Sphingosine kinase 2 is a nuclear protein and inhibits DNA synthesis. - Wikidata - wikimedia - TriplyDB

Sphingosine kinase 2 is a nuclear protein and inhibits DNA synthesis.

Sphingosine kinase 2 is a nuclear protein and inhibits DNA synthesis.

http://www.wikidata.org/entity/Q44572814

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FHL2/SLIM3 decreases cardiomyocyte survival by inhibitory interaction with sphingosine kinase-1 Sphingosine 1-phosphate as a regulator of osteoclast differentiation and osteoclast-osteoblast coupling Overexpression of CERKL, a gene responsible for retinitis pigmentosa in humans, protects cells from apoptosis induced by oxidative stress An overview of sphingolipid metabolism: from synthesis to breakdown A house divided: ceramide, sphingosine, and sphingosine-1-phosphate in programmed cell death The emerging role of FTY720 (Fingolimod) in cancer treatment Trafficking and Functions of Bioactive Sphingolipids: Lessons from Cells and Model Membranes Sphingolipids in High Fat Diet and Obesity-Related Diseases Evolving concepts in cancer therapy through targeting sphingolipid metabolism The compartmentalization and translocation of the sphingosine kinases: mechanisms and functions in cell signaling and sphingolipid metabolism S1P control of endothelial integrity Sphingolipids in spinal cord injury Fingolimod for the treatment of neurological diseases-state of play and future perspectives Sphingosine kinase 1 is a reliable prognostic factor and a novel therapeutic target for uterine cervical cancer.Silencing diacylglycerol kinase-theta expression reduces steroid hormone biosynthesis and cholesterol metabolism in human adrenocortical cells Characterization of isoenzyme-selective inhibitors of human sphingosine kinases Biological characterization of 3-(2-amino-ethyl)-5-[3-(4-butoxyl-phenyl)-propylidene]-thiazolidine-2,4-dione (K145) as a selective sphingosine kinase-2 inhibitor and anticancer agent Essential role for sphingosine kinases in neural and vascular development Involvement of sphingosine-1-phosphate in glutamate secretion in hippocampal neurons Transcription factor specificity protein 1 (Sp1) is the main regulator of nerve growth factor-induced sphingosine kinase 1 gene expression of the rat pheochromocytoma cell line, PC12 Transforming Sphingosine Kinase 1 Inhibitors into Dual and Sphingosine Kinase 2 Selective Inhibitors: Design, Synthesis, and in Vivo Activity.Sphingosine Kinase 2 Deficiency Attenuates Kidney Fibrosis via IFN-γ.Structural Requirements and Docking Analysis of Amidine-Based Sphingosine Kinase 1 Inhibitors Containing Oxadiazoles.Structure-activity relationship studies and in vivo activity of guanidine-based sphingosine kinase inhibitors: discovery of SphK1- and SphK2-selective inhibitors.Sphingosine kinase type 2 inhibition elevates circulating sphingosine 1-phosphate.Design, synthesis and biological activity of sphingosine kinase 2 selective inhibitors.Divergent roles of sphingosine kinases in kidney ischemia-reperfusion injury.Sphingosine-1-phosphate receptors: biology and therapeutic potential in kidney disease Active, phosphorylated fingolimod inhibits histone deacetylases and facilitates fear extinction memory.A strategy for enrichment of claudins based on their affinity to Clostridium perfringens enterotoxin The expression of sphingosine kinase-1 in head and neck carcinoma Re-configuration of sphingolipid metabolism by oncogenic transformation.Essential roles of neutral ceramidase and sphingosine in mitochondrial dysfunction due to traumatic brain injury.Sphingosine kinase and sphingosine 1-phosphate in cardioprotection.Expression and regulation of enzymes in the ceramide metabolic pathway in human retinal pigment epithelial cells and their relevance to retinal degeneration.Estradiol induces export of sphingosine 1-phosphate from breast cancer cells via ABCC1 and ABCG2.Mammalian sphingosine kinase (SphK) isoenzymes and isoform expression: challenges for SphK as an oncotarget.Sphingosine kinase: Role in regulation of bioactive sphingolipid mediators in inflammation.Sphingosine kinase mediates resistance to the synthetic retinoid N-(4-hydroxyphenyl)retinamide in human ovarian cancer cells.The sphingosine 1-phosphate transporter, SPNS2, functions as a transporter of the phosphorylated form of the immunomodulating agent FTY720.

P2860

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P2860

Sphingosine kinase 2 is a nuclear protein and inhibits DNA synthesis.

http://www.wikidata.org/entity/Q44572814

description

2003 nî lūn-bûn

@nan

2003年の論文

@ja

2003年学术文章

@wuu

2003年学术文章

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2003年学术文章

@zh-cn

2003年学术文章

@zh-hans

2003年学术文章

@zh-my

2003年学术文章

@zh-sg

2003年學術文章

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2003年學術文章

@zh-hant

name

Sphingosine kinase 2 is a nuclear protein and inhibits DNA synthesis.

@en

Sphingosine kinase 2 is a nuclear protein and inhibits DNA synthesis.

@nl

type

label

Sphingosine kinase 2 is a nuclear protein and inhibits DNA synthesis.

@en

Sphingosine kinase 2 is a nuclear protein and inhibits DNA synthesis.

@nl

prefLabel

Sphingosine kinase 2 is a nuclear protein and inhibits DNA synthesis.

@en

Sphingosine kinase 2 is a nuclear protein and inhibits DNA synthesis.

@nl

P1433

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P1433

Journal of Biological Chemistry

P1476

Sphingosine kinase 2 is a nuclear protein and inhibits DNA synthesis.

@en

P2093

Nobuaki Igarashi

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Saleem Jahangeer

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Shun Hayashi

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Shun-ichi Nakamura

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Taro Okada

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Toshitada Fujita

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46832-46839

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scholarly article

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10.1074/JBC.M306577200

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47

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278

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2003-09-02T00:00:00Z

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12954646

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