A DNA enzyme that mimics the first step of RNA splicing.
about
A deoxyribozyme that synthesizes 2',5'-branched RNA with any branch-site nucleotideStructure-function analysis of yeast RNA debranching enzyme (Dbr1), a manganese-dependent phosphodiesterase.Crystal structure of a DNA catalystPursuing DNA catalysts for protein modificationFunctional nucleic acid sensorsPractical and general synthesis of 5'-adenylated RNA (5'-AppRNA).Zn2+-dependent deoxyribozymes that form natural and unnatural RNA linkages.Efficient RNA 5'-adenylation by T4 DNA ligase to facilitate practical applications.DNA-catalyzed serine side chain reactivity and selectivity.DNA-catalyzed lysine side chain modificationUse of deoxyribozymes in RNA research.A general two-step strategy to synthesize lariat RNAsImproved deoxyribozymes for synthesis of covalently branched DNA and RNA.Efficient one-step synthesis of biologically related lariat RNAs by a deoxyribozymeDNA-catalyzed reactivity of a phosphoramidate functional group and formation of an unusual pyrophosphoramidate linkage.DNA as a versatile chemical component for catalysis, encoding, and stereocontrolCharacterization of Z-DNA as a nucleosome-boundary element in yeast Saccharomyces cerevisiae.In vitro selection of a 5'-purine ribonucleotide transferase ribozyme.Adenosine is inherently favored as the branch-site RNA nucleotide in a structural context that resembles natural RNA splicing.Convergent and general one-step DNA-catalyzed synthesis of multiply branched DNA.Deoxyribozymes: selection design and serendipity in the development of DNA catalysts.Controlling the direction of site-selectivity and regioselectivity in RNA ligation by Zn2+-dependent deoxyribozymes that use 2',3'-cyclic phosphate RNA substrates.Generation and selection of ribozyme variants with potential application in protein engineering and synthetic biology.Mg2+-dependent conformational changes and product release during DNA-catalyzed RNA ligation monitored by Bimane fluorescence.DNA Catalysis: The Chemical Repertoire of DNAzymes.Biochemical and Biophysical Understanding of Metal Ion Selectivity of DNAzymes.Functional Hallmarks of a Catalytic DNA that Makes Lariat RNA.Nucleic acids: function and potential for abiogenesis.Crystal structure of an RNA-cleaving DNAzyme.Probing the effect of minor groove interactions on the catalytic efficiency of DNAzymes 8-17 and 10-23.Combinatorial mutation interference analysis reveals functional nucleotides required for DNA catalysis.
P2860
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P2860
A DNA enzyme that mimics the first step of RNA splicing.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
@zh-hant
name
A DNA enzyme that mimics the first step of RNA splicing.
@en
A DNA enzyme that mimics the first step of RNA splicing.
@nl
type
label
A DNA enzyme that mimics the first step of RNA splicing.
@en
A DNA enzyme that mimics the first step of RNA splicing.
@nl
prefLabel
A DNA enzyme that mimics the first step of RNA splicing.
@en
A DNA enzyme that mimics the first step of RNA splicing.
@nl
P2860
P356
P1476
A DNA enzyme that mimics the first step of RNA splicing.
@en
P2093
Rebecca L Coppins
Scott K Silverman
P2860
P2888
P304
P356
10.1038/NSMB727
P577
2004-02-01T00:00:00Z
P5875
P6179
1014975104