c-CBL is not required for leukemia induction by Bcr-Abl in mice.

c-CBL is not required for leukemia induction by Bcr-Abl in mice.

Item
http://www.wikidata.org/entity/Q44679401
A BCR-ABL mutant lacking direct binding sites for the GRB2, CBL and CRKL adapter proteins fails to induce leukemia in miceAs4S4 targets RING-type E3 ligase c-CBL to induce degradation of BCR-ABL in chronic myelogenous leukemia.SHP-2 phosphatase is required for hematopoietic cell transformation by Bcr-Abl.FoxO tumor suppressors and BCR-ABL-induced leukemia: a matter of evasion of apoptosis.SOCS2 is dispensable for BCR/ABL1-induced chronic myeloid leukemia-like disease and for normal hematopoietic stem cell function.Inverse regulation of bridging integrator 1 and BCR-ABL1 in chronic myeloid leukemia.CBL-B is required for leukemogenesis mediated by BCR-ABL through negative regulation of bone marrow homing.Crk-associated substrate lymphocyte type regulates myeloid cell motility and suppresses the progression of leukemia induced by p210Bcr/Abl.
P2860

c-CBL is not required for leukemia induction by Bcr-Abl in mice.

Item
http://www.wikidata.org/entity/Q44679401
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh
2003年學術文章
@zh-hant
name
c-CBL is not required for leukemia induction by Bcr-Abl in mice.
@en
c-CBL is not required for leukemia induction by Bcr-Abl in mice.
@nl
type
label
c-CBL is not required for leukemia induction by Bcr-Abl in mice.
@en
c-CBL is not required for leukemia induction by Bcr-Abl in mice.
@nl
prefLabel
c-CBL is not required for leukemia induction by Bcr-Abl in mice.
@en
c-CBL is not required for leukemia induction by Bcr-Abl in mice.
@nl
P1433
P1476
P2093
P2860
P2888
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698
P921
P356
P1433
P1476
c-CBL is not required for leukemia induction by Bcr-Abl in mice.
@en
P2093
P2860
P2888
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698
P921