The delta-opioid receptor agonist DADLE at reperfusion protects the heart through activation of pro-survival kinases via EGF receptor transactivation.
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Prospects for Creation of Cardioprotective and Antiarrhythmic Drugs Based on Opioid Receptor Agonistsβ-Adrenergic receptor-mediated transactivation of epidermal growth factor receptor decreases cardiomyocyte apoptosis through differential subcellular activation of ERK1/2 and Akt.Epidermal Growth Factor Receptor Transactivation: Mechanisms, Pathophysiology, and Potential Therapies in the Cardiovascular SystemEvidence for a role of opioids in epoxyeicosatrienoic acid-induced cardioprotection in rat hearts.Alterations of CXCR4 function in μ-opioid receptor-deficient glia.δ-Opioid receptors stimulate GLUT1-mediated glucose uptake through Src- and IGF-1 receptor-dependent activation of PI3-kinase signalling in CHO cellsKappa-opioid receptor activation during reperfusion limits myocardial infarction via ERK1/2 activation in isolated rat hearts.Opioid receptors and cardioprotection - 'opioidergic conditioning' of the heartMorphine and remifentanil-induced cardioprotection: its experimental and clinical outcomes.Role for engagement of β-arrestin2 by the transactivated EGFR in agonist-specific regulation of δ receptor activation of ERK1/2.Inhibition of glycogen synthase kinase 3beta prevents peroxide-induced collapse of mitochondrial membrane potential in rat ventricular myocytes.Myocardial AKT: the omnipresent nexus.Molecular Pharmacology of δ-Opioid Receptors.The epidermal growth factor receptor and its ligands in cardiovascular disease.Redox balance and cardioprotection.Cardioprotective Effects of Intracoronary Morphine in ST-Segment Elevation Myocardial Infarction Patients Undergoing Primary Percutaneous Coronary Intervention: A Prospective, Randomized Trial.Cardiac GPCR-Mediated EGFR Transactivation: Impact and Therapeutic Implications.Delta Opioid Receptors and Cardioprotection.High levels of fatty acids increase contractile function of neonatal rabbit hearts during reperfusion following ischemia.Evidence that cardioprotection by postconditioning involves preservation of myocardial opioid content and selective opioid receptor activation.Essential role of EGFR in cardioprotection and signaling responses to A1 adenosine receptors and ischemic preconditioning.Acute and chronic adrenergic stimulation of submandibular salivary glands. Effects on the endocrine function of epidermal growth factor in mice.ErbB receptors protect the perfused heart against injury induced by epinephrine combined with low-flow ischemia.[D-Ala2,D-Leu5]-enkephalin (DADLE) and morphine-induced postconditioning by inhibition of mitochondrial permeability transition pore, in human myocardium.Cardiac ErbB-1/ErbB-2 mutant expression in young adult mice leads to cardiac dysfunction.Acetylcholine inhibits tumor necrosis factor α activated endoplasmic reticulum apoptotic pathway via EGFR-PI3K signaling in cardiomyocytes.Chitosan nanoparticles are efficient carriers for delivering biodegradable drugs to neuronal cells.Apelin-induced cardioprotection against ischaemia/reperfusion injury: roles of epidermal growth factor and Src.Myocardial Opioid Receptors in Conditioning and Cytoprotection.
P2860
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P2860
The delta-opioid receptor agonist DADLE at reperfusion protects the heart through activation of pro-survival kinases via EGF receptor transactivation.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh
2007年學術文章
@zh-hant
name
The delta-opioid receptor agon ...... EGF receptor transactivation.
@en
The delta-opioid receptor agon ...... EGF receptor transactivation.
@nl
type
label
The delta-opioid receptor agon ...... EGF receptor transactivation.
@en
The delta-opioid receptor agon ...... EGF receptor transactivation.
@nl
prefLabel
The delta-opioid receptor agon ...... EGF receptor transactivation.
@en
The delta-opioid receptor agon ...... EGF receptor transactivation.
@nl
P2093
P2860
P1476
The delta-opioid receptor agon ...... a EGF receptor transactivation
@en
P2093
Atsushi Kuno
Karina Förster
Natalia Solenkova
Stephan B Felix
P2860
P304
P356
10.1152/AJPHEART.00418.2007
P50
P577
2007-06-01T00:00:00Z