Design and synthesis of pyrrolidine-5,5'-trans-lactams (5-oxo-hexahydropyrrolo[3,2-b]pyrroles) as novel mechanism-based inhibitors of human cytomegalovirus protease. 4. Antiviral activity and plasma stability.
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Current and potential treatments for ubiquitous but neglected herpesvirus infectionsEthyl 1-(4-methoxy-phen-yl)-2-nitro-3-[4-oxo-3-phenyl-1-(4-methoxy-phen-yl)azetidin-2-yl]-2,3,10,10a-tetra-hydro-1H,5H-pyrrolo[1,2-b]isoquinoline-10a-carboxyl-ateAmmonia synthons for the multicomponent assembly of complex gamma-lactams.KSHV targeted therapy: an update on inhibitors of viral lytic replication.Predicting the Enzymatic Hydrolysis Half-lives of New Chemicals Using Support Vector Regression Models Based on Stepwise Feature Elimination.The road to avibactam: the first clinically useful non-β-lactam working somewhat like a β-lactam.Utility of the carboxylesterase inhibitor bis-para-nitrophenylphosphate (BNPP) in the plasma unbound fraction determination for a hydrolytically unstable amide derivative and agonist of the TGR5 receptor.
P2860
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P2860
Design and synthesis of pyrrolidine-5,5'-trans-lactams (5-oxo-hexahydropyrrolo[3,2-b]pyrroles) as novel mechanism-based inhibitors of human cytomegalovirus protease. 4. Antiviral activity and plasma stability.
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2003 nî lūn-bûn
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2003年の論文
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2003年学术文章
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2003年学术文章
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name
Design and synthesis of pyrrol ...... activity and plasma stability.
@en
Design and synthesis of pyrrol ...... activity and plasma stability.
@nl
type
label
Design and synthesis of pyrrol ...... activity and plasma stability.
@en
Design and synthesis of pyrrol ...... activity and plasma stability.
@nl
prefLabel
Design and synthesis of pyrrol ...... activity and plasma stability.
@en
Design and synthesis of pyrrol ...... activity and plasma stability.
@nl
P2093
P356
P1476
Design and synthesis of pyrrol ...... activity and plasma stability.
@en
P2093
Alan D Borthwick
Angela Patikis
Anne M Exall
Dave E Davies
Deborah L Jackson
Gordon G Weingarten
Graham J Hart
James M Woolven
Naimisha Trivedi
Nigel R Parry
P304
P356
10.1021/JM030810W
P407
P577
2003-10-01T00:00:00Z