The transcription factor Eyes absent is a protein tyrosine phosphatase.
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Tyrosine dephosphorylation of H2AX modulates apoptosis and survival decisionsDephosphorylation of the C-terminal tyrosyl residue of the DNA damage-related histone H2A.X is mediated by the protein phosphatase eyes absentBiochemical and functional characterization of six SIX1 Branchio-oto-renal syndrome mutationsChronophin, a novel HAD-type serine protein phosphatase, regulates cofilin-dependent actin dynamicsMultiple Functions of the Eya Phosphotyrosine PhosphataseRetinal differentiation in DrosophilaCrystal structure of ED-Eya2: insight into dual roles as a protein tyrosine phosphatase and a transcription factorStructure-function analyses of the human SIX1–EYA2 complex reveal insights into metastasis and BOR syndromeEvolutionary and Structural Analyses of Mammalian Haloacid Dehalogenase-type Phosphatases AUM and Chronophin Provide Insight into the Basis of Their Different Substrate SpecificitiesTranscriptional regulation of cranial sensory placode developmentThe DACH/EYA/SIX gene network and its role in tumor initiation and progressionThe EYA tyrosine phosphatase activity is pro-angiogenic and is inhibited by benzbromaroneThe M. tuberculosis HAD phosphatase (Rv3042c) interacts with host proteins and is inhibited by ClofazimineEya 1 acts as a critical regulator for specifying the metanephric mesenchymeSipl1 and Rbck1 are novel Eya1-binding proteins with a role in craniofacial developmentStructure-activity relationships of benzbromarone metabolites and derivatives as EYA inhibitory anti-angiogenic agentsGene Expression Data from the Moon Jelly, Aurelia, Provide Insights into the Evolution of the Combinatorial Code Controlling Animal Sense Organ DevelopmentRetinal Expression of the Drosophila eyes absent Gene Is Controlled by Several Cooperatively Acting Cis-regulatory ElementsEya4-deficient mice are a model for heritable otitis media.Allosteric inhibitors of the Eya2 phosphatase are selective and inhibit Eya2-mediated cell migration.Novel method for high throughput DNA methylation marker evaluation using PNA-probe library hybridization and MALDI-TOF detection.Pleiotropic effects in Eya3 knockout mice.Genetic regulation of pituitary gland development in human and mouseInhibition of Eyes Absent Homolog 4 expression induces malignant peripheral nerve sheath tumor necrosis.The retinal determination gene eyes absent is regulated by the EGF receptor pathway throughout development in Drosophila.EYA1 mutations associated with the branchio-oto-renal syndrome result in defective otic development in Xenopus laevisThe Eyes Absent phosphatase-transactivator proteins promote proliferation, transformation, migration, and invasion of tumor cellsA phosphotyrosine switch determines the antitumor activity of ERβ.Structure and catalytic mechanism of human protein tyrosine phosphatome.VHY, a novel myristoylated testis-restricted dual specificity protein phosphatase related to VHX.Identification of a selective small-molecule inhibitor series targeting the eyes absent 2 (Eya2) phosphatase activity.Drosophila EYA regulates the immune response against DNA through an evolutionarily conserved threonine phosphatase motifMutation in the transcriptional coactivator EYA4 causes dilated cardiomyopathy and sensorineural hearing loss.MAPK target sites of eyes absent are not required for eye development or survival in DrosophilaUsing Drosophila to decipher how mutations associated with human branchio-oto-renal syndrome and optical defects compromise the protein tyrosine phosphatase and transcriptional functions of eyes absentGenome-wide identification of direct targets of the Drosophila retinal determination protein Eyeless.Eyes absent tyrosine phosphatase activity is not required for Drosophila development or survivalThe PI3K/Akt signal hyperactivates Eya1 via the SUMOylation pathway.Targeting protein tyrosine phosphatases for anticancer drug discovery.The Eye Specification Network in Drosophila
P2860
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P2860
The transcription factor Eyes absent is a protein tyrosine phosphatase.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh-hant
name
The transcription factor Eyes absent is a protein tyrosine phosphatase.
@en
The transcription factor Eyes absent is a protein tyrosine phosphatase.
@nl
type
label
The transcription factor Eyes absent is a protein tyrosine phosphatase.
@en
The transcription factor Eyes absent is a protein tyrosine phosphatase.
@nl
prefLabel
The transcription factor Eyes absent is a protein tyrosine phosphatase.
@en
The transcription factor Eyes absent is a protein tyrosine phosphatase.
@nl
P2093
P356
P1433
P1476
The transcription factor Eyes absent is a protein tyrosine phosphatase.
@en
P2093
Beth E W Parlikar
Erin L Davies
Ilaria Rebay
Ishara A Mills
Robert R Latek
Serena J Silver
Tina L Tootle
Victoria Newman
P2888
P304
P356
10.1038/NATURE02097
P407
P577
2003-11-01T00:00:00Z
P5875
P6179
1041702235