Angiotensin AT4 ligands are potent, competitive inhibitors of insulin regulated aminopeptidase (IRAP).
about
Identification of human aminopeptidase O, a novel metalloprotease with structural similarity to aminopeptidase B and leukotriene A4 hydrolaseEnzymatic properties of human aminopeptidase A. Regulation of its enzymatic activity by calcium and angiotensin IVAngiotensin type 1a receptors on corticotropin-releasing factor neurons contribute to the expression of conditioned fearInvolvement of the somatostatin-2 receptor in the anti-convulsant effect of angiotensin IV against pilocarpine-induced limbic seizures in ratsAssessment of biological activity of novel peptide analogues of angiotensin IV.Development of cognitive enhancers based on inhibition of insulin-regulated aminopeptidase.The impact of ANG II and IV on INS-1 cells and on blood glucose and plasma insulin.Hemoglobin-derived peptides as novel type of bioactive signaling moleculesThe angiotensin IV analog Nle-Tyr-Leu-psi-(CH2-NH2)3-4-His-Pro-Phe (norleual) can act as a hepatocyte growth factor/c-Met inhibitor.Nonclassical renin-angiotensin system and renal function.Discovery of inhibitors of insulin-regulated aminopeptidase as cognitive enhancers.The role of multifunctional M1 metallopeptidases in cell cycle progressionIdentification and development of specific inhibitors for insulin-regulated aminopeptidase as a new class of cognitive enhancers.The role of insulin-regulated aminopeptidase in MHC class I antigen presentation.International Union of Basic and Clinical Pharmacology. XCIX. Angiotensin Receptors: Interpreters of Pathophysiological Angiotensinergic Stimuli [corrected].The oxytocin system in drug discovery for autism: animal models and novel therapeutic strategiesImportance of the brain Angiotensin system in Parkinson's diseaseBiochemical evaluation of the renin-angiotensin system: the good, bad, and absolute?Angiotensin IV upregulates the activity of protein phosphatase 1α in Neura-2A cellsAngiotensin receptor subtype mediated physiologies and behaviors: new discoveries and clinical targets.Central administration of angiotensin IV rapidly enhances novel object recognition among miceNew frontiers in the intrarenal Renin-Angiotensin system: a critical review of classical and new paradigms.The brain renin-angiotensin system: a diversity of functions and implications for CNS diseases.Non-canonical signalling and roles of the vasoactive peptides angiotensins and kinins.Cerebroprotective effects of RAS inhibitors: Beyond their cardio-renal actions.The renin-angiotensin system: a possible new target for depression.Effect of CCR5 receptor antagonists on endocytosis of the human CCR5 receptor in CHO-K1 cellsThe vasoprotective axes of the renin-angiotensin system: Physiological relevance and therapeutic implications in cardiovascular, hypertensive and kidney diseases.Angiotensin IV displays only low affinity for native insulin-regulated aminopeptidase (IRAP).Translocation of the insulin-regulated aminopeptidase to the cell surface: detection by radioligand binding.Identification of modulating residues defining the catalytic cleft of insulin-regulated aminopeptidase.Exciting challenges ahead for integrative physiology27-Hydroxycholesterol impairs neuronal glucose uptake through an IRAP/GLUT4 system dysregulation.Crystal structure of human insulin-regulated aminopeptidase with specificity for cyclic peptides.Metal ion modulation of cystinyl aminopeptidase.Inhibition of Insulin-Regulated Aminopeptidase (IRAP) by Arylsulfonamides.Conformational constraints in angiotensin IV to probe the role of Tyr², Pro⁵ and Phe⁶.Insulin-regulated aminopeptidase: analysis of peptide substrate and inhibitor binding to the catalytic domain.Patent Highlights October-November 2016.
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P2860
Angiotensin AT4 ligands are potent, competitive inhibitors of insulin regulated aminopeptidase (IRAP).
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh-hant
name
Angiotensin AT4 ligands are po ...... gulated aminopeptidase (IRAP).
@en
Angiotensin AT4 ligands are po ...... gulated aminopeptidase (IRAP).
@nl
type
label
Angiotensin AT4 ligands are po ...... gulated aminopeptidase (IRAP).
@en
Angiotensin AT4 ligands are po ...... gulated aminopeptidase (IRAP).
@nl
prefLabel
Angiotensin AT4 ligands are po ...... gulated aminopeptidase (IRAP).
@en
Angiotensin AT4 ligands are po ...... gulated aminopeptidase (IRAP).
@nl
P2093
P1476
Angiotensin AT4 ligands are po ...... gulated aminopeptidase (IRAP).
@en
P2093
Anthony L Albiston
Rebecca A Lew
Sharon G McDowall
Siew Yeen Chai
Tomris Mustafa
P304
P356
10.1046/J.1471-4159.2003.01852.X
P407
P50
P577
2003-07-01T00:00:00Z