Somatostatin receptor subtype 5 regulates insulin secretion and glucose homeostasis.
about
SSTR5 ablation in islet results in alterations in glucose homeostasis in miceAmelioration of hypoglycemia via somatostatin receptor type 2 antagonism in recurrently hypoglycemic diabetic rats.Altered expression of somatostatin receptors in pancreatic islets from NOD mice cultured at different glucose concentrations in vitro and in islets transplanted to diabetic NOD mice in vivo.Neuroendocrine regulation of somatic growth in fishes.SSTR2 is the functionally dominant somatostatin receptor in human pancreatic β- and α-cells.Recent developments in the therapy of acromegaly.Somatostatin receptor expression and biological functions in endocrine pancreatic cells: review based on a doctoral thesis.Reduced brain somatostatin in mood disorders: a common pathophysiological substrate and drug target?Somatostatin and somatostatin receptors: implications for neoplastic growth and cancer biology.Somatostatin receptor biology in neuroendocrine and pituitary tumours: part 2--clinical implicationsRegulation of neuronal nitric-oxide synthase activity by somatostatin analogs following SST5 somatostatin receptor activation.Somatostatin receptor 1-5; expression profiles during rat development.Pasireotide in an insulin-requiring diabetic acromegalic patient without worsening of hyperglycemia.Na+ current properties in islet α- and β-cells reflect cell-specific Scn3a and Scn9a expression.Somatostatin receptors differentially affect spontaneous epileptiform activity in mouse hippocampal slices.The somatostatin analogue SOM230, compared with octreotide, induces differential effects in several metabolic pathways in acromegalic patients.Dopamine D2-like receptors are expressed in pancreatic beta cells and mediate inhibition of insulin secretion.The PDZ/coiled-coil domain containing protein PIST modulates insulin secretion in MIN6 insulinoma cells by interacting with somatostatin receptor subtype 5.Ablation of somatostatin cells leads to impaired pancreatic islet function and neonatal death in rodents.International Union of Basic and Clinical Pharmacology. CV. Somatostatin Receptors: Structure, Function, Ligands, and New Nomenclature
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P2860
Somatostatin receptor subtype 5 regulates insulin secretion and glucose homeostasis.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh
2003年學術文章
@zh-hant
name
Somatostatin receptor subtype 5 regulates insulin secretion and glucose homeostasis.
@en
Somatostatin receptor subtype 5 regulates insulin secretion and glucose homeostasis.
@nl
type
label
Somatostatin receptor subtype 5 regulates insulin secretion and glucose homeostasis.
@en
Somatostatin receptor subtype 5 regulates insulin secretion and glucose homeostasis.
@nl
prefLabel
Somatostatin receptor subtype 5 regulates insulin secretion and glucose homeostasis.
@en
Somatostatin receptor subtype 5 regulates insulin secretion and glucose homeostasis.
@nl
P2093
P921
P356
P1476
Somatostatin receptor subtype 5 regulates insulin secretion and glucose homeostasis.
@en
P2093
Allan D Blake
Bei B Zhang
Deborah Szalkowski
Hilary A Wilkinson
Howard Y Chen
James M Schaeffer
Jill K Fisher
Martin Kohler
Mathias Z Strowski
Myrna E Trumbauer
P304
P356
10.1210/ME.2001-0035
P577
2003-01-01T00:00:00Z