Identification of a novel Bcl-xL phosphorylation site regulating the sensitivity of taxol- or 2-methoxyestradiol-induced apoptosis.
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Cyclin-dependent kinase 1-mediated Bcl-xL/Bcl-2 phosphorylation acts as a functional link coupling mitotic arrest and apoptosisBcl-xL phosphorylation at Ser49 by polo kinase 3 during cell cycle progression and checkpointsMitogen Activated Protein kinase signal transduction pathways in the prostateInhibitors of phosphatidylinositol 3'-kinases promote mitotic cell death in HeLa cellsThe flexible loop of Bcl-2 is required for molecular interaction with immunosuppressant FK-506 binding protein 38 (FKBP38)Combination of Quercetin and 2-Methoxyestradiol Enhances Inhibition of Human Prostate Cancer LNCaP and PC-3 Cells Xenograft Tumor Growthc-Jun N-terminal kinase mediates mouse liver injury through a novel Sab (SH3BP5)-dependent pathway leading to inactivation of intramitochondrial Src.Expression of human Bcl-xL (Ser49) and (Ser62) mutants in Caenorhabditis elegans causes germline defects and aneuploidy.Salicylate •Phenanthroline copper (II) complex induces apoptosis in triple-negative breast cancer cells.Ceramide promotes apoptosis in chronic myelogenous leukemia-derived K562 cells by a mechanism involving caspase-8 and JNKMst1 promotes cardiac myocyte apoptosis through phosphorylation and inhibition of Bcl-xLNeuroprotectin D1 induces dephosphorylation of Bcl-xL in a PP2A-dependent manner during oxidative stress and promotes retinal pigment epithelial cell survivalResveratrol attenuates the anticancer efficacy of paclitaxel in human breast cancer cells in vitro and in vivo.Antitumor activity and downregulation of pro-angiogenic molecules in human prostate cancer cells by a novel thiazolidione compoundRole of Bcl-xL/Beclin-1 in synergistic apoptotic effects of secretory TRAIL-armed adenovirus in combination with mitomycin C and hyperthermia on colon cancer cells.Sorafenib inhibits ERK1/2 and MCL-1(L) phosphorylation levels resulting in caspase-independent cell death in malignant pleural mesothelioma.Inhibition of Mdm2 sensitizes human retinal pigment epithelial cells to apoptosis.tLivin displays flexibility by promoting alternative cell death mechanismsTyrosine-phosphorylated caveolin-1 (Tyr-14) increases sensitivity to paclitaxel by inhibiting BCL2 and BCLxL proteins via c-Jun N-terminal kinase (JNK).Dynamic Bcl-xL (S49) and (S62) Phosphorylation/Dephosphorylation during Mitosis Prevents Chromosome Instability and Aneuploidy in Normal Human Diploid FibroblastsBcl-xL controls a switch between cell death modes during mitotic arrestMLN4924 Synergistically Enhances Cisplatin-induced Cytotoxicity via JNK and Bcl-xL Pathways in Human Urothelial CarcinomaHypoxia Promotes Synergy between Mitomycin C and Bortezomib through a Coordinated Process of Bcl-xL Phosphorylation and Mitochondrial Translocation of p53.Cdk2 phosphorylation of Bcl-xL after stress converts it to a pro-apoptotic protein mimicking Bax/Bak.Hyaluronan and hyaluronidase in genitourinary tumors.Efficacy of focal adhesion kinase inhibition in non-small cell lung cancer with oncogenically activated MAPK pathways.Progressive apoptosis resistance prior to senescence and control by the anti-apoptotic protein BCL-xL.Hyalurondiase: both a tumor promoter and suppressor.Critical role of anti-apoptotic Bcl-2 protein phosphorylation in mitotic death.How to unleash mitochondrial apoptotic blockades to kill cancers?Role of Bcl-xL/Beclin-1 in interplay between apoptosis and autophagy in oxaliplatin and bortezomib-induced cell death.Inhibition of Oncogenic Transcription Factor REL by the Natural Product Derivative Calafianin Monomer 101 Induces Proliferation Arrest and Apoptosis in Human B-Lymphoma Cell Lines.Therapeutic inhibition of BCL-2 and related family members.BCL2 and BCLxL are key determinants of resistance to antitubulin chemotherapeutics in melanoma cells.The role of Bcl-xL in synergistic induction of apoptosis by mapatumumab and oxaliplatin in combination with hyperthermia on human colon cancer.Phospho-Bcl-xL(Ser62) influences spindle assembly and chromosome segregation during mitosisProtoapigenone, a natural derivative of apigenin, induces mitogen-activated protein kinase-dependent apoptosis in human breast cancer cells associated with induction of oxidative stress and inhibition of glutathione S-transferase π.Identification of the major phosphorylation site in Bcl-xL induced by microtubule inhibitors and analysis of its functional significance.Polo-like kinase 1 phosphorylates and regulates Bcl-x(L) during pironetin-induced apoptosis.The nucleoside analog sangivamycin induces apoptotic cell death in breast carcinoma MCF7/adriamycin-resistant cells via protein kinase Cdelta and JNK activation.
P2860
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P2860
Identification of a novel Bcl-xL phosphorylation site regulating the sensitivity of taxol- or 2-methoxyestradiol-induced apoptosis.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh-hant
name
Identification of a novel Bcl- ...... xyestradiol-induced apoptosis.
@en
Identification of a novel Bcl- ...... xyestradiol-induced apoptosis.
@nl
type
label
Identification of a novel Bcl- ...... xyestradiol-induced apoptosis.
@en
Identification of a novel Bcl- ...... xyestradiol-induced apoptosis.
@nl
prefLabel
Identification of a novel Bcl- ...... xyestradiol-induced apoptosis.
@en
Identification of a novel Bcl- ...... xyestradiol-induced apoptosis.
@nl
P2860
P1433
P1476
Identification of a novel Bcl- ...... xyestradiol-induced apoptosis.
@en
P2093
Aruna Basu
Subrata Haldar
P2860
P356
10.1016/S0014-5793(03)00131-5
P407
P577
2003-03-01T00:00:00Z