Stress-induced apoptosis is impaired in cells with a lysosomal targeting defect but is not affected in cells synthesizing a catalytically inactive cathepsin D.
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The Potential Role of the Proteases Cathepsin D and Cathepsin L in the Progression and Metastasis of Epithelial Ovarian CancerCathepsin D--many functions of one aspartic proteaseGlycogen Synthase Kinase-3β and Caspase-2 Mediate Ceramide- and Etoposide-Induced Apoptosis by Regulating the Lysosomal-Mitochondrial Axis.Overexpression of both catalytically active and -inactive cathepsin D by cancer cells enhances apoptosis-dependent chemo-sensitivityProtease signalling in cell death: caspases versus cysteine cathepsins.Cathepsin D overexpressed by cancer cells can enhance apoptosis-dependent chemo-sensitivity independently of its catalytic activity.Cathepsin D expression level affects alpha-synuclein processing, aggregation, and toxicity in vivo.Lysosomes as "suicide bags" in cell death: myth or reality?Enzymatically active cathepsin D sensitizes breast carcinoma cells to TRAIL.Yeast as a tool to explore cathepsin D function.Mannose 6-phosphorylated proteins are required for tumor necrosis factor-induced apoptosis: defective response in I-cell disease fibroblasts.Human herpesvirus 8 interleukin-6 contributes to primary effusion lymphoma cell viability via suppression of proapoptotic cathepsin D, a cointeraction partner of vitamin K epoxide reductase complex subunit 1 variant 2.
P2860
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P2860
Stress-induced apoptosis is impaired in cells with a lysosomal targeting defect but is not affected in cells synthesizing a catalytically inactive cathepsin D.
description
2003 nî lūn-bûn
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name
Stress-induced apoptosis is im ...... ytically inactive cathepsin D.
@en
Stress-induced apoptosis is im ...... ytically inactive cathepsin D.
@nl
type
label
Stress-induced apoptosis is im ...... ytically inactive cathepsin D.
@en
Stress-induced apoptosis is im ...... ytically inactive cathepsin D.
@nl
prefLabel
Stress-induced apoptosis is im ...... ytically inactive cathepsin D.
@en
Stress-induced apoptosis is im ...... ytically inactive cathepsin D.
@nl
P2093
P2860
P356
P1476
Stress-induced apoptosis is im ...... ytically inactive cathepsin D.
@en
P2093
Andrieu-Abadie N
P2860
P2888
P304
P356
10.1038/SJ.CDD.4401272
P577
2003-09-01T00:00:00Z
P5875
P6179
1046696315