Properdin can initiate complement activation by binding specific target surfaces and providing a platform for de novo convertase assembly.
about
Alternative Pathway Dysregulation and the Conundrum of Complement Activation by IgG4 Immune Complexes in Membranous NephropathySystemic Lupus Erythematosus and Deficiencies of Early Components of the Complement Classical PathwayComplement activation in the context of stem cells and tissue repairMolecular mechanisms of inflammation and tissue injury after major trauma--is complement the "bad guy"?Do antimicrobial peptides and complement collaborate in the intestinal mucosa?Structural basis for inhibition of complement C5 by the SSL7 protein from Staphylococcus aureusStructural basis for sialic acid-mediated self-recognition by complement factor HProperdin: a tightly regulated critical inflammatory modulatorVariability and action mechanism of a family of anticomplement proteins in Ixodes ricinusFunctional analysis of Ficolin-3 mediated complement activationInfections of People with Complement Deficiencies and Patients Who Have Undergone SplenectomyComplement: a key system for immune surveillance and homeostasisCombination of factor H mutation and properdin deficiency causes severe C3 glomerulonephritisStructural basis for the stabilization of the complement alternative pathway C3 convertase by properdin.Complement-mediated injury and protection of endothelium: lessons from atypical haemolytic uraemic syndromeMolecules Great and Small: The Complement System.A novel antibody against human properdin inhibits the alternative complement system and specifically detects properdin from blood samples.Complement evasion by human pathogens.Fluid phase recognition molecules in neutrophil-dependent immune responses.Review: Complement and its regulatory proteins in kidney diseases.Properdin has an ascendancy over factor H regulation in complement-mediated renal tubular damage.Targeted inhibition of the complement alternative pathway with complement receptor 2 and factor H attenuates collagen antibody-induced arthritis in miceA diverse host thrombospondin-type-1 repeat protein repertoire promotes symbiont colonization during establishment of cnidarian-dinoflagellate symbiosis.Identification of tubular heparan sulfate as a docking platform for the alternative complement component properdin in proteinuric renal diseaseComplement activation by CpG in a human whole blood loop system: mechanisms and immunomodulatory effects.Activation of complement factor B contributes to murine and human myocardial ischemia/reperfusion injury.Complement control protein factor H: the good, the bad, and the inadequate.Role and mechanism of action of complement in regulating T cell immunity.An evaluation of the role of properdin in alternative pathway activation on Neisseria meningitidis and Neisseria gonorrhoeae.Genetic and therapeutic targeting of properdin in mice prevents complement-mediated tissue injury.Native polymeric forms of properdin selectively bind to targets and promote activation of the alternative pathway of complementComplement-targeted therapeuticsProperdin homeostasis requires turnover of the alternative complement pathwayMeningococcal disease and the complement system.Complementing the inflammasome.Role of complement in host-microbe homeostasis of the periodontium.The alternative pathway of complement activation may be involved in the renal damage of human anti-glomerular basement membrane disease.Islet amyloid polypeptide triggers limited complement activation and binds complement inhibitor C4b-binding protein, which enhances fibril formation.Quantitative Modeling of the Alternative Pathway of the Complement SystemRegulation of complement by cartilage oligomeric matrix protein allows for a novel molecular diagnostic principle in rheumatoid arthritis
P2860
Q26747416-32DB5154-54B5-443D-A878-C42434CB879AQ26768534-1AB6723F-931E-460C-A56E-D689BBB22B65Q26782203-B72D44C7-7C3D-4049-84D2-4C087AEE9517Q26825724-90DD3669-E63E-4E2F-A57C-5A0ADE135798Q26865903-6E716AC9-C341-4BDE-82D0-964D05E50395Q27659556-B46C388E-2608-4954-95DD-84DAA8C8B376Q27696183-583891EC-6BDE-40E6-8B52-A82F8D243C71Q28069187-2ABE5F1B-7D47-4E3C-B77C-FADA3B50A604Q28471851-C0C75AD9-E9A5-4D2A-B688-5670BEAE1291Q28476068-F19A4E85-9612-42E1-972A-5B6EEB42B351Q28972389-B12D89A7-9323-44B4-BD54-2422FBD6B303Q29615484-0BD2F2D3-9C67-4BFD-9C0D-69F7B213684EQ30415634-CD9BB1EA-AFD2-4B81-80C4-3FBE51C91DEEQ30543168-71061B25-2E35-490A-A27D-CCCACBA6F95BQ33396792-56BA9F0E-F72E-4811-B522-2A2D077BEDADQ33419651-15073C02-8915-46E2-9283-9BD0B58BEF38Q33568131-8A814345-3C07-4000-9234-FE46D2BC313DQ33623972-13F45C45-2120-421F-97E2-94AA3B6D8E26Q33626308-17BB4ACB-1DF0-464F-A55A-F8EA00710156Q33647738-041D1281-5EBA-4F9A-941D-ADFB28397C91Q33680856-EE7D95A0-637B-4249-8441-496868E0A28BQ33687307-F45ACC07-3465-45ED-9A7B-8B9F6A047A93Q33732352-6D4B2681-2ADC-4A75-A6FA-2839BD7454D8Q33764140-510F4607-9CBE-4991-B6B7-C7FBD6B60883Q33801802-A487A487-1246-495B-9DCE-798E5E27AA56Q33852943-12F096BB-47CA-430D-A7AE-462A695DD4B9Q34067107-E51875B2-5AD6-439E-9E89-759BFF2D0F8AQ34072846-A86E670C-66F9-491A-B7DC-D4A4872A5581Q34105747-30FE75BE-D264-4C96-B784-C6396C9DAA97Q34162118-B5773752-4A64-4417-B0C7-9F94D0104EB6Q34172424-A47B67EC-FFAB-4721-9248-A2D3E28E6E96Q34255011-00C26EB4-DBF5-4905-B5B1-FBDF4C8D3C55Q34320277-0FB4469B-2665-4B6C-ABAA-8FAEE0776C46Q34376170-960840E7-097A-45A2-94AA-08134D93CFA2Q34501875-92127C1B-A45B-4496-B3ED-0BF47D963B0EQ34727808-C1B54E1B-65DE-4A65-884E-A8D62657066EQ35127927-195807B3-A950-4C25-AA42-3058B40A96A1Q35879624-8BE76CAA-2F03-4DF6-9EC4-0D5882409C31Q35975481-280E358F-F666-4D10-AE89-485C184C859AQ36075753-D66DD49A-7548-466A-BCD6-442EF772E598
P2860
Properdin can initiate complement activation by binding specific target surfaces and providing a platform for de novo convertase assembly.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh-hant
name
Properdin can initiate complem ...... r de novo convertase assembly.
@en
Properdin can initiate complem ...... r de novo convertase assembly.
@nl
type
label
Properdin can initiate complem ...... r de novo convertase assembly.
@en
Properdin can initiate complem ...... r de novo convertase assembly.
@nl
prefLabel
Properdin can initiate complem ...... r de novo convertase assembly.
@en
Properdin can initiate complem ...... r de novo convertase assembly.
@nl
P2093
P1476
Properdin can initiate complem ...... r de novo convertase assembly.
@en
P2093
Dennis E Hourcade
Dirk Spitzer
John P Atkinson
Lynne M Mitchell
P304
P356
10.4049/JIMMUNOL.179.4.2600
P407
P577
2007-08-01T00:00:00Z