Blockade of mesolimbic dopamine transmission dramatically increases sensitivity to the rewarding effects of nicotine in the ventral tegmental area.
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The mechanistic classification of addictive drugsDopamine reward circuitry: two projection systems from the ventral midbrain to the nucleus accumbens-olfactory tubercle complex.Consumption of Substances of Abuse during Pregnancy Increases Consumption in Offspring: Possible Underlying MechanismsCommonalities and Distinctions Among Mechanisms of Addiction to Alcohol and Other DrugsHigh reinforcing efficacy of nicotine in non-human primatesDopamine, learning and motivationAcute administration of nicotine into the higher order auditory Te2 cortex specifically decreases the fear-related charge of remote emotional memoriesSynergistic interaction between nicotine and social rewards in adolescent male ratsThe role of cannabinoid transmission in emotional memory formation: implications for addiction and schizophreniaA role for matrix metalloproteinases in nicotine-induced conditioned place preference and relapse in adolescent female ratsGABAergic and glutamatergic efferents of the mouse ventral tegmental area.The voice of conscience: neural bases of interpersonal guilt and compensation.Adenosine A1 and A2A receptors are not upstream of caffeine's dopamine D2 receptor-dependent aversive effects and dopamine-independent rewarding effectsSelective stimulation of serotonin2c receptors blocks the enhancement of striatal and accumbal dopamine release induced by nicotine administration.Primary reinforcing effects of nicotine are triggered from multiple regions both inside and outside the ventral tegmental area.A concurrent excitation and inhibition of dopaminergic subpopulations in response to nicotineAnimal models to assess the abuse liability of tobacco products: effects of smokeless tobacco extracts on intracranial self-stimulation.Chronic nicotine pretreatment is sufficient to upregulate α4* nicotinic receptors and increase oral nicotine self-administration in mice.Hippocampal cannabinoid transmission modulates dopamine neuron activity: impact on rewarding memory formation and social interaction.Rare nonsynonymous variants in alpha-4 nicotinic acetylcholine receptor gene protect against nicotine dependence.Phasic D1 and tonic D2 dopamine receptor signaling double dissociate the motivational effects of acute nicotine and chronic nicotine withdrawal.Repeated exposure of the posterior ventral tegmental area to nicotine increases the sensitivity of local dopamine neurons to the stimulating effects of ethanolDelivery of nicotine in an extract of a smokeless tobacco product reduces its reinforcement-attenuating and discriminative stimulus effects in ratsNicotine addiction and comorbidity with alcohol abuse and mental illness.Nicotine induces a conditioned place preference in male Japanese quail (Coturnix japonica).Muscle and neuronal nicotinic acetylcholine receptors. Structure, function and pathogenicity.Opiate versus psychostimulant addiction: the differences do matterA psychobiological framework of the substrates that mediate nicotine use during adolescence.Divergent functional effects of sazetidine-a and varenicline during nicotine withdrawal.Localized low-level re-expression of high-affinity mesolimbic nicotinic acetylcholine receptors restores nicotine-induced locomotion but not place conditioning.Effects of nicotine in experimental animals and humans: an update on addictive propertiesAttenuated beta endorphin response to acute stress is associated with smoking relapse.Genetic variation in the dopamine pathway and smoking cessation.Nicotine aversion: Neurobiological mechanisms and relevance to tobacco dependence vulnerability.Nicotinic activation of laterodorsal tegmental neurons: implications for addiction to nicotine.Nicotinic receptors and stages of nicotine dependence.Elevation of dopamine induced by cigarette smoking: novel insights from a [11C]-+-PHNO PET study in humansThe role of alpha6-containing nicotinic acetylcholine receptors in nicotine reward and withdrawal.A systematic review of the A118G (Asn40Asp) variant of OPRM1 in relation to smoking initiation, nicotine dependence and smoking cessation.The neurobiology of opiate motivation.
P2860
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P2860
Blockade of mesolimbic dopamine transmission dramatically increases sensitivity to the rewarding effects of nicotine in the ventral tegmental area.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
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2003年學術文章
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name
Blockade of mesolimbic dopamin ...... in the ventral tegmental area.
@en
Blockade of mesolimbic dopamin ...... in the ventral tegmental area.
@nl
type
label
Blockade of mesolimbic dopamin ...... in the ventral tegmental area.
@en
Blockade of mesolimbic dopamin ...... in the ventral tegmental area.
@nl
prefLabel
Blockade of mesolimbic dopamin ...... in the ventral tegmental area.
@en
Blockade of mesolimbic dopamin ...... in the ventral tegmental area.
@nl
P2860
P356
P1433
P1476
Blockade of mesolimbic dopamin ...... in the ventral tegmental area.
@en
P2093
D van der Kooy
S R Laviolette
P2860
P2888
P304
P356
10.1038/SJ.MP.4001197
P407
P577
2003-01-01T00:00:00Z
P5875
P6179
1050787128