Functional role of the lock and key motif at the subunit interface of glutathione transferase p1-1.

Functional role of the lock and key motif at the subunit interface of glutathione transferase p1-1.

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http://www.wikidata.org/entity/Q44693903
Site-directed mutagenesis of mouse glutathione transferase P1-1 unlocks masked cooperativity, introduces a novel mechanism for 'ping pong' kinetic behaviour, and provides further structural evidence for participation of a water molecule in proton abHeterodimers of wild-type and subunit interface mutant enzymes of glutathione S-transferase A1-1: interactive or independent active sites?Phosphorylation of Glutathione S-Transferase P1 (GSTP1) by Epidermal Growth Factor Receptor (EGFR) Promotes Formation of the GSTP1-c-Jun N-terminal kinase (JNK) Complex and Suppresses JNK Downstream Signaling and Apoptosis in Brain Tumor Cells.A new nitrobenzoxadiazole-based GSTP1-1 inhibitor with a previously unheard of mechanism of action and high stability.Human cytosolic glutathione-S-transferases: quantitative analysis of expression, comparative analysis of structures and inhibition strategies of isozymes involved in drug resistance.Biochemical Characterization of the Detoxifying Enzyme Glutathione Transferase P1-1 from the Camel Camelus Dromedarius.A clickable glutathione approach for identification of protein glutathionylation in response to glucose metabolismThe intersubunit lock-and-key motif in human glutathione transferase A1-1: role of the key residues Met51 and Phe52 in function and dimer stabilityCatalytically active monomer of glutathione S-transferase pi and key residues involved in the electrostatic interaction between subunits.Overlapping protective roles for glutathione transferase gene family members in chemical and oxidative stress response in Agrobacterium tumefaciens.Evolution of Negative Cooperativity in Glutathione Transferase Enabled Preservation of Enzyme Function.Glutathione transferase P1-1 as an arsenic drug-sequestering enzyme.Insights into ligand binding to a glutathione S-transferase from mango: Structure, thermodynamics and kinetics.
P2860

Functional role of the lock and key motif at the subunit interface of glutathione transferase p1-1.

Item
http://www.wikidata.org/entity/Q44693903
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2003 nî lūn-bûn
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2003年の論文
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2003年学术文章
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name
Functional role of the lock an ...... glutathione transferase p1-1.
@en
Functional role of the lock an ...... glutathione transferase p1-1.
@nl
type
label
Functional role of the lock an ...... glutathione transferase p1-1.
@en
Functional role of the lock an ...... glutathione transferase p1-1.
@nl
prefLabel
Functional role of the lock an ...... glutathione transferase p1-1.
@en
Functional role of the lock an ...... glutathione transferase p1-1.
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P1433
P1476
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Functional role of the lock an ...... f glutathione transferase p1-1
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P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698