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Redefining the major peanut allergensSignaling pathways that lead to the silencing of the interleukin-4-producing potential in Th1 cells.Analysis of the effector activity of Ara h 2 and Ara h 6 by selective depletion from a crude peanut extractThe 2S albumin allergens of Arachis hypogaea, Ara h 2 and Ara h 6, are the major elicitors of anaphylaxis and can effectively desensitize peanut-allergic mice.ERK1 is important for Th2 differentiation and development of experimental asthma.Daxx upregulation within the cytoplasm of reovirus-infected cells is mediated by interferon and contributes to apoptosis.IFN-γ suppresses permissive chromatin remodeling in the regulatory region of the Il4 gene.Ara h 2 and Ara h 6 have similar allergenic activity and are substantially redundantAntagonistic regulation by the transcription factors C/EBPα and MITF specifies basophil and mast cell fates.Expression of recombinant Ara h 6 in Pichia pastoris but not in Escherichia coli preserves allergic effector function and allows assessment of specific mutations.A continuous T-bet expression is required to silence the interleukin-4-producing potential in T helper type 1 cells.
P50
Q27023714-6745318B-4B85-4CA8-9530-D8691B9D5A85Q34208020-09923D30-7B57-481B-BEC0-9CDC44056E10Q35206837-FDF2F6E3-4486-49A6-BDD3-A0CB0DC90703Q35724447-91431151-9672-4D38-96DB-24C68E592ECBQ35913003-009041E6-14D7-406D-84B9-BE01B18DC272Q36667990-25E09424-146D-4EE3-99BD-15FEE0EE7463Q36736178-F7B03651-90E1-477B-A12C-42BBDEF04F90Q36838762-1C0FCB3F-D1C8-42CD-98D1-CB6ECC5A94ECQ37127767-34A7F6D6-2EA0-40AE-84F8-6EBDA1BE8027Q39329667-57953F8E-F3E3-4F40-B13C-886AC0991570Q44433415-4993AFE6-3E10-4A06-A8B3-7E8691D57D66
P50
description
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Yonghua Zhuang
@ast
Yonghua Zhuang
@en
Yonghua Zhuang
@es
Yonghua Zhuang
@nl
Yonghua Zhuang
@sl
type
label
Yonghua Zhuang
@ast
Yonghua Zhuang
@en
Yonghua Zhuang
@es
Yonghua Zhuang
@nl
Yonghua Zhuang
@sl
prefLabel
Yonghua Zhuang
@ast
Yonghua Zhuang
@en
Yonghua Zhuang
@es
Yonghua Zhuang
@nl
Yonghua Zhuang
@sl
P1053
A-2946-2013
P106
P1153
35106378200
P31
P3829
P496
0000-0002-1822-2395