The combination of 4-1BBL and CD40L strongly enhances the capacity of dendritic cells to stimulate HIV-specific T cell responses.
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4-1BB Agonists: Multi-Potent Potentiators of Tumor ImmunityManipulation of costimulatory molecules by intracellular pathogens: veni, vidi, vici!!Soluble multi-trimeric TNF superfamily ligand adjuvants enhance immune responses to a HIV-1 Gag DNA vaccine.Transgenic 4-1BBL-engineered vaccine stimulates potent Gag-specific therapeutic and long-term immunity via increased priming of CD44(+)CD62L(high) IL-7R(+) CTLs with up- and downregulation of anti- and pro-apoptosis genes.Expansion of polyfunctional HIV-specific T cells upon stimulation with mRNA electroporated dendritic cells in the presence of immunomodulatory drugsCo-expression of CD40L with CD70 or OX40L increases B-cell viability and antitumor efficacy.Enhancing immunogenicity and cross-reactivity of HIV-1 antigens by in vivo targeting to dendritic cells.Modulation of tumor immunity by soluble and membrane-bound molecules at the immunological synapse.mRNA-based dendritic cell vaccines.The future of immune checkpoint cancer therapy after PD-1 and CTLA-4.Lipoplexes carrying mRNA encoding Gag protein modulate dendritic cells to stimulate HIV-specific immune responses.Adjuvant-Enhanced mRNA Vaccines.mRNA vaccines - a new era in vaccinology.Strategies to Genetically Modulate Dendritic Cells to Potentiate Anti-Tumor Responses in Hematologic Malignancies.
P2860
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P2860
The combination of 4-1BBL and CD40L strongly enhances the capacity of dendritic cells to stimulate HIV-specific T cell responses.
description
2011 nî lūn-bûn
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name
The combination of 4-1BBL and ...... HIV-specific T cell responses.
@en
The combination of 4-1BBL and ...... HIV-specific T cell responses.
@nl
type
label
The combination of 4-1BBL and ...... HIV-specific T cell responses.
@en
The combination of 4-1BBL and ...... HIV-specific T cell responses.
@nl
prefLabel
The combination of 4-1BBL and ...... HIV-specific T cell responses.
@en
The combination of 4-1BBL and ...... HIV-specific T cell responses.
@nl
P2093
P2860
P356
P1476
The combination of 4-1BBL and ...... HIV-specific T cell responses.
@en
P2093
Carlo Heirman
Christophe Empsen
Joeri L Aerts
Jurgen Corthals
Kris Thielemans
Patrick Lacor
Sabine D Allard
P2860
P304
P356
10.1189/JLB.0810466
P577
2011-03-22T00:00:00Z