Assessment of a prepulse inhibition deficit in a mutant mouse lacking mGlu5 receptors.
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Norbin is an endogenous regulator of metabotropic glutamate receptor 5 signalingEmerging approaches for treatment of schizophrenia: modulation of glutamatergic signalingEnvironmental Enrichment Ameliorates Behavioral Impairments Modeling Schizophrenia in Mice Lacking Metabotropic Glutamate Receptor 5Disruption of mGluR5 in parvalbumin-positive interneurons induces core features of neurodevelopmental disorders.Anhedonia, avolition, and anticipatory deficits: assessments in animals with relevance to the negative symptoms of schizophreniaIron deficiency with or without anemia impairs prepulse inhibition of the startle reflex.Allosteric modulation of metabotropic glutamate receptors.Metabotropic glutamate receptors: from the workbench to the bedside.mGluR5 ablation in cortical glutamatergic neurons increases novelty-induced locomotionEvidence of missense mutations on the neuregulin 1 gene affecting function of prepulse inhibitionGenetic models of sensorimotor gating: relevance to neuropsychiatric disorders.Targeting glutamate synapses in schizophreniaPallidal hyperdopaminergic innervation underlying D2 receptor-dependent behavioral deficits in the schizophrenia animal model established by EGFRemoval of GABA(A) receptor γ2 subunits from parvalbumin neurons causes wide-ranging behavioral alterations.Age-associated improvements in cross-modal prepulse inhibition in miceModeling the positive symptoms of schizophrenia in genetically modified mice: pharmacology and methodology aspectsPrepulse inhibition and genetic mouse models of schizophrenia.Prepulse inhibition in fragile X syndrome: feasibility, reliability, and implications for treatment.The glutamatergic compounds sarcosine and N-acetylcysteine ameliorate prepulse inhibition deficits in metabotropic glutamate 5 receptor knockout mice.Identification of Metabotropic Glutamate Receptor Subtype 5 Potentiators Using Virtual High-Throughput Screening.mGluR5 has a critical role in inhibitory learning.The evolution of drug development in schizophrenia: past issues and future opportunities.Targeting metabotropic glutamate receptors for novel treatments of schizophrenia.mGluR5 positive allosteric modulators facilitate both hippocampal LTP and LTD and enhance spatial learningDevelopment of allosteric modulators of GPCRs for treatment of CNS disordersGroup I and group II metabotropic glutamate receptor allosteric modulators as novel potential antipsychotics.Interactive effects of mGlu5 and 5-HT2A receptors on locomotor activity in miceThe effects of the mGluR5 antagonist MPEP and the mGluR2/3 antagonist LY341495 on rats' performance in the 5-choice serial reaction time task.Neurodevelopmental Expression Profile of Dimeric and Monomeric Group 1 mGluRs: Relevance to Schizophrenia Pathogenesis and Treatment.Activation of metabotropic glutamate receptors as a novel approach for the treatment of schizophrenia.Metabotropic glutamate receptors: physiology, pharmacology, and disease.Metabotropic glutamate receptor subtype 5: molecular pharmacology, allosteric modulation and stimulus biasGroup I Metabotropic Glutamate Receptor Interacting Proteins: Fine-Tuning Receptor Functions in Health and Disease.Allosteric Modulation of GPCRs: New Insights and Potential Utility for Treatment of Schizophrenia and Other CNS Disorders.Altered expression of schizophrenia-related genes in mice lacking mGlu5 receptors.Stimulation of group I mGlu receptors in the ventrotegmental area enhances extracellular dopamine in the rat medial prefrontal cortex.Protein kinase A directly phosphorylates metabotropic glutamate receptor 5 to modulate its function.Bursting of prefrontal cortex neurons in awake rats is regulated by metabotropic glutamate 5 (mGlu5) receptors: rate-dependent influence and interaction with NMDA receptors.Clozapine reverses schizophrenia-related behaviours in the metabotropic glutamate receptor 5 knockout mouse: association with N-methyl-D-aspartic acid receptor up-regulation.A postmortem analysis of NMDA ionotropic and group 1 metabotropic glutamate receptors in the nucleus accumbens in schizophrenia.
P2860
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P2860
Assessment of a prepulse inhibition deficit in a mutant mouse lacking mGlu5 receptors.
description
2004 nî lūn-bûn
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2004年の論文
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2004年学术文章
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2004年学术文章
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2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
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2004年學術文章
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2004年學術文章
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name
Assessment of a prepulse inhibition deficit in a mutant mouse lacking mGlu5 receptors.
@en
Assessment of a prepulse inhibition deficit in a mutant mouse lacking mGlu5 receptors.
@nl
type
label
Assessment of a prepulse inhibition deficit in a mutant mouse lacking mGlu5 receptors.
@en
Assessment of a prepulse inhibition deficit in a mutant mouse lacking mGlu5 receptors.
@nl
prefLabel
Assessment of a prepulse inhibition deficit in a mutant mouse lacking mGlu5 receptors.
@en
Assessment of a prepulse inhibition deficit in a mutant mouse lacking mGlu5 receptors.
@nl
P2093
P2860
P356
P1433
P1476
Assessment of a prepulse inhibition deficit in a mutant mouse lacking mGlu5 receptors.
@en
P2093
P2860
P2888
P356
10.1038/SJ.MP.4001404
P407
P577
2004-01-01T00:00:00Z