Disruption of mptpB impairs the ability of Mycobacterium tuberculosis to survive in guinea pigs.
about
Deciphering the roles of phosphoinositide lipids in phagolysosome biogenesisSmall molecule tools for functional interrogation of protein tyrosine phosphatasesPhosphoinositides: tiny lipids with giant impact on cell regulationStructural Basis for Selective Inhibition of Mycobacterium tuberculosis Protein Tyrosine Phosphatase PtpBThe TriTryp phosphatome: analysis of the protein phosphatase catalytic domainsProtein tyrosine phosphatases and the immune responseDevelopment of the first oligonucleotide microarray for global gene expression profiling in guinea pigs: defining the transcription signature of infectious diseasesNuclear localization and in situ DNA damage by Mycobacterium tuberculosis nucleoside-diphosphate kinaseDiscovery of Mycobacterium tuberculosis protein tyrosine phosphatase B (PtpB) inhibitors from natural productsMycobacterial MazG safeguards genetic stability via housecleaning of 5-OH-dCTPStringent homology-based prediction of H. sapiens-M. tuberculosis H37Rv protein-protein interactions.Discovery of Mycobacterium tuberculosis protein tyrosine phosphatase A (MptpA) inhibitors based on natural products and a fragment-based approach.Enhanced and enduring protection against tuberculosis by recombinant BCG-Ag85C and its association with modulation of cytokine profile in lung.Inhibition of MptpB phosphatase from Mycobacterium tuberculosis impairs mycobacterial survival in macrophages.Targeting mycobacterium protein tyrosine phosphatase B for antituberculosis agents.A new family of phosphoinositide phosphatases in microorganisms: identification and biochemical analysisFrom mouth to macrophage: mechanisms of innate immune subversion by Mycobacterium avium subsp. paratuberculosis.Structural insights into mode of actions of novel natural Mycobacterium protein tyrosine phosphatase B inhibitors.Dynamic active-site protection by the M. tuberculosis protein tyrosine phosphatase PtpB lid domain.Requirement of the mymA operon for appropriate cell wall ultrastructure and persistence of Mycobacterium tuberculosis in the spleens of guinea pigs.Microwave-assisted synthesis of small molecules targeting the infectious diseases tuberculosis, HIV/AIDS, malaria and hepatitis C.Exploring anti-TB leads from natural products library originated from marine microbes and medicinal plants.Identification and characterization of novel inhibitors of mPTPB, an essential virulent phosphatase from Mycobacterium tuberculosis.Design and synthesis of nonpeptidic, small molecule inhibitors for the Mycobacterium tuberculosis protein tyrosine phosphatase PtpBMycobacterium tuberculosis Serine/Threonine Protein Kinases.A facile hydroxyindole carboxylic acid based focused library approach for potent and selective inhibitors of Mycobacterium protein tyrosine phosphatase BAsperlones A and B, dinaphthalenone derivatives from a mangrove endophytic fungus Aspergillus sp. 16-5C.Secretory phosphatases deficient mutant of Mycobacterium tuberculosis imparts protection at the primary site of infection in guinea pigs.Double click reaction for the acquisition of a highly potent and selective mPTPB inhibitorProtein tyrosine phosphatase PtpA is not required for Mycobacterium tuberculosis growth in mice.PTP-H2 and PTP-H3 from Microplitis demolitor Bracovirus localize to focal adhesions and are antiphagocytic in insect immune cells.Interplay between mycobacteria and host signalling pathways.Recent advances towards identification of new drug targets for Mycobacterium tuberculosis.Bicyclic benzofuran and indole-based salicylic acids as protein tyrosine phosphatase inhibitorsMycobacterium tuberculosis WhiB4 regulates oxidative stress response to modulate survival and dissemination in vivo.Mycobacterial shuttle vectors designed for high-level protein expression in infected macrophages.Systematic Analysis of Mycobacterial Acylation Reveals First Example of Acylation-mediated Regulation of Enzyme Activity of a Bacterial PhosphataseCefsulodin Inspired Potent and Selective Inhibitors of mPTPB, a Virulent Phosphatase from Mycobacterium tuberculosis.Structure/function studies of Ser/Thr and Tyr protein phosphorylation in Mycobacterium tuberculosis.Role of protein phosphorylation on serine/threonine and tyrosine in the virulence of bacterial pathogens.
P2860
Q26739455-163C447F-EC93-4C63-B1D2-576D8359E1D9Q26852276-DC3284A0-C3AA-446C-A006-DC12BC3BEEEBQ27012953-5FB52C8C-2EA5-4506-9075-FBA43E1F8B4BQ27644471-D4D42C49-F4B5-47F0-AD25-CF8D80552A66Q28258708-36448E0B-AE65-4F45-9825-CA9E55B9023EQ28300971-75DB2D95-6E9B-4941-A6E2-5E82F8532F38Q28389922-0C7FDEF6-9158-4D0A-95BB-B740F3D067FDQ28487403-52B4FB06-4302-406F-A634-D3E69A738B7DQ28534388-82355273-2CC6-465E-A608-E7DCED16A689Q28536317-611765C7-0E9E-46DC-8365-A6A78E2855F4Q28660142-7006C646-7D7B-4755-B5AA-B31D27E1317AQ33224289-916F5F0F-4ECE-4E6B-9733-230D10A11F8DQ33389187-5FAA3B93-E490-48F1-BB9D-1EBE29EC808DQ33412046-E80337B2-9B15-43BD-A12D-6E57FCDA9835Q33532352-00E1A03B-87C3-4627-A687-2CCAE79E92BDQ33647356-558B9F8A-8805-4D2B-8198-C83D8CC7100EQ33712909-B645679F-A4DC-4BDC-8848-74AA9C06CB50Q33715761-7C8DC585-A5EF-4748-B167-3A4F04D57044Q33806251-06A4C6FA-AF99-49F8-A236-39383FB99AD6Q33855579-FF04439C-9C08-41AB-BCBE-C20F3F621E3BQ34121361-8CCBEB7C-CCEC-4929-BFC0-5A086C0A245AQ34344261-A193A748-F541-4CBC-9402-AB8F53C807D6Q34353151-B5339495-095E-4416-AD3E-070FBA575093Q34437023-C9D0C25A-DA5B-460D-855C-F6AC9A3BB609Q34565203-71D8C02E-BC31-4FA6-A498-9874422C8048Q34660114-9B12AF7C-C94C-4CC6-A75D-2A8E8448BE40Q35015361-4E19C88E-FF18-4EB3-87E6-8D61C033E78AQ35035800-F882BFB3-BEC9-4F4D-ACC8-F0A07AD1139FQ35052636-447D317F-BC7A-42F2-8672-8D936AB7AD66Q35111162-0E45D125-7205-4C58-AB34-EB0A650E486EQ35635103-FB440A90-1E83-44CA-988F-8AE92254ACEDQ35745231-0452D893-BA85-4B39-9CDD-93A8977D4CA3Q35753354-B0BF84B7-DA3E-4F27-87E8-35075BEFA851Q35815528-043E9ADD-9674-4E78-9BF2-0E7C15D16858Q36223232-19A28DD9-2991-47E1-930A-929F965FB014Q36277210-C19A1FC4-9125-49B1-9702-7EB66EB8DB9AQ36283574-183E47D2-FF63-4141-9C12-81D572ED9E02Q36367311-2DE21EA5-D9CD-4678-B7C3-6CA9739895F5Q36369654-97174FDA-B635-4E8D-B474-3F3F76F0037BQ36369665-456B462A-A57A-4C1A-B941-6FF9E5E47EE1
P2860
Disruption of mptpB impairs the ability of Mycobacterium tuberculosis to survive in guinea pigs.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh-hant
name
Disruption of mptpB impairs th ...... sis to survive in guinea pigs.
@en
Disruption of mptpB impairs th ...... sis to survive in guinea pigs.
@nl
type
label
Disruption of mptpB impairs th ...... sis to survive in guinea pigs.
@en
Disruption of mptpB impairs th ...... sis to survive in guinea pigs.
@nl
prefLabel
Disruption of mptpB impairs th ...... sis to survive in guinea pigs.
@en
Disruption of mptpB impairs th ...... sis to survive in guinea pigs.
@nl
P2093
P2860
P1476
Disruption of mptpB impairs th ...... osis to survive in guinea pigs
@en
P2093
Amit Singh
Anil K Tyagi
Aparna Khera
C N Paramasivan
P R Narayanan
Radhika Gupta
Ramandeep Singh
P2860
P304
P356
10.1046/J.1365-2958.2003.03712.X
P407
P50
P577
2003-11-01T00:00:00Z