Levels of PTEN protein modulate Akt phosphorylation on serine 473, but not on threonine 308, in IGF-II-overexpressing rhabdomyosarcomas cells.
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CCI-779 inhibits rhabdomyosarcoma xenograft growth by an antiangiogenic mechanism linked to the targeting of mTOR/Hif-1alpha/VEGF signalingPhenotype selection reveals coevolution of muscle glycogen and protein and PTEN as a gate keeper for the accretion of muscle mass in adult female mice11β-HSD1 modulates LPS-induced innate immune responses in adipocytes by altering expression of PTEN.Proteomic and phosphoproteomic alterations in benign, premalignant and tumor human breast epithelial cells and xenograft lesions: biomarkers of progressionIdentification of FoxM1/Bub1b signaling pathway as a required component for growth and survival of rhabdomyosarcoma.Expression, signaling proficiency, and stimulatory function of the NKG2D lymphocyte receptor in human cancer cells.Combination testing (Stage 2) of the Anti-IGF-1 receptor antibody IMC-A12 with rapamycin by the pediatric preclinical testing program.IGF-1R Inhibition Activates a YES/SFK Bypass Resistance Pathway: Rational Basis for Co-Targeting IGF-1R and Yes/SFK Kinase in Rhabdomyosarcoma.Decreased spermatogenesis, fertility, and altered Slc2A expression in Akt1-/- and Akt2-/- testes and sperm.MicroRNA-26b Modulates the NF-κB Pathway in Alveolar Macrophages by Regulating PTEN.FOXO1a acts as a selective tumor suppressor in alveolar rhabdomyosarcoma.Regulation of airway and alveolar epithelial cell apoptosis by p53-Induced plasminogen activator inhibitor-1 during cigarette smoke exposure injuryTissue and serum IGFBP7 protein as biomarker in high-grade soft tissue sarcomaOverexpression of cyclin B1 antagonizes chemotherapeutic-induced apoptosis through PTEN/Akt pathway in human esophageal squamous cell carcinoma cellsAn extract of Urtica dioica L. mitigates obesity induced insulin resistance in mice skeletal muscle via protein phosphatase 2A (PP2A).SLC9A3R1 stimulates autophagy via BECN1 stabilization in breast cancer cellsThe p21-activated kinase, PAK2, is important in the activation of numerous pancreatic acinar cell signaling cascades and in the onset of early pancreatitis eventsCell survival and metastasis regulation by Akt signaling in colorectal cancerThe basal level of intracellular calcium gates the activation of phosphoinositide 3-kinase-Akt signaling by brain-derived neurotrophic factor in cortical neuronsTBX2 represses PTEN in rhabdomyosarcoma and skeletal muscle.PTEN negatively regulates mTORC2 formation and signaling in grade IV glioma via Rictor hyperphosphorylation at Thr1135 and direct the mode of action of an mTORC1/2 inhibitor.Tat-induced FOXO3a is a key mediator of apoptosis in HIV-1-infected human CD4+ T lymphocytes.Addiction to elevated insulin-like growth factor I receptor and initial modulation of the AKT pathway define the responsiveness of rhabdomyosarcoma to the targeting antibody.JNK1 determines the oncogenic or tumor-suppressive activity of the integrin-linked kinase in human rhabdomyosarcomaAge-associated impairment of Akt phosphorylation in primary rat hepatocytes is remediated by alpha-lipoic acid through PI3 kinase, PTEN, and PP2A.Beta4 integrin promotes osteosarcoma metastasis and interacts with ezrin.Musashi-1 regulates AKT-derived IL-6 autocrinal/paracrinal malignancy and chemoresistance in glioblastomaTargeted therapy for sarcomas.The emerging role of mammalian target of rapamycin inhibitors in the treatment of sarcomas.The antitumor effect of GDC-0941 alone and in combination with rapamycin in breast cancer cells.Expression of insulin-like growth factor pathway proteins in rhabdomyosarcoma: IGF-2 expression is associated with translocation-negative tumors.miR-718 represses proinflammatory cytokine production through targeting phosphatase and tensin homolog (PTEN).Modeling Protein Expression and Protein Signaling Pathways.MicroRNA 152 regulates hepatic glycogenesis by targeting PTEN.Baicalein inhibits pancreatic cancer cell proliferation and invasion via suppression of NEDD9 expression and its downstream Akt and ERK signaling pathways.Signaling mechanisms involved in altered function of macrophages from diet-induced obese mice affect immune responses.Regional hippocampal differences in AKT survival signaling across the lifespan: implications for CA1 vulnerability with aging.Conditional deletion of Pten causes bronchiolar hyperplasia.Regulation of axonal growth and neuromuscular junction formation by neuronal phosphatase and tensin homologue signalingMice lacking dystrophin or alpha sarcoglycan spontaneously develop embryonal rhabdomyosarcoma with cancer-associated p53 mutations and alternatively spliced or mutant Mdm2 transcripts.
P2860
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P2860
Levels of PTEN protein modulate Akt phosphorylation on serine 473, but not on threonine 308, in IGF-II-overexpressing rhabdomyosarcomas cells.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh-hant
name
Levels of PTEN protein modulat ...... ssing rhabdomyosarcomas cells.
@en
Levels of PTEN protein modulat ...... ssing rhabdomyosarcomas cells.
@nl
type
label
Levels of PTEN protein modulat ...... ssing rhabdomyosarcomas cells.
@en
Levels of PTEN protein modulat ...... ssing rhabdomyosarcomas cells.
@nl
prefLabel
Levels of PTEN protein modulat ...... ssing rhabdomyosarcomas cells.
@en
Levels of PTEN protein modulat ...... ssing rhabdomyosarcomas cells.
@nl
P2860
P356
P1433
P1476
Levels of PTEN protein modulat ...... ssing rhabdomyosarcomas cells.
@en
P2093
Lee J Helman
Xiaolin Wan
P2860
P2888
P304
P356
10.1038/SJ.ONC.1206878
P407
P577
2003-11-01T00:00:00Z