Differential interactions of lamotrigine and related drugs with transmembrane segment IVS6 of voltage-gated sodium channels.
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Lamotrigine-induced seizures in a child: case report and literature reviewStructural determinants of drugs acting on the Nav1.8 channelMolecular targets for antiepileptic drug developmentIon channels as drug targets in central nervous system disordersProkaryotic NavMs channel as a structural and functional model for eukaryotic sodium channel antagonismThe neurobiology of antiepileptic drugsFast- or slow-inactivated state preference of Na+ channel inhibitors: a simulation and experimental studyAnticonvulsant activity of 2,4(1H)-diarylimidazoles in mice and rats acute seizure models.Novel, broad-spectrum anticonvulsants containing a sulfamide group: pharmacological properties of (S)-N-[(6-chloro-2,3-dihydrobenzo[1,4]dioxin-2-yl)methyl]sulfamide (JNJ-26489112)Analgesic, antiallodynic, and anticonvulsant activity of novel hybrid molecules derived from N-benzyl-2-(2,5-dioxopyrrolidin-1-yl)propanamide and 2-(2,5-dioxopyrrolidin-1-yl)butanamide in animal models of pain and epilepsy.Molecular model of anticonvulsant drug binding to the voltage-gated sodium channel inner pore.Analysis of the action of lidocaine on insect sodium channels.Predictive validity of behavioural animal models for chronic painSynthesis and anticonvulsant activity of new N-phenyl-2-(4-phenylpiperazin-1-yl)acetamide derivatives.Evaluation of anticonvulsant and antinociceptive properties of new N-Mannich bases derived from pyrrolidine-2,5-dione and 3-methylpyrrolidine-2,5-dione.Blocking sodium channels to treat neuropathic pain.Voltage sensor interaction site for selective small molecule inhibitors of voltage-gated sodium channels.Mutant bacterial sodium channels as models for local anesthetic block of eukaryotic proteinsRole of the sixth transmembrane segment of domain IV of the cockroach sodium channel in the action of sodium channel blocker insecticidesModification of distinct ion channels differentially modulates Ca2+ dynamics in primary cultured rat ventricular cardiomyocytes.Voltage-gated sodium channels: biophysics, pharmacology, and related channelopathies.Mechanism of action of sodium channel blocker insecticides (SCBIs) on insect sodium channels.Epigenetic Downregulation of Scn3a Expression by Valproate: a Possible Role in Its Anticonvulsant Activity.Molecular Mechanism of Action and Selectivity of Sodium Channel Blocker Insecticides.Comparative study of lacosamide and classical sodium channel blocking antiepileptic drugs on sodium channel slow inactivation.Exome sequencing of ion channel genes reveals complex profiles confounding personal risk assessment in epilepsy.Antiarrhythmic Action of Flecainide in Polymorphic Ventricular Arrhythmias Caused by a Gain-of-Function Mutation in the Nav 1.5 Sodium Channel.Mechanism of sodium channel block by local anesthetics, antiarrhythmics, and anticonvulsants.Synthesis and anticonvulsant properties of new N-Mannich bases derived from 3,3-diphenyl- and 3-ethyl-3-methyl-pyrrolidine-2,5-diones. Part III.Structural Models of Ligand-Bound Sodium Channels.Short- and long-term complications of in utero exposure to lamotrigine.Voltage-Gated Sodium Channels as Insecticide Targets.
P2860
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P2860
Differential interactions of lamotrigine and related drugs with transmembrane segment IVS6 of voltage-gated sodium channels.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh-hant
name
Differential interactions of l ...... voltage-gated sodium channels.
@en
Differential interactions of l ...... voltage-gated sodium channels.
@nl
type
label
Differential interactions of l ...... voltage-gated sodium channels.
@en
Differential interactions of l ...... voltage-gated sodium channels.
@nl
prefLabel
Differential interactions of l ...... voltage-gated sodium channels.
@en
Differential interactions of l ...... voltage-gated sodium channels.
@nl
P2093
P1433
P1476
Differential interactions of l ...... voltage-gated sodium channels.
@en
P2093
P304
P356
10.1016/S0028-3908(02)00400-8
P577
2003-03-01T00:00:00Z