The glucagon-sensitive adenyl cyclase system in plasma membranes of rat liver. V. An obligatory role of guanylnucleotides in glucagon action.
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Glucagon induces disaggregation of polymer-like structures of the alpha subunit of the stimulatory G protein in liver membranesHormone receptor modulates the regulatory component of adenylyl cyclase by reducing its requirement for Mg2+ and enhancing its extent of activation by guanine nucleotidesGuanosine: a Neuromodulator with Therapeutic Potential in Brain DisordersMuscarinic-agonist and guanine nucleotide activation of polyphosphoinositide phosphodiesterase in isolated islet-cell membranesThe discovery of signal transduction by G proteins: a personal account and an overview of the initial findings and contributions that led to our present understanding.Rhodopsin and the others: a historical perspective on structural studies of G protein-coupled receptors.Comparative genomics uncovers novel structural and functional features of the heterotrimeric GTPase signaling system.Cytochemical characterization of the myoepithelial cells in palatine glands.Effects of cholera toxin on adenylate cyclase. Studies with guanylylimidodiphosphate.Potent constitutive cyclic AMP-generating activity of XLαs implicates this imprinted GNAS product in the pathogenesis of McCune-Albright syndrome and fibrous dysplasia of bone.Glucagon receptor of human liver. Studies of its molecular weight and binding properties, and its ability to activate hepatic adenylyl cyclase of non-obese and obese subjects.Signal transduction: evolution of an idea.Mechanism of adenylate cyclase activation by cholera toxin: inhibition of GTP hydrolysis at the regulatory site.Conformational basis for the activation of adenylate cyclase by adenosine.Activation of adenylate cyclase by phosphoramidate and phosphonate analogs of GTP: possible role of covalent enzyme-substrate intermediates in the mechanism of hormonal activation.Action of feedback regulator on adenylate cyclase.Fatty acids as modulators of membrane functions: catecholamine-activated adenylate cyclase of the turkey erythrocyte.A temperature-sensitive change in the energy of activation of hormone-stimulated hepatic adenylyl cyclase.Restoration of glucagon responsiveness in spontaneously transformed rat hepatocytes (RL-PR-C) by fusion with normal progenitor cells and rat liver plasma membranes.Obligatory separation of hormone binding and biological response curves in systems dependent upon secondary mediators of hormone action.Opiates inhibit adenylate cyclase by stimulating GTP hydrolysisOligomerization of G protein-coupled receptors: past, present, and future.Mechanism of adenylate cyclase activation through the beta-adrenergic receptor: catecholamine-induced displacement of bound GDP by GTPPresence of adenylate cyclase activity in Golgi and other fractions from rat liver. II. Cytochemical localization within Golgi and ER membranes.Presence of adenylate cyclase activity in Golgi and other fractions from rat liver. I. Biochemical determination.Pitfalls in the use of lead nitrate for the histochemical demonstration of adenylate cyclase activity.Cholera toxin can catalyze ADP-ribosylation of cytoskeletal proteins.Identification of the guanine binding domain peptide of the GTP-binding site of glucagon.GTP is not required for calmodulin stimulation of bovine brain adenylate cyclasePersistence of increased platelet cyclic AMP induced by prostaglandin E1 after removal of the hormone.Naturally soluble component(s) that confer(s) guanine nucleotide and fluoride sensitivity to adenylate cyclaseHormone-induced guanyl nucleotide binding and activation of adenylate cyclase in the Leydig cell.Cross-talk between angiotensin II and glucagon receptor signaling mediates phosphorylation of mitogen-activated protein kinases ERK 1/2 in rat glomerular mesangial cells.Targeting glucagon receptor signalling in treating metabolic syndrome and renal injury in Type 2 diabetes: theory versus promiseGlucocorticoid receptors and actions in subpopulations of cultured rat bone cells. Mechanism of dexamethasone potentiation of parathyroid hormone-stimulated cyclic AMP production.Molecular properties of muscarinic acetylcholine receptors.GRK2 Constitutively Governs Peripheral Delta Opioid Receptor ActivityCurrent insights and new perspectives on the roles of hyperglucagonemia in non-insulin-dependent type 2 diabetes.Navigating the network: signaling cross-talk in hematopoietic cells.5'-Guanylylimidodiphosphate, a potent activator of adenylate cyclase systems in eukaryotic cells.
P2860
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P2860
The glucagon-sensitive adenyl cyclase system in plasma membranes of rat liver. V. An obligatory role of guanylnucleotides in glucagon action.
description
1971 nî lūn-bûn
@nan
1971年の論文
@ja
1971年学术文章
@wuu
1971年学术文章
@zh
1971年学术文章
@zh-cn
1971年学术文章
@zh-hans
1971年学术文章
@zh-my
1971年学术文章
@zh-sg
1971年學術文章
@yue
1971年學術文章
@zh-hant
name
The glucagon-sensitive adenyl ...... ucleotides in glucagon action.
@en
The glucagon-sensitive adenyl ...... ucleotides in glucagon action.
@nl
type
label
The glucagon-sensitive adenyl ...... ucleotides in glucagon action.
@en
The glucagon-sensitive adenyl ...... ucleotides in glucagon action.
@nl
prefLabel
The glucagon-sensitive adenyl ...... ucleotides in glucagon action.
@en
The glucagon-sensitive adenyl ...... ucleotides in glucagon action.
@nl
P2093
P1476
The glucagon-sensitive adenyl ...... ucleotides in glucagon action.
@en
P2093
P304
P407
P577
1971-03-01T00:00:00Z