Spironolactone and its main metabolite, canrenoic acid, block human ether-a-go-go-related gene channels.
about
Blockade of HERG potassium currents by fluvoxamine: incomplete attenuation by S6 mutations at F656 or Y652The 5-HT2 antagonist ketanserin is an open channel blocker of human cardiac ether-à-go-go-related gene (hERG) potassium channels.Genomic and nongenomic effects of aldosterone in the rat heart: why is spironolactone cardioprotective?Displacement of cortisol from human heart by acute administration of a mineralocorticoid receptor antagonist.Rapid and MR-Independent IK1 Activation by Aldosterone during Ischemia-Reperfusion.Why are mineralocorticoid receptor antagonists cardioprotective?State-dependent block of HERG potassium channels by R-roscovitine: implications for cancer therapy.The negative inotropic action of canrenone is mediated by L-type calcium current blockade and reduced intracellular calcium transients.Functional consequences of methionine oxidation of hERG potassium channels.Future directions in antiarrhythmic drug therapy for atrial fibrillation.Upstream effect for atrial fibrillation: still a dilemma?Molecular Pathophysiology of Congenital Long QT Syndrome.Association of 14-3-3 proteins to beta1-adrenergic receptors modulates Kv11.1 K+ channel activity in recombinant systems.The calmodulin inhibitor N-(6-aminohexyl)-5-chloro-1-naphthalene sulphonamide directly blocks human ether à-go-go-related gene potassium channels stably expressed in human embryonic kidney 293 cells.Spironolactone and its main metabolite canrenoic acid block hKv1.5, Kv4.3 and Kv7.1 + minK channelsPreferential closed channel blockade of HERG potassium currents by chemically synthesised BeKm-1 scorpion toxin.Aldosterone and testosterone: two steroid hormones structurally related but with opposite electrophysiological properties during myocardial ischemia-reperfusion.
P2860
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P2860
Spironolactone and its main metabolite, canrenoic acid, block human ether-a-go-go-related gene channels.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh-hant
name
Spironolactone and its main me ...... a-go-go-related gene channels.
@en
Spironolactone and its main me ...... a-go-go-related gene channels.
@nl
type
label
Spironolactone and its main me ...... a-go-go-related gene channels.
@en
Spironolactone and its main me ...... a-go-go-related gene channels.
@nl
prefLabel
Spironolactone and its main me ...... a-go-go-related gene channels.
@en
Spironolactone and its main me ...... a-go-go-related gene channels.
@nl
P2093
P50
P1433
P1476
Spironolactone and its main me ...... a-go-go-related gene channels.
@en
P2093
Cristina Arias
Ignacio Moreno
Teresa González
P304
P356
10.1161/01.CIR.0000048189.58449.F7
P407
P577
2003-02-01T00:00:00Z