Single immunizing dose of recombinant adenovirus efficiently induces CD8+ T cell-mediated protective immunity against malaria.
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Treatment with soluble interleukin-15Ralpha exacerbates intracellular parasitic infection by blocking the development of memory CD8+ T cell responseA glycolipid adjuvant, 7DW8-5, enhances CD8+ T cell responses induced by an adenovirus-vectored malaria vaccine in non-human primatesVaccine platforms combining circumsporozoite protein and potent immune modulators, rEA or EAT-2, paradoxically result in opposing immune responsesAdenovirus-5-vectored P. falciparum vaccine expressing CSP and AMA1. Part B: safety, immunogenicity and protective efficacy of the CSP componentFusion of antigen to a dendritic cell targeting chemokine combined with adjuvant yields a malaria DNA vaccine with enhanced protective capabilitiesA New Method to Determine Antigen-Specific CD8+ T Cell Activity in Vivo by Hydrodynamic Injection.Recombinant Sindbis viruses expressing a cytotoxic T-lymphocyte epitope of a malaria parasite or of influenza virus elicit protection against the corresponding pathogen in mice.New gorilla adenovirus vaccine vectors induce potent immune responses and protection in a mouse malaria model.Viable adenovirus vaccine prototypes: high-level production of a papillomavirus capsid antigen from the major late transcriptional unit.Complete, long-lasting protection against malaria of mice primed and boosted with two distinct viral vectors expressing the same plasmodial antigenInfectivity of Plasmodium berghei sporozoites delivered by intravenous inoculation versus mosquito bite: implications for sporozoite vaccine trialsImmune responses against a single CD8+-T-cell epitope induced by virus vector vaccination can successfully control Trypanosoma cruzi infectionShort-term antigen presentation and single clonal burst limit the magnitude of the CD8(+) T cell responses to malaria liver stages.Replacing adenoviral vector HVR1 with a malaria B cell epitope improves immunogenicity and circumvents preexisting immunity to adenovirus in mice.Construction and immunogenicity of recombinant adenovirus vaccines expressing the HMW1, HMW2, or Hia adhesion protein of nontypeable Haemophilus influenzaeModification of Ad5 hexon hypervariable regions circumvents pre-existing Ad5 neutralizing antibodies and induces protective immune responsesA full-length Plasmodium falciparum recombinant circumsporozoite protein expressed by Pseudomonas fluorescens platform as a malaria vaccine candidate.Pathogen-induced proapoptotic phenotype and high CD95 (Fas) expression accompany a suboptimal CD8+ T-cell response: reversal by adenoviral vaccine.The Th1 immune response to Plasmodium falciparum circumsporozoite protein is boosted by adenovirus vectors 35 and 26 with a homologous insert.Immunogenicity and protection of a recombinant human adenovirus serotype 35-based malaria vaccine against Plasmodium yoelii in mice.Novel, chimpanzee serotype 68-based adenoviral vaccine carrier for induction of antibodies to a transgene product.Adenovirus particles that display the Plasmodium falciparum circumsporozoite protein NANP repeat induce sporozoite-neutralizing antibodies in miceA sufficient role of MHC class I molecules on hepatocytes in anti-plasmodial activity of CD8 (+) T cells in vivo.Long-term humoral and cellular immune responses elicited by a heterologous Plasmodium vivax apical membrane antigen 1 protein prime/adenovirus boost immunization protocol.Combining liver- and blood-stage malaria viral-vectored vaccines: investigating mechanisms of CD8+ T cell interference.Natural killer T cell ligand alpha-galactosylceramide enhances protective immunity induced by malaria vaccines.Dendritic cells genetically modified with an adenovirus vector encoding the cDNA for a model antigen induce protective and therapeutic antitumor immunity.Single-dose protection against Plasmodium berghei by a simian adenovirus vector using a human cytomegalovirus promoter containing intron AIdentification of non-CSP antigens bearing CD8 epitopes in mice immunized with irradiated sporozoites.Viral vector vaccines make memory T cells against malaria.Protective CD8 T cells against Plasmodium liver stages: immunobiology of an 'unnatural' immune response.Co-administration of α-GalCer analog and TLR4 agonist induces robust CD8(+) T-cell responses to PyCS protein and WT-1 antigen and activates memory-like effector NKT cellsIdentification of a suppressor mutation that improves the yields of hexon-modified adenovirus vectors.Recombinant viral vaccines expressing merozoite surface protein-1 induce antibody- and T cell-mediated multistage protection against malariaPreventing spontaneous genetic rearrangements in the transgene cassettes of adenovirus vectorsPhase I trial of recombinant adenovirus gene transfer in lung cancer. Longitudinal study of the immune responses to transgene and viral productsA retrospective evaluation of the role of T cells in the development of malaria vaccine.CD8 T-cell-mediated protection against liver-stage malaria: lessons from a mouse model.Human CD8+ T cells mediate protective immunity induced by a human malaria vaccine in human immune system mice.Dendritic cells can initiate protective immune responses against malaria.
P2860
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P2860
Single immunizing dose of recombinant adenovirus efficiently induces CD8+ T cell-mediated protective immunity against malaria.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年学术文章
@wuu
1997年学术文章
@zh
1997年学术文章
@zh-cn
1997年学术文章
@zh-hans
1997年学术文章
@zh-my
1997年学术文章
@zh-sg
1997年學術文章
@yue
1997年學術文章
@zh-hant
name
Single immunizing dose of reco ...... tive immunity against malaria.
@en
Single immunizing dose of reco ...... tive immunity against malaria.
@nl
type
label
Single immunizing dose of reco ...... tive immunity against malaria.
@en
Single immunizing dose of reco ...... tive immunity against malaria.
@nl
prefLabel
Single immunizing dose of reco ...... tive immunity against malaria.
@en
Single immunizing dose of reco ...... tive immunity against malaria.
@nl
P2093
P921
P1476
Single immunizing dose of reco ...... tive immunity against malaria.
@en
P2093
D Eichinger
E G Rodrigues
J M Wilson
P304
P407
P577
1997-02-01T00:00:00Z