Calpains mediate p53 activation and neuronal death evoked by DNA damage.
about
CAPN 7 promotes the migration and invasion of human endometrial stromal cell by regulating matrix metalloproteinase 2 activityThe C terminus of p53 family proteins is a cell fate determinantm-Calpain is required for preimplantation embryonic development in mice.Oxidative stress, DNA damage, and the telomeric complex as therapeutic targets in acute neurodegenerationPhosphorylation of ATM by Cdk5 mediates DNA damage signalling and regulates neuronal deathDisruption of the axon initial segment cytoskeleton is a new mechanism for neuronal injury.Conditional disruption of calpain in the CNS alters dendrite morphology, impairs LTP, and promotes neuronal survival following injury.Endocannabinoids prevent β-amyloid-mediated lysosomal destabilization in cultured neurons.Neuroprotective strategies against calpain-mediated neurodegeneration.Cell signaling underlying epileptic behavior.Caspase-dependent and -independent neuronal death: two distinct pathways to neuronal injury.Gene activation and protein expression following ischaemic stroke: strategies towards neuroprotection.Proteolytic mechanisms in necrotic cell death and neurodegeneration.Gonadal steroids block the calpain-1-dependent intrinsic pathway of apoptosis in an experimental rat stroke model.Involvement of calpain activation in neurodegenerative processes.Non-conventional apoptotic response to ionising radiation mediated by N-methyl D-aspartate receptors in immature neuronal cells.Olesoxime protects embryonic cortical neurons from camptothecin intoxication by a mechanism distinct from BDNF.Perturbation of transcription factor Nur77 expression mediated by myocyte enhancer factor 2D (MEF2D) regulates dopaminergic neuron loss in response to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).Calpain-mediated signaling mechanisms in neuronal injury and neurodegenerationThe calpain system and cancer.Effects of copper overload in P19 neurons: impairment of glutathione redox homeostasis and crosstalk between caspase and calpain protease systems in ROS-induced apoptosis.Reduced hippocampal damage and epileptic seizures after status epilepticus in mice lacking proapoptotic Puma.Identification of dihydropyrimidinase-related protein 4 as a novel target of the p53 tumor suppressor in the apoptotic response to DNA damage.Calcium-dependent regulation of NEMO nuclear export in response to genotoxic stimuli.Inhibition of the cdk5/MEF2 pathway is involved in the antiapoptotic properties of calpain inhibitors in cerebellar neurons.The nuclear localization of SET mediated by impalpha3/impbeta attenuates its cytosolic toxicity in neurons.Inhibition of nucleolar transcription as a trigger for neuronal apoptosis.Calpain-dependent cleavage of N-cadherin is involved in the progression of post-myocardial infarction remodeling.PINK1-mediated phosphorylation of LETM1 regulates mitochondrial calcium transport and protects neurons against mitochondrial stress.c-Jun N-terminal kinase 3 deficiency protects neurons from axotomy-induced death in vivo through mechanisms independent of c-Jun phosphorylation.Liver X receptor activation enhances blood-brain barrier integrity in the ischemic brain and increases the abundance of ATP-binding cassette transporters ABCB1 and ABCC1 on brain capillary cells.
P2860
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P2860
Calpains mediate p53 activation and neuronal death evoked by DNA damage.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh-hant
name
Calpains mediate p53 activation and neuronal death evoked by DNA damage.
@en
Calpains mediate p53 activation and neuronal death evoked by DNA damage.
@nl
type
label
Calpains mediate p53 activation and neuronal death evoked by DNA damage.
@en
Calpains mediate p53 activation and neuronal death evoked by DNA damage.
@nl
prefLabel
Calpains mediate p53 activation and neuronal death evoked by DNA damage.
@en
Calpains mediate p53 activation and neuronal death evoked by DNA damage.
@nl
P2093
P2860
P356
P1476
Calpains mediate p53 activation and neuronal death evoked by DNA damage
@en
P2093
Edon Melloni
Elizabeth Keramaris
John S Elce
Mary Sedarous
Michael O'Hare
Peter A Greer
Ruth S Slack
P2860
P304
26031-26038
P356
10.1074/JBC.M302833200
P407
P50
P577
2003-04-29T00:00:00Z