The GAFa domains of rod cGMP-phosphodiesterase 6 determine the selectivity of the enzyme dimerization.
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Mechanism for the allosteric regulation of phosphodiesterase 2A deduced from the X-ray structure of a near full-length constructCrystal structure of the GAF-B domain from human phosphodiesterase 10A complexed with its ligand, cAMPThe Structure of the GAF A Domain from Phosphodiesterase 6C Reveals Determinants of cGMP Binding, a Conserved Binding Surface, and a Large cGMP-dependent Conformational ChangePhosphodiesterase 6C, cGMP-specific cone alpha'.Identification, characterization and subcellular localization of TcPDE1, a novel cAMP-specific phosphodiesterase from Trypanosoma cruzi.Cyclic nucleotide binding GAF domains from phosphodiesterases: structural and mechanistic insightsRod phosphodiesterase-6 PDE6A and PDE6B subunits are enzymatically equivalent.Molecular architecture of photoreceptor phosphodiesterase elucidated by chemical cross-linking and integrative modelingThe upstream conserved regions (UCRs) mediate homo- and hetero-oligomerization of type 4 cyclic nucleotide phosphodiesterases (PDE4s).Dimerization of cAMP phosphodiesterase-4 (PDE4) in living cells requires interfaces located in both the UCR1 and catalytic unit domainsDecreased catalytic activity and altered activation properties of PDE6C mutants associated with autosomal recessive achromatopsiaCyclic nucleotide phosphodiesterases in Drosophila melanogaster.Retinitis pigmentosa: impact of different Pde6a point mutations on the disease phenotype.
P2860
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P2860
The GAFa domains of rod cGMP-phosphodiesterase 6 determine the selectivity of the enzyme dimerization.
description
2003 nî lūn-bûn
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2003年の論文
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2003年学术文章
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2003年学术文章
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name
The GAFa domains of rod cGMP-p ...... ty of the enzyme dimerization.
@en
The GAFa domains of rod cGMP-p ...... ty of the enzyme dimerization.
@nl
type
label
The GAFa domains of rod cGMP-p ...... ty of the enzyme dimerization.
@en
The GAFa domains of rod cGMP-p ...... ty of the enzyme dimerization.
@nl
prefLabel
The GAFa domains of rod cGMP-p ...... ty of the enzyme dimerization.
@en
The GAFa domains of rod cGMP-p ...... ty of the enzyme dimerization.
@nl
P2093
P2860
P356
P1476
The GAFa domains of rod cGMP-p ...... ty of the enzyme dimerization.
@en
P2093
Joseph A Beavo
Khakim G Muradov
Kimberly K Boyd
Nikolai O Artemyev
Sergio E Martinez
P2860
P304
10594-10601
P356
10.1074/JBC.M208456200
P407
P577
2003-01-16T00:00:00Z