Opioid activities of fragments of beta-endorphin and of its leucine65-analogue. Comparison of the binding properties of methionine- and leucine-enkephalin.
about
Potent side-chain to side-chain cyclized dermorphin analogues containing a carbonyl bridge.Type and location of fluorescent probes incorporated into the potent mu-opioid peptide [Dmt]DALDA affect potency, receptor selectivity and intrinsic efficacy."Carba"-analogues of fentanyl are opioid receptor agonists.Cyclic enkephalin-deltorphin hybrids containing a carbonyl bridge: structure and opioid activity.'Carba'-carfentanil (trans isomer): a μ opioid receptor (MOR) partial agonist with a distinct binding mode.N-methylated cyclic enkephalin analogues retain high opioid receptor binding affinity.Pharmacological attenuation of chronic alcoholic pancreatitis induced hypersensitivity in rats.Synthesis and biological evaluation of compact, conformationally constrained bifunctional opioid agonist - neurokinin-1 antagonist peptidomimetics.Bifunctional μ/δ opioid peptides: variation of the type and length of the linker connecting the two componentsEffects of changes in the structure of enkephalins and of narcotic analgesic drugs on their interactions with mu- and delta-receptors.Bifunctional Peptide-Based Opioid Agonist-Nociceptin Antagonist Ligands for Dual Treatment of Acute and Neuropathic PainDicarba analogues of the cyclic enkephalin peptides H-Tyr-c[D-Cys-Gly-Phe-D(or L)-Cys]NH(2) retain high opioid activityCyclic opioid peptide agonists and antagonists obtained via ring-closing metathesis.A Cyclic Tetrapeptide ("Cyclodal") and Its Mirror-Image Isomer Are Both High-Affinity μ Opioid Receptor Antagonists.Cyclic enkephalins with a diversely substituted guanidine bridge or a thiourea bridge: synthesis, biological and structural evaluations.[Dmt(1)]DALDA analogues with enhanced μ opioid agonist potency and with a mixed μ/κ opioid activity profileAnalgesic Properties of Opioid/NK1 Multitarget Ligands with Distinct in Vitro Profiles in Naive and Chronic Constriction Injury Mice.Variation of the net charge, lipophilicity, and side chain flexibility in Dmt(1)-DALDA: Effect on Opioid Activity and Biodistribution.Design of novel neurokinin 1 receptor antagonists based on conformationally constrained aromatic amino acids and discovery of a potent chimeric opioid agonist-neurokinin 1 receptor antagonist.Highly potent side-chain to side-chain cyclized enkephalin analogues containing a carbonyl bridge: synthesis, biology and conformation.Relationship between primary structure and activity in exorphins and endogenous opioid peptides.A chimeric opioid peptide with mixed mu agonist/delta antagonist properties.Synthesis and biological evaluation of constrained analogues of the opioid peptide H-Tyr-D-Ala-Phe-Gly-NH2 using the 4-amino-2-benzazepin-3-one scaffold.Synthesis and biological activity of O-glycosylated morphiceptin analogues
P2860
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P2860
Opioid activities of fragments of beta-endorphin and of its leucine65-analogue. Comparison of the binding properties of methionine- and leucine-enkephalin.
description
1979 nî lūn-bûn
@nan
1979年の論文
@ja
1979年学术文章
@wuu
1979年学术文章
@zh
1979年学术文章
@zh-cn
1979年学术文章
@zh-hans
1979年学术文章
@zh-my
1979年学术文章
@zh-sg
1979年學術文章
@yue
1979年學術文章
@zh-hant
name
Opioid activities of fragments ...... onine- and leucine-enkephalin.
@en
Opioid activities of fragments ...... onine- and leucine-enkephalin.
@nl
type
label
Opioid activities of fragments ...... onine- and leucine-enkephalin.
@en
Opioid activities of fragments ...... onine- and leucine-enkephalin.
@nl
prefLabel
Opioid activities of fragments ...... onine- and leucine-enkephalin.
@en
Opioid activities of fragments ...... onine- and leucine-enkephalin.
@nl
P2093
P921
P1476
Opioid activities of fragments ...... onine- and leucine-enkephalin.
@en
P2093
P356
10.1016/0014-2999(79)90334-0
P407
P577
1979-09-01T00:00:00Z