Strikingly homologous immunoglobulin gene rearrangements and poor outcome in VH3-21-using chronic lymphocytic leukemia patients independent of geographic origin and mutational status. - Wikidata - wikimedia - TriplyDB

Strikingly homologous immunoglobulin gene rearrangements and poor outcome in VH3-21-using chronic lymphocytic leukemia patients independent of geographic origin and mutational status.

Strikingly homologous immunoglobulin gene rearrangements and poor outcome in VH3-21-using chronic lymphocytic leukemia patients independent of geographic origin and mutational status.

http://www.wikidata.org/entity/Q44556743

about

Chronic lymphocytic leukaemia: an overview of aetiology in light of recent developments in classification and pathogenesis Guidelines for the diagnosis and treatment of chronic lymphocytic leukemia: a report from the International Workshop on Chronic Lymphocytic Leukemia updating the National Cancer Institute-Working Group 1996 guidelines Deciphering the molecular landscape in chronic lymphocytic leukemia: time frame of disease evolution Immunological aspects in chronic lymphocytic leukemia (CLL) development New mutations in chronic lymphocytic leukemia identified by target enrichment and deep sequencing Stereotypical chronic lymphocytic leukemia B-cell receptors recognize survival promoting antigens on stromal cells.Gene expression factors as predictors of genetic risk and survival in chronic lymphocytic leukemia Clinical laboratory analysis of immunoglobulin heavy chain variable region genes for chronic lymphocytic leukemia prognosis.B-cell receptor epitope recognition correlates with the clinical course of chronic lymphocytic leukemia.Convergent antibody signatures in human dengue High-density screening reveals a different spectrum of genomic aberrations in chronic lymphocytic leukemia patients with 'stereotyped' IGHV3-21 and IGHV4-34 B-cell receptors.Prognostic factors identified three risk groups in the LRF CLL4 trial, independent of treatment allocation Protein expression analysis of chronic lymphocytic leukemia defines the effect of genetic aberrations and uncovers a correlation of CDK4, P27 and P53 with hierarchical risk Predicting survival in chronic lymphocytic leukemia.Prognostic information and biological insights in chronic lymphocytic leukemia by high-resolution immunophenotypic analysis of ZAP70.LDOC1 mRNA is differentially expressed in chronic lymphocytic leukemia and predicts overall survival in untreated patients.Not all IGHV3-21 chronic lymphocytic leukemias are equal: prognostic considerations Targeted next-generation sequencing in chronic lymphocytic leukemia: a high-throughput yet tailored approach will facilitate implementation in a clinical setting.Respiratory tract infections and subsequent risk of chronic lymphocytic leukemia.Naive antibody gene-segment frequencies are heritable and unaltered by chronic lymphocyte ablation.Patterns of autoimmunity and subsequent chronic lymphocytic leukemia in Nordic countries.Immunoglobulin diversity gene usage predicts unfavorable outcome in a subset of chronic lymphocytic leukemia patients.Distinct transcriptional control in major immunogenetic subsets of chronic lymphocytic leukemia exhibiting subset-biased global DNA methylation profiles.Use of IGHV3-21 in chronic lymphocytic leukemia is associated with high-risk disease and reflects antigen-driven, post-germinal center leukemogenic selection.The immunoglobulin genes: structure and specificity in chronic lymphocytic leukemia.Multiple myeloma, chronic lymphocytic leukaemia and associated precursor diseases.Prognostic impact of epigenetic classification in chronic lymphocytic leukemia: The case of subset #2.Temporal dynamics of clonal evolution in chronic lymphocytic leukemia with stereotyped IGHV4-34/IGKV2-30 antigen receptors: longitudinal immunogenetic evidence.Computational identification of CDR3 sequence archetypes among immunoglobulin sequences in chronic lymphocytic leukemia.Intrinsic and extrinsic factors influencing the clinical course of B-cell chronic lymphocytic leukemia: prognostic markers with pathogenetic relevance.B-cell receptor, clinical course and prognosis in chronic lymphocytic leukaemia: the growing saga of the IGHV3 subgroup gene usage.Immunoglobulin sequence analysis and prognostication in CLL: guidelines from the ERIC review board for reliable interpretation of problematic cases.Can prognostic factors be used to direct therapy in chronic lymphocytic leukemia?Geography, ethnicity and "roots" in chronic lymphocytic leukemia.Prognostic markers and their clinical applicability in chronic lymphocytic leukemia: where do we stand?The role of chemotherapy in managing chronic lymphocytic leukemia: optimizing combinations with targeted therapy.Stereotyped B-cell receptors in chronic lymphocytic leukemia.Analysis of chronic lymphotic leukemia transcriptomic profile: differences between molecular subgroups.Whole-genome sequencing of chronic lymphocytic leukaemia reveals distinct differences in the mutational landscape between IgHVmut and IgHVunmut subgroups.Evaluation of serum markers in the LRF CLL4 trial: β2-microglobulin but not serum free light chains, is an independent marker of overall survival.

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Strikingly homologous immunoglobulin gene rearrangements and poor outcome in VH3-21-using chronic lymphocytic leukemia patients independent of geographic origin and mutational status.

http://www.wikidata.org/entity/Q44556743

description

2005 nî lūn-bûn

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2005年の論文

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2005年学术文章

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2005年学术文章

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2005年学术文章

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2005年学术文章

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2005年学术文章

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2005年学术文章

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2005年學術文章

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2005年學術文章

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name

Strikingly homologous immunogl ...... origin and mutational status.

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Strikingly homologous immunogl ...... origin and mutational status.

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type

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Strikingly homologous immunogl ...... origin and mutational status.

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Strikingly homologous immunogl ...... origin and mutational status.

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Strikingly homologous immunogl ...... origin and mutational status.

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Strikingly homologous immunogl ...... origin and mutational status.

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BLOOD-2005-06-2227

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Strikingly homologous immunogl ...... origin and mutational status.

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Alexander Kröber

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Andreas Bühler

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Anna Laurell

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Dirk Kienle

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Emilia Albesiano

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Juhani Vilpo

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scholarly article

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10.1182/BLOOD-2005-06-2227

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