglobin-induced intracerebral hemorrhageA randomized, double blind, placebo-controlled trial of pioglitazone in combination with riluzole in amyotrophic lateral sclerosisMechanisms underlying inflammation in neurodegenerationThe Protective Effect of Minocycline in a Paraquat-Induced Parkinson's Disease Model in Drosophila is Modified in Altered Genetic Backgrounds.Murine models of acute neuronopathic Gaucher disease.Aging in individuals with the FMR1 mutation.Critical data-based re-evaluation of minocycline as a putative specific microglia inhibitor.Proteasomes remain intact, but show early focal alteration in their composition in a mouse model of amyotrophic lateral sclerosis.Adaptive immune neuroprotection in G93A-SOD1 amyotrophic lateral sclerosis mice.Side effects of minocycline treatment in patients with fragile X syndrome and exploration of outcome measuresInflammation in ALS and SMA: sorting out the good from the evil.Redox modifier genes and pathways in amyotrophic lateral sclerosis.Modelling amyotrophic lateral sclerosis: progress and possibilitiesA novel target of action of minocycline in NGF-induced neurite outgrowth in PC12 cells: translation initiation [corrected] factor eIF4AI.Spinal but not cortical microglia acquire an atypical phenotype with high VEGF, galectin-3 and osteopontin, and blunted inflammatory responses in ALS rats.Reductions in amyloid-beta-derived neuroinflammation, with minocycline, restore cognition but do not significantly affect tau hyperphosphorylation.Minocycline inhibition of monocyte activation correlates with neuronal protection in SIV neuroAIDSAccelerated clinical discovery using self-reported patient data collected online and a patient-matching algorithm.Stem cell-derived motor neurons: applications and challenges in amyotrophic lateral sclerosis.Neurotrophic growth factors for the treatment of amyotrophic lateral sclerosis: where do we stand?Peripheral hyperstimulation alters site of disease onset and course in SOD1 ratsA comparison of in vitro properties of resting SOD1 transgenic microglia reveals evidence of reduced neuroprotective functionAdaptive immune regulation of glial homeostasis as an immunization strategy for neurodegenerative diseasesCatalytic antioxidants and neurodegenerationMicroglial activation correlates with disease progression and upper motor neuron clinical symptoms in amyotrophic lateral sclerosisGenetic rodent models of amyotrophic lateral sclerosisMinocycline causes widespread cell death and increases microglial labeling in the neonatal mouse brain.Minocycline neuroprotects, reduces microglial activation, inhibits caspase 3 induction, and viral replication following Japanese encephalitis.Dual transplantation of human neural stem cells into cervical and lumbar cord ameliorates motor neuron disease in SOD1 transgenic rats.Motor neuron trophic factors: therapeutic use in ALS?Medical management of Parkinson's disease: focus on neuroprotectionMinocycline upregulates pro-survival genes and downregulates pro-apoptotic genes in experimental glaucoma.
P2860
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P2860
Minocycline slows disease progression in a mouse model of amyotrophic lateral sclerosis.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh-hant
name
Minocycline slows disease progression in a mouse model of amyotrophic lateral sclerosis.
@en
Minocycline slows disease progression in a mouse model of amyotrophic lateral sclerosis.
@nl
type
label
Minocycline slows disease progression in a mouse model of amyotrophic lateral sclerosis.
@en
Minocycline slows disease progression in a mouse model of amyotrophic lateral sclerosis.
@nl
prefLabel
Minocycline slows disease progression in a mouse model of amyotrophic lateral sclerosis.
@en
Minocycline slows disease progression in a mouse model of amyotrophic lateral sclerosis.
@nl
P2093
P356
P1476
Minocycline slows disease progression in a mouse model of amyotrophic lateral sclerosis.
@en
P2093
Jasna Kriz
Jean-Pierre Julien
Minh Dang Nguyen
P304
P356
10.1006/NBDI.2002.0487
P577
2002-08-01T00:00:00Z