Design and synthesis of some substrate analogue inhibitors of phospholipase A2 and investigations by NMR and molecular modeling into the binding interactions in the enzyme-inhibitor complex.
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Phospholipase A2 enzymes: physical structure, biological function, disease implication, chemical inhibition, and therapeutic interventionAmino Acid Derivatives as Palmitoylethanolamide Prodrugs: Synthesis, In Vitro Metabolism and In Vivo Plasma Profile in RatsQuantum-dynamical picture of a multistep enzymatic process: reaction catalyzed by phospholipase A(2).A review on the strategies for the development and application of new anti-arthritic agents.The binding of amide substrate analogues to phospholipase A2. Studies by 13C-nuclear-magnetic-resonance and infrared spectroscopy.Changes in the structure of bovine phospholipase A2 upon micelle bindingDifferential effects of arachidonoyl trifluoromethyl ketone on arachidonic acid release and lipid mediator biosynthesis by human neutrophils. Evidence for different arachidonate pools.Computational evaluation of some indenopyrazole derivatives as anticancer compounds; application of QSAR and docking methodologies.pCRP-mCRP Dissociation Mechanisms as Potential Targets for the Development of Small-Molecule Anti-Inflammatory Chemotherapeutics.
P2860
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P2860
Design and synthesis of some substrate analogue inhibitors of phospholipase A2 and investigations by NMR and molecular modeling into the binding interactions in the enzyme-inhibitor complex.
description
1992 nî lūn-bûn
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1992年の論文
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1992年学术文章
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1992年学术文章
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1992年学术文章
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1992年学术文章
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1992年学术文章
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1992年学术文章
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1992年學術文章
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name
Design and synthesis of some s ...... the enzyme-inhibitor complex.
@en
Design and synthesis of some s ...... the enzyme-inhibitor complex.
@nl
type
label
Design and synthesis of some s ...... the enzyme-inhibitor complex.
@en
Design and synthesis of some s ...... the enzyme-inhibitor complex.
@nl
prefLabel
Design and synthesis of some s ...... the enzyme-inhibitor complex.
@en
Design and synthesis of some s ...... the enzyme-inhibitor complex.
@nl
P2093
P356
P1476
Design and synthesis of some s ...... the enzyme-inhibitor complex.
@en
P2093
C G Jackson
D H Robinson
N P Gensmantel
P K Slaich
S Connolly
W U Primrose
P304
P356
10.1021/JM00094A003
P407
P577
1992-08-01T00:00:00Z