Effects of activation peptide bond cleavage and fragment 2 interactions on the pathway of exosite I expression during activation of human prethrombin 1 to thrombin.

Effects of activation peptide bond cleavage and fragment 2 interactions on the pathway of exosite I expression during activation of human prethrombin 1 to thrombin.

Item
http://www.wikidata.org/entity/Q44562077
Active site-labeled prothrombin inhibits prothrombinase in vitro and thrombosis in vivo.Effect of zymogen domains and active site occupation on activation of prothrombin by von Willebrand factor-binding protein.Expression of allosteric linkage between the sodium ion binding site and exosite I of thrombin during prothrombin activation.Exosites in the substrate specificity of blood coagulation reactions.The transition of prothrombin to thrombin.Mutagenesis studies toward understanding allostery in thrombin.HD1, a thrombin-directed aptamer, binds exosite 1 on prothrombin with high affinity and inhibits its activation by prothrombinase.Fate of membrane-bound reactants and products during the activation of human prothrombin by prothrombinase.Amide H/2H exchange reveals a mechanism of thrombin activation.Role of prothrombin fragment 1 in the pathway of regulatory exosite I formation during conversion of human prothrombin to thrombin.Active site-independent recognition of substrates and product by bovine prothrombinase: a fluorescence resonance energy transfer study.A control switch for prothrombinase: characterization of a hirudin-like pentapeptide from the COOH terminus of factor Va heavy chain that regulates the rate and pathway for prothrombin activation.The structural integrity of anion binding exosite I of thrombin is required and sufficient for timely cleavage and activation of factor V and factor VIII.
P2860

Effects of activation peptide bond cleavage and fragment 2 interactions on the pathway of exosite I expression during activation of human prethrombin 1 to thrombin.

Item
http://www.wikidata.org/entity/Q44562077
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh-hant
name
Effects of activation peptide ...... man prethrombin 1 to thrombin.
@en
Effects of activation peptide ...... man prethrombin 1 to thrombin.
@nl
type
label
Effects of activation peptide ...... man prethrombin 1 to thrombin.
@en
Effects of activation peptide ...... man prethrombin 1 to thrombin.
@nl
prefLabel
Effects of activation peptide ...... man prethrombin 1 to thrombin.
@en
Effects of activation peptide ...... man prethrombin 1 to thrombin.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698
P356
P1433
P1476
Effects of activation peptide ...... man prethrombin 1 to thrombin.
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698