Thermostabilization of recombinant human and bovine CuZn superoxide dismutases by replacement of free cysteines.
about
Superoxide dismutase from the eukaryotic thermophile Alvinella pompejana: structures, stability, mechanism, and insights into amyotrophic lateral sclerosisZinc binding modulates the entire folding free energy surface of human Cu,Zn superoxide dismutase.Role of the dimeric structure in Cu,Zn superoxide dismutase. pH-dependent, reversible denaturation of the monomeric enzyme from Escherichia coli.Function of the Greek key connection analysed using circular permutants of superoxide dismutase.Loss of metal ions, disulfide reduction and mutations related to familial ALS promote formation of amyloid-like aggregates from superoxide dismutase.Metal-free ALS variants of dimeric human Cu,Zn-superoxide dismutase have enhanced populations of monomeric speciesCopper-based pulsed dipolar ESR spectroscopy as a probe of protein conformation linked to disease states.Aggregation propensities of superoxide dismutase G93 hotspot mutants mirror ALS clinical phenotypesDisulfide-reduced ALS variants of Cu, Zn superoxide dismutase exhibit increased populations of unfolded species.The structural biochemistry of the superoxide dismutases.Developing master keys to brain pathology, cancer and aging from the structural biology of proteins controlling reactive oxygen species and DNA repair.Superoxide dismutase as a novel macromolecular nitric oxide carrier: preparation and characterization.Enthalpic barriers dominate the folding and unfolding of the human Cu, Zn superoxide dismutase monomerThe role of thiols and disulfides on protein stability.Amsacta moorei entomopoxvirus expresses an active superoxide dismutase.Different immunoreactivity against monoclonal antibodies between wild-type and mutant copper/zinc superoxide dismutase linked to amyotrophic lateral sclerosis.The molecular mechanism of the termination of insect diapause, part 1: A timer protein, TIME-EA4, in the diapause eggs of the silkworm Bombyx mori is a metallo-glycoprotein.Amino acid substitutions enhancing thermostability of Bacillus polymyxa beta-glucosidase AModification of cysteine 111 in Cu/Zn superoxide dismutase results in altered spectroscopic and biophysical properties.Human SOD1 before harboring the catalytic metal: solution structure of copper-depleted, disulfide-reduced form.Calorimetric analysis of thermodynamic stability and aggregation for apo and holo amyotrophic lateral sclerosis-associated Gly-93 mutants of superoxide dismutase.Oxidative modification to cysteine sulfonic acid of Cys111 in human copper-zinc superoxide dismutase.Expression of Cu/Zn and Mn superoxide dismutases during bovine embryo development: influence of in vitro culture.
P2860
Q27653085-BE3C382E-30EA-4195-B223-ECA931B749FBQ30157502-1E08C33C-FFF4-49D7-82C2-7017D0D35A93Q30176259-46C6A431-4AFE-4657-A281-ACBAEAA1DEFAQ30176552-B8604631-3FAE-4F77-A355-5C0FA3E4C035Q33423010-BAC7DF51-F679-4037-A1B5-E64D0ABB4C79Q33559671-D36B9EF8-7C05-40D7-9EB2-984A5E8B0D82Q34310311-6D9701C8-088A-4E95-94CE-CB26C3BCA965Q34442177-68EE8976-3A58-46BE-B0F8-7236F13619D1Q34788369-8288966B-AB6E-4407-9F90-FF0C369912A8Q34993111-C237C308-14BE-430B-BAE5-357391C7F3C3Q35865533-BDFFED22-76F9-425D-9604-4352447C1111Q36432414-3114917B-4737-4B9B-A265-B36ED8AC4A78Q37017713-E1633EAC-3511-4BFF-A2AF-8A5B47760632Q37524089-FED7005C-2414-4427-A5A8-8EE128FB62CBQ39991443-5538AD3F-1941-4BAA-9027-0A170AE7F1B3Q40496567-E4E09E6E-A08E-45DE-AA58-593ABEEB5C79Q42036160-8CFC6997-C920-4BC7-9630-8C800226FE50Q42040643-6EF77EF6-03CB-49BF-9DCA-E53A5D1310F9Q42128442-BCF87BF8-5C48-4CCC-A04B-2AB00591FEC7Q46807674-603F28D3-E848-4023-8470-1C031861837EQ46890321-AD32A3A5-3ECA-40D7-8A1E-1FBC13197374Q46968887-6E6E5606-ABA3-4744-A3C6-98DAEEC6F8DDQ50720034-23F800EA-21FF-497F-A6C9-F60D06E6C98E
P2860
Thermostabilization of recombinant human and bovine CuZn superoxide dismutases by replacement of free cysteines.
description
1991 nî lūn-bûn
@nan
1991年の論文
@ja
1991年学术文章
@wuu
1991年学术文章
@zh
1991年学术文章
@zh-cn
1991年学术文章
@zh-hans
1991年学术文章
@zh-my
1991年学术文章
@zh-sg
1991年學術文章
@yue
1991年學術文章
@zh-hant
name
Thermostabilization of recombi ...... replacement of free cysteines.
@en
Thermostabilization of recombi ...... replacement of free cysteines.
@nl
type
label
Thermostabilization of recombi ...... replacement of free cysteines.
@en
Thermostabilization of recombi ...... replacement of free cysteines.
@nl
prefLabel
Thermostabilization of recombi ...... replacement of free cysteines.
@en
Thermostabilization of recombi ...... replacement of free cysteines.
@nl
P2093
P1476
Thermostabilization of recombi ...... replacement of free cysteines.
@en
P2093
C Gallegos
D E Cabelli
E D Getzoff
G T Mullenbach
J A Tainer
P Tekamp-Olson
R A Hallewell
P304
P356
10.1016/S0006-291X(05)81443-3
P407
P577
1991-11-01T00:00:00Z