Widespread failure of hematolymphoid differentiation caused by a recessive niche-filling allele of the Ikaros transcription factor.
about
Cell cycle-specific function of Ikaros in human leukemiaSelective regulation of lymphopoiesis and leukemogenesis by individual zinc fingers of IkarosRole of Ikaros in T-cell acute lymphoblastic leukemiaA global role for EKLF in definitive and primitive erythropoiesisSignaling advances from immunogenetics to immunogenomicsChallenging the axiom: does the occurrence of oncogenic mutations truly limit cancer development with age?Mutation of l7Rn3 shows that Odz4 is required for mouse gastrulationCell-type-specific activation and repression of PU.1 by a complex of discrete, functionally specialized cis-regulatory elementsLoss of B Cells in Patients with Heterozygous Mutations in IKAROS.Male hypogonadism and germ cell loss caused by a mutation in Polo-like kinase 4.Zebrafish in hematology: sushi or science?Impact of the c-MybE308G mutation on mouse myelopoiesis and dendritic cell development.Dissecting mammalian immunity through mutation.Notch activation is an early and critical event during T-Cell leukemogenesis in Ikaros-deficient miceRegulator of myeloid differentiation and function: The secret life of Ikaros.Vasoactive intestinal peptide signaling axis in human leukemia.The IKAROS interaction with a complex including chromatin remodeling and transcription elongation activities is required for hematopoiesis.The zebrafish: a new model of T-cell and thymic development.Self-renewal of the long-term reconstituting subset of hematopoietic stem cells is regulated by Ikaros.Transcriptional networks in developing and mature B cells.The art and design of genetic screens: mouse.Mouse models for genes involved in impaired spermatogenesis.The use of genomewide ENU mutagenesis screens to unravel complex mammalian traits: identifying genes that regulate organ-specific and systemic autoimmunity.Function of Ikaros as a tumor suppressor in B cell acute lymphoblastic leukemiaHelios marks strongly autoreactive CD4+ T cells in two major waves of thymic deletion distinguished by induction of PD-1 or NF-κB.Ikaros promotes early-born neuronal fates in the cerebral cortex.Recurrent deletions of IKZF1 in pediatric acute myeloid leukemiaIkaros inhibits megakaryopoiesis through functional interaction with GATA-1 and NOTCH signalingActivated Notch counteracts Ikaros tumor suppression in mouse and human T-cell acute lymphoblastic leukemia.Multispectral imaging of hematopoietic cells: where flow meets morphology.Ikaros is required to survive positive selection and to maintain clonal diversity during T-cell development in the thymus.Variations in mRNA and protein levels of Ikaros family members in pediatric T cell acute lymphoblastic leukemia.Evaluation of the long-term reconstituting subset of hematopoietic stem cells with CD150Ikaros in immune receptor signaling, lymphocyte differentiation, and function.B-lineage transcription factors and cooperating gene lesions required for leukemia development.Mouse genetics in drug target discovery and validation: no simple answers to complex problems.B cell biology: an overview.Ikaros fingers on lymphocyte differentiation.Ikaros and leukaemia.Origin and Role of a Subset of Tumor-Associated Neutrophils with Antigen-Presenting Cell Features in Early-Stage Human Lung Cancer.
P2860
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P2860
Widespread failure of hematolymphoid differentiation caused by a recessive niche-filling allele of the Ikaros transcription factor.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh-hant
name
Widespread failure of hematoly ...... e Ikaros transcription factor.
@en
Widespread failure of hematoly ...... e Ikaros transcription factor.
@nl
type
label
Widespread failure of hematoly ...... e Ikaros transcription factor.
@en
Widespread failure of hematoly ...... e Ikaros transcription factor.
@nl
prefLabel
Widespread failure of hematoly ...... e Ikaros transcription factor.
@en
Widespread failure of hematoly ...... e Ikaros transcription factor.
@nl
P2093
P1433
P1476
Widespread failure of hematoly ...... e Ikaros transcription factor.
@en
P2093
Bradley S Cobb
Christopher C Goodnow
Keats A Nelms
Peter Papathanasiou
Roger Ferrini
Rupa Sridharan
Stephen T Smale
P304
P356
10.1016/S1074-7613(03)00168-7
P407
P577
2003-07-01T00:00:00Z