Polo-like kinase 1 (PLK1) is overexpressed in primary colorectal cancers. - Wikidata - wikimedia - TriplyDB

Polo-like kinase 1 (PLK1) is overexpressed in primary colorectal cancers.

Polo-like kinase 1 (PLK1) is overexpressed in primary colorectal cancers.

http://www.wikidata.org/entity/Q44412178

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Time- and dose-dependent effects of curcumin on gene expression in human colon cancer cells Polo-like kinase 1, on the rise from cell cycle regulation to prostate cancer development Cross Talk between Wnt/β-Catenin and CIP2A/Plk1 Signaling in Prostate Cancer: Promising Therapeutic Implications PLK1, A Potential Target for Cancer Therapy Polo-like kinase and its inhibitors: Ready for the match to start?A series of beta-carboline derivatives inhibit the kinase activity of PLKs Modulation of key regulators of mitosis linked to chromosomal instability is an early event in ochratoxin A carcinogenicity Cancer biomarker discovery: the entropic hallmark.Protein tyrosine phosphatase Shp2 (Ptpn11) plays an important role in maintenance of chromosome stability PLK1 blockade enhances therapeutic effects of radiation by inducing cell cycle arrest at the mitotic phase.A randomised phase II trial of the Polo-like kinase inhibitor BI 2536 in chemo-naïve patients with unresectable exocrine adenocarcinoma of the pancreas - a study within the Central European Society Anticancer Drug Research (CESAR) collaborative netw An open-label, single-arm, phase 2 trial of the Polo-like kinase inhibitor volasertib (BI 6727) in patients with locally advanced or metastatic urothelial cancer A phase I study of two dosing schedules of volasertib (BI 6727), an intravenous polo-like kinase inhibitor, in patients with advanced solid malignancies.Phase I trial of volasertib, a Polo-like kinase inhibitor, plus platinum agents in solid tumors: safety, pharmacokinetics and activity A phase I study of volasertib combined with afatinib, in advanced solid tumors.Phase I trial of volasertib, a Polo-like kinase inhibitor, in Japanese patients with advanced solid tumors.Expression of the microtubule-associated protein MAP9/ASAP and its partners AURKA and PLK1 in colorectal and breast cancers.The RNA helicase/transcriptional co-regulator, p68 (DDX5), stimulates expression of oncogenic protein kinase, Polo-like kinase-1 (PLK1), and is associated with elevated PLK1 levels in human breast cancers Depsides isolated from the Sri Lankan lichen Parmotrema sp. exhibit selective Plk1 inhibitory activity.High expression of polo-like kinase 1 is associated with early development of hepatocellular carcinoma.Towards Prognostic Profiling of Non-Small Cell Lung Cancer: New Perspectives on the Relevance of Polo-Like Kinase 1 Expression, the TP53 Mutation Status and Hypoxia PLK1 interacts and phosphorylates Axin that is essential for proper centrosome formation.Animal models of colitis-associated carcinogenesis.The chromosomal instability pathway in colon cancer Identification of novel compounds that enhance colon cancer cell sensitivity to inflammatory apoptotic ligands.Kinome-wide functional screen identifies role of PLK1 in hormone-independent, ER-positive breast cancer.Autoinhibition and relief mechanism for Polo-like kinase 4.Polo-like kinase 1 regulates cell proliferation and is targeted by miR-593* in esophageal cancer.Upregulated Polo-Like Kinase 1 Expression Correlates with Inferior Survival Outcomes in Rectal Cancer Phase i study of the Plk1 inhibitor BI 2536 administered intravenously on three consecutive days in advanced solid tumours.Oncogenic regulators and substrates of the anaphase promoting complex/cyclosome are frequently overexpressed in malignant tumors.Immunohistochemical detection of Polo-like kinase-1 (PLK1) in primary breast cancer is associated with TP53 mutation and poor clinical outcom JNK-associated Leucine Zipper Protein Functions as a Docking Platform for Polo-like Kinase 1 and Regulation of the Associating Transcription Factor Forkhead Box Protein K1.Polo-like kinase 1 is overexpressed in colorectal cancer and participates in the migration and invasion of colorectal cancer cells.Polo-like kinase 1 overexpression is an early event in the progression of papillary carcinoma.ARHGAP10, downregulated in ovarian cancer, suppresses tumorigenicity of ovarian cancer cells.Discovery and scoring of protein interaction subnetworks discriminative of late stage human colon cancer Overexpression of polo-like kinase1 predicts a poor prognosis in hepatocellular carcinoma patients.Important molecular genetic markers of colorectal cancer.Targeting of polo-like kinases and their cross talk with Aurora kinases--possible therapeutic strategies in human acute myeloid leukemia?

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Polo-like kinase 1 (PLK1) is overexpressed in primary colorectal cancers.

http://www.wikidata.org/entity/Q44412178

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2003年學術文章

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2003年學術文章

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name

Polo-like kinase 1 (PLK1) is overexpressed in primary colorectal cancers.

@en

type

label

Polo-like kinase 1 (PLK1) is overexpressed in primary colorectal cancers.

@en

prefLabel

Polo-like kinase 1 (PLK1) is overexpressed in primary colorectal cancers.

@en

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Polo-like kinase 1 (PLK1) is overexpressed in primary colorectal cancers.

@en

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Bun Sano

http://www.w3.org/2001/XMLSchema#string

Hiroki Kato

http://www.w3.org/2001/XMLSchema#string

Katsuyuki Kunieda

http://www.w3.org/2001/XMLSchema#string

Masashi Kimura

http://www.w3.org/2001/XMLSchema#string

Shigetoyo Saji

http://www.w3.org/2001/XMLSchema#string

Takao Takahashi

http://www.w3.org/2001/XMLSchema#string

Takayasu Nagata

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Yasuyuki Sugiyama

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Yukio Okano

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P2860

Cell cycle regulation of the activity and subcellular localization of Plk1, a human protein kinase implicated in mitotic spindle function

The spread of rectal cancer and its effect on prognosis

A genetic model for colorectal tumorigenesis

Malignant transformation of mammalian cells initiated by constitutive expression of the polo-like kinase

Mitotic kinases as regulators of cell division and its checkpoints

Mutations in aurora prevent centrosome separation leading to the formation of monopolar spindles

Polo-like kinases: positive regulators of cell division from start to finish.

Centrosome hypertrophy in human breast tumors: implications for genomic stability and cell polarity.

Expression of polo-like kinase in ovarian cancer is associated with histological grade and clinical stage.

Polo-like kinase (PLK) expression in endometrial carcinoma.

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