Hyporesponsiveness of murine B lymphocytes exposed to the filarial nematode secreted product ES-62 in vivo.
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Parasitic Nematode Immunomodulatory Strategies: Recent Advances and PerspectivesThe immunomodulatory parasitic worm product ES-62 reduces lupus-associated accelerated atherosclerosis in a mouse modelThe parasitic worm product ES-62 targets myeloid differentiation factor 88-dependent effector mechanisms to suppress antinuclear antibody production and proteinuria in MRL/lpr miceBrugia malayi Antigen (BmA) Inhibits HIV-1 Trans-Infection but Neither BmA nor ES-62 Alter HIV-1 Infectivity of DC Induced CD4+ Th-Cells.Parasitic helminths tip the balance: potential anti-inflammatory therapies.Signalling mechanisms underlying subversion of the immune response by the filarial nematode secreted product ES-62.Subversion of immune cell signal transduction pathways by the secreted filarial nematode product, ES-62.The helminth product, ES-62, protects against airway inflammation by resetting the Th cell phenotype.Helminth immunoregulation: the role of parasite secreted proteins in modulating host immunity.Parasitic helminths: a pharmacopeia of anti-inflammatory molecules.The Carbohydrate-linked Phosphorylcholine of the Parasitic Nematode Product ES-62 Modulates Complement Activation.The helminth product, ES-62 modulates dendritic cell responses by inducing the selective autophagolysosomal degradation of TLR-transducers, as exemplified by PKCδ.Protection against collagen-induced arthritis in mice afforded by the parasitic worm product, ES-62, is associated with restoration of the levels of interleukin-10-producing B cells and reduced plasma cell infiltration of the joints.Failure of ES-62 to inhibit T-helper type 1 responses to other filarial nematode antigens.In vivo activation of murine peritoneal B1 cells by the filarial nematode phosphorylcholine-containing glycoprotein ES-62.In vivo exposure of murine dendritic cell and macrophage bone marrow progenitors to the phosphorylcholine-containing filarial nematode glycoprotein ES-62 polarizes their differentiation to an anti-inflammatory phenotype.Lack of immunological cross-reactivity between parasite-derived and recombinant forms of ES-62, a secreted protein of Acanthocheilonema viteae.The pathology of Plasmodium chabaudi infection is not ameliorated by the secreted filarial nematode immunomodulatory molecule, ES-62.Effect of activated antigen-specific B cells on ES-62-mediated modulation of effector function of heterologous antigen-specific T cells in vivo.Phosphorylcholine mimics the effects of ES-62 on macrophages and dendritic cells.
P2860
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P2860
Hyporesponsiveness of murine B lymphocytes exposed to the filarial nematode secreted product ES-62 in vivo.
description
2003 nî lūn-bûn
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2003年の論文
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2003年学术文章
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2003年学术文章
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2003年学术文章
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name
Hyporesponsiveness of murine B ...... ecreted product ES-62 in vivo.
@en
Hyporesponsiveness of murine B ...... ecreted product ES-62 in vivo.
@nl
type
label
Hyporesponsiveness of murine B ...... ecreted product ES-62 in vivo.
@en
Hyporesponsiveness of murine B ...... ecreted product ES-62 in vivo.
@nl
prefLabel
Hyporesponsiveness of murine B ...... ecreted product ES-62 in vivo.
@en
Hyporesponsiveness of murine B ...... ecreted product ES-62 in vivo.
@nl
P2093
P2860
P1433
P1476
Hyporesponsiveness of murine B ...... ecreted product ES-62 in vivo.
@en
P2093
Emma H Wilson
John O'Grady
Katrina M Houston
Kirsty S Brown
Margaret M Harnett
Maureen R Deehan
William Harnett
P2860
P304
P356
10.1046/J.1365-2567.2003.01661.X
P577
2003-06-01T00:00:00Z