Ceramide-induced neuronal apoptosis is associated with dephosphorylation of Akt, BAD, FKHR, GSK-3beta, and induction of the mitochondrial-dependent intrinsic caspase pathway.
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Sphingolipids as cell fate regulators in lung development and diseaseCeramides in Alzheimer's Disease: Key Mediators of Neuronal Apoptosis Induced by Oxidative Stress and Aβ AccumulationThe PI3K-NF-kappaB signal transduction pathway is involved in mediating the anti-inflammatory effect of IB-MECA in adjuvant-induced arthritisMitochondrial lipids in neurodegenerationMitochondrial injury after mechanical stretch of cortical neurons in vitro: biomarkers of apoptosis and selective peroxidation of anionic phospholipidsThe anti-inflammatory effect of A3 adenosine receptor agonists: a novel targeted therapy for rheumatoid arthritis.The modular systems biology approach to investigate the control of apoptosis in Alzheimer's disease neurodegeneration.Glycogen synthase kinase 3 alpha and 3 beta have distinct functions during cardiogenesis of zebrafish embryo.Downregulation of miR-23a and miR-27a following experimental traumatic brain injury induces neuronal cell death through activation of proapoptotic Bcl-2 proteins.Roles for dysfunctional sphingolipid metabolism in Alzheimer's disease neuropathogenesis.Metabolic derangements mediate cognitive impairment and Alzheimer's disease: role of peripheral insulin-resistance diseasesPrenatal alcohol exposure triggers ceramide-induced apoptosis in neural crest-derived tissues concurrent with defective cranial development.The role of the Hsp90/Akt pathway in myocardial calpain-induced caspase-3 activation and apoptosis during sepsis.Cancer treatment strategies targeting sphingolipid metabolism.Ceramides as modulators of cellular and whole-body metabolismThe prognostic impact of Akt isoforms, PI3K and PTEN related to female steroid hormone receptors in soft tissue sarcomas.Role of the Insulin-Like Growth Factor Type 1 Receptor in the Pathogenesis of Diabetic Encephalopathy.Triangulated mal-signaling in Alzheimer's disease: roles of neurotoxic ceramides, ER stress, and insulin resistance reviewedSerum ceramides increase the risk of Alzheimer disease: the Women's Health and Aging Study II.SGK-1 protects kidney cells against apoptosis induced by ceramide and TNF-αIndependent transcriptional reprogramming and apoptosis induction by cisplatin.Acetaldehyde Induces Cytotoxicity of SH-SY5Y Cells via Inhibition of Akt Activation and Induction of Oxidative Stress.Ceramide signaling in cancer and stem cells.Ablation of dihydroceramide desaturase 1, a therapeutic target for the treatment of metabolic diseases, simultaneously stimulates anabolic and catabolic signalingMolecular physiology of preconditioning-induced brain tolerance to ischemia.Smart drugs for smarter stem cells: making SENSe (sphingolipid-enhanced neural stem cells) of ceramide.Ceramide and neurodegeneration: susceptibility of neurons and oligodendrocytes to cell damage and death.Converging roles for sphingolipids and cell stress in the progression of neuro-AIDSmiR-711 upregulation induces neuronal cell death after traumatic brain injury.Mitochondria in neuroplasticity and neurological disorders.Bim regulation may determine hippocampal vulnerability after injurious seizures and in temporal lobe epilepsy.Ceramide and mitochondria in ischemia/reperfusion.A phthalide derivative isolated from endophytic fungi Pestalotiopsis photiniae induces G1 cell cycle arrest and apoptosis in human HeLa cells.Ceramide and mitochondria in ischemic brain injury.Vitamin K, an emerging nutrient in brain function.Sphingolipids and mitochondrial apoptosis.Ceramide in the molecular mechanisms of neuronal cell death. The role of sphingosine-1-phosphate.Pachastrissamine from Pachastrissa sp. inhibits melanoma cell growth by dual inhibition of Cdk2 and ERK-mediated FOXO3 downregulation.Bcl-2 rescues ceramide- and etoposide-induced mitochondrial apoptosis through blockage of caspase-2 activation.Chandipura virus perturbs cholesterol homeostasis leading to neuronal apoptosis.
P2860
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P2860
Ceramide-induced neuronal apoptosis is associated with dephosphorylation of Akt, BAD, FKHR, GSK-3beta, and induction of the mitochondrial-dependent intrinsic caspase pathway.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh-hant
name
Ceramide-induced neuronal apop ...... ent intrinsic caspase pathway.
@en
Ceramide-induced neuronal apop ...... ent intrinsic caspase pathway.
@nl
type
label
Ceramide-induced neuronal apop ...... ent intrinsic caspase pathway.
@en
Ceramide-induced neuronal apop ...... ent intrinsic caspase pathway.
@nl
prefLabel
Ceramide-induced neuronal apop ...... ent intrinsic caspase pathway.
@en
Ceramide-induced neuronal apop ...... ent intrinsic caspase pathway.
@nl
P2093
P1476
Ceramide-induced neuronal apop ...... ent intrinsic caspase pathway.
@en
P2093
Alan I Faden
Bogdan A Stoica
Paul M Lea
Vilen A Movsesyan
P304
P356
10.1016/S1044-7431(02)00028-3
P577
2003-03-01T00:00:00Z