Structure-activity studies of 14-helical antimicrobial beta-peptides: probing the relationship between conformational stability and antimicrobial potency.
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Peptide-Like Molecules (PLMs): A Journey from Peptide Bond Isosteres to Gramicidin S Mimetics and Mitochondrial Targeting Agents.Hydrophobicity of Antifungal β-Peptides Is Associated with Their Cytotoxic Effect on In Vitro Human Colon Caco-2 and Liver HepG2 CellsStructural similarity between β(3)-peptides synthesized from β(3)-homo-amino acids and aspartic acid monomers.Biophysical and structural characterization of a robust octameric beta-peptide bundleBiomolecular engineering by combinatorial design and high-throughput screening: small, soluble peptides that permeabilize membranes.Comparison of design strategies for promotion of beta-peptide 14-helix stability in water.High-resolution structure of a beta-peptide bundle.Inhibiting HIV fusion with a beta-peptide foldamer.Hydrophobicity and helicity regulate the antifungal activity of 14-helical β-peptides.Positional screening and NMR structure determination of side-chain-to-side-chain cyclized β3-peptides.Polyelectrolyte multilayers fabricated from antifungal β-peptides: design of surfaces that exhibit antifungal activity against Candida albicansPolymer multilayers loaded with antifungal β-peptides kill planktonic Candida albicans and reduce formation of fungal biofilms on the surfaces of flexible catheter tubes.Synthesis, biophysical, and pharmacological evaluation of the melanocortin agonist AST3-88: modifications of peptide backbone at Trp 7 position lead to a potent, selective, and stable ligand of the melanocortin 4 receptor (MC4R).Synthetic polymers active against Clostridium difficile vegetative cell growth and spore outgrowthProbing Membrane Insertion Activity of Antimicrobial Polymers via Coarse-grain Molecular DynamicsAntifungal Activity of 14-Helical β-Peptides against Planktonic Cells and Biofilms of Candida SpeciesInfectious Disease: Connecting Innate Immunity to Biocidal Polymers.Correlating antimicrobial activity and model membrane leakage induced by nylon-3 polymers and detergentsNylon-3 polymers with selective antifungal activityDe novo designed synthetic mimics of antimicrobial peptides.Peptide design for antimicrobial and immunomodulatory applications.Antimicrobial β-peptides and α-peptoids.Stabilized helical peptides: overview of the technologies and therapeutic promises.Recent development of small antimicrobial peptidomimetics.Combating multidrug-resistant bacteria: current strategies for the discovery of novel antibacterials.An overview of peptide and peptoid foldamers in medicinal chemistry.Structure-activity relationships among antifungal nylon-3 polymers: identification of materials active against drug-resistant strains of Candida albicans.Inhibition of herpes simplex virus type 1 infection by cationic beta-peptides.Beyond conventional antibiotics - New directions for combination products to combat biofilm.Comparison of NMR structures and model-membrane interactions of 15-residue antimicrobial peptides derived from bovine lactoferricin.Antifungal activity of a β-peptide in synthetic urine media: Toward materials-based approaches to reducing catheter-associated urinary tract fungal infections.Helical-ribbon formation by a beta-amino acid modified amyloid beta-peptide fragment.Effects of Cyclic vs. Acyclic Hydrophobic Subunits on the Chemical Structure and Biological Properties of Nylon-3 Co-Polymers.α-Helix mimicry with α/β-peptides.Serum stabilities of short tryptophan- and arginine-rich antimicrobial peptide analogs.Characteristic structural parameters for the γ-peptide 14-helix: importance of subunit preorganizationInfluence of lipid composition on membrane activity of antimicrobial phenylene ethynylene oligomers.Consequences of isostructural main-chain modifications for the design of antimicrobial foldamers: helical mimics of host-defense peptides based on a heterogeneous amide/urea backbone.β(3R3)-Peptides: design and synthesis of novel peptidomimetics and their self-assembling properties at the air-water interface.Cytoplasmic and nuclear delivery of a TAT-derived peptide and a beta-peptide after endocytic uptake into HeLa cells.
P2860
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P2860
Structure-activity studies of 14-helical antimicrobial beta-peptides: probing the relationship between conformational stability and antimicrobial potency.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh-hant
name
Structure-activity studies of ...... ity and antimicrobial potency.
@en
Structure-activity studies of ...... ity and antimicrobial potency.
@nl
type
label
Structure-activity studies of ...... ity and antimicrobial potency.
@en
Structure-activity studies of ...... ity and antimicrobial potency.
@nl
prefLabel
Structure-activity studies of ...... ity and antimicrobial potency.
@en
Structure-activity studies of ...... ity and antimicrobial potency.
@nl
P2093
P356
P1476
Structure-activity studies of ...... ity and antimicrobial potency.
@en
P2093
Bernard Weisblum
Emilie A Porter
Samuel H Gellman
Tami L Raguse
P304
12774-12785
P356
10.1021/JA0270423
P407
P577
2002-10-01T00:00:00Z